Research published in Blood concluded that a compound found in fish oil kills cancer causing stem cells in the spleen and bone marrow of mice by activating a gene-p53-in leukemia stem cells that program the cell’s own death. “p53 is a tumor suppressor gene that regulates the responses to DNA damage and maintains genomic stability” according to the researcher. Killing the stem cells is important because they can divide and and produce more cancer cells.
The compound from fish oil that seems to target leukemia stem cells is delta-12-protagiandin J3, or D12-PGJ3. It killed the stem cells of chronic myelogenous leukemia (CML) in mice.
Current treatment for leukemia is unable to kill the leukemia stem cells and the patient must continue to take medications or the disease will relapse because stem cells are resistant to the drugs. Thus, this is an important discovery.
During the study, researchers injected each mouse with about 600 nanograms of D12-PGJ3 daily for a week. Results showed that the mice were completely cured, the blood count was normal, and the spleen returned to a normal size. There was no relapse of the disease.
The researchers are currently studying whether or not the compound can be used to treat terminal stages of CML because currently there are no drugs available that can treat this stage of the disease.

A new study reported in Cancer Prevention Research concluded that men who ate a low-fat diet with fish oil supplements from 4 to 6 weeks before having their prostate removed had slower cancer-cell growth in their prostate tissue than men who ate the typical high-fat Western diet. The cell membrane of both healthy and cancer cells in men on the low-fat diet with fish oil supplements also showed changes in that there were higher levels of omega-3-fatty acids from fish oil and lower levels omega-6-fatty acids from corn oil. Researchers also found that blood from patients using the low-fat supplemented by fish oil diet slowed the growth of prostate cancer cells in a test tube whereas blood from those on the typical diet did not. The researcher said “The findings that the low-fat, fish oil diet reduced the number of rapidly growing cells in the prostate cancer tissue is important because the rate at which the cells are dividing can be predictive of future cancer progression. The lower the rate of proliferation, the lesser the chances that the cancer will spread outside the prostate, where it is much harder to treat.”

The study included 48 men followed over 6 weeks. Men in the low-fat fish oil supplemented diet group were provided food to assure that they followed a low-fat diet supplemented with fish oil The diet provided 15 percent of the calories from fat and was supplemented with 5 grams of fish oil daily. The typical diet provides 40 percent of the calories from fat and usually has high levels of omega-6 fatty acids from corn oil and low levels of fish oil that provides omega-3 fatty acids and that have been found to reduce the incidence of heart disease and to fight inflammation that has been associated with certain types of cancer.

The researchers warn against generalizing from this study because of the small numbers and short period of study. Another study in planned that will include 100 men with prostate cancer who have elected to wait and see without any treatment but will receive biopsies and check-ups. The study will randomly divide men into two groups-the low fat fish oil supplemental diet and the typical western diet and follow them for 1 year to evaluate the effect of diet on prostate cancer cell proliferation.

Yesterday on the Holistic Health Show Dr Carl O Helvie, Host, Holistic Health Show interviewed Dr Michael T Smith (above left) and Ron Brown.

Dr Smith is a naturopathic physician who specializes in homeopathy and nutrition for conditions including diabetes. He practices at the Carolinas Natural Health Center in Matthews, North Carolina. More information was presented earlier on this site or can be found at: www.CarolinasNaturalHealth.Com

Ron Brown is a retired hotel night auditor who cared for his wife when she was diagnosed with diabetes. More information was presented earlier on this site and can be found at: www.webeardiabetes.com

Enjoy the interview below:

Yesterday, Dr Carl O Helvie, Host, Holistic Health Show interviewed Dr Michael Murray and Dr Michael T. Smith for the opening of the Series on Diabetes.

Dr Michael Murray is author of over 30 books including How to Prevent and Treat Diabetes with Natural Medicine. and has appeared on hundreds of radio and T.V., shows. He is chairman of Dr Murray Natural living and is one of the world’s leading authorities on natural medicine. more information was presented earlier on this site or can be found at: http://www.doctormurray.com

Dr Michael T. Smith is a naturopathic physician who specializes in classical homeopathy and nutrition and is part of the North Carolina Association of Naturopathic Physicians. He practices at the Carolina’s Natural Health Center in Matthews, North Carolina. More information was presented earlier on this site or can be found at: http://www.carolinasnaturalhealth.com

Enjoy the Interviews Below:

Dr Carl O Helvie, host, interviewed Dr Dobri Kiprov and Dr Ann Lovick on the Holistic Health Show yesterday. Both talked about natural solutions for seasonal allergies.

Dr Kiprov a physician and pioneer in the field of immunology is chief of immunology at California Pacific Medical Center in San Francisco. He is world renown for his work. More information is available on an earlier blog and at: www.lifestyleinmotion.com and www.dobrikiprov.com

Dr Lovick is a naturopathic physician who is on the staff of Integrative Health Care in Scottsdale, Arizona and has been a lifelong sufferer of allergies. More information is available on an earlier blog and also at: Http://integrativehealthcare.com/drlovick.htm

The interview follows:

Research published in Cancer Epidemiology, Biomarkers & Prevention concluded that regular use of fish oil may reduce the risk of breast cancer. Researchers asked over 35,000 post-menopausal women who did not have breast cancer to complete a questionaire about their use of non-vitamin. non-mineral “specialty” supplements in the Vitamins and Lifestyle cohort study. Following 6 years there were 880 cases of breast cancer. Those who regularly used fish oil supplements with high levels of omega-3 fatty acids, EPA and DHA had a 32% reduced risk of developing breast cancer. Other supplements commonly taken by post menopausal women did not show an association with breast cancer risk. The researchers cautioned that these findings should not be considered final without replicated studies. Further studies are planned by the researcher.

Dr Jacob Teitelbaum (left) and Dr David Russell were interviewed by Dr Carl O. Helvie on the Holistic Health Show last night. Dr Teitelbaum, a Board Certified Internist and Medical Director of a National Chain of Fibromyalgia and Fatigue Centers (www.fibroandfatigue.com)suffered from and overcome these diseases. He is senior author of landmark studies in these areas and author of the best seller From Fatigue to Fantasy and also author of additional books mentioned earlier on this website. More information is available on www.Vitality101.com

My second guest, Dr Davids Russell, holds a doctorate in Naturopathic Medicine and is competing another Doctorate of Divinity and is the Founder and Director of the non-profit organization Caritas Traditionalis whose goal is to create a self-sustainable medical presence in economically depressed communities. He has studied classical medicine around the world including Europe, Nepal and the Middle East. More information can be found on an earlier blog here.

Their interviews follow. I hope they are informative for you.