Posts Tagged ‘non-toxic’

Is High Dose Vitamin C safe?

Wednesday, April 5th, 2017

 

Holistic-Health-Show-with-Dr-Carl-O-HelvieA new study published in Cancer Cell researchers found in clinical studies that it was safe to regularly infuse brain and lung cancer patients with 800 to 1,000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments. In addition, they showed pathways by which altered iron metabolism in cancer cells, and not normal cells, lead to increased sensitivity to cancer cell death caused by high dose vitamin C.

In the study 11 patients enrolled in the brain cancer safety trial and received three infusions of vitamin C a week for 2 months followed by two infusions per week for 7 months while receiving standard care of radiation and chemotherapy. The goal of each infusion was to raise the concentration of vitamin C in a patients blood to 20,000 uM, as compared to a blood level of          70 uM found in most adults. A high dose is necessary because vitamin C has a half life of around two hours in circulating human blood. The treatment was generally well tolerated except for frequent trips to the bathroom and dry mouth. (as an aside, dry mouth was the one symptom mentioned by Dr Francisco Contreras at the Oasis of Hope where they have used high dose vitamin C with cancer patients). Researchers found that occasionally patients had elevated blood pressure that subsided quickly following infusion.

The safety of the high dose vitamin C is due to the fact that it is not toxic to normal cells but when interacting with cancer cells the high levels of redox active iron molecules in the cancer cells reacts with the vitamin C to form hydrogen peroxide and free radicals formed from hydrogen peroxide. The free radicals are believed to cause DNA damage selectively in the cancer cells that lead to cancer cell death and sensitivity to radiation and chemotherapy in cancer cells. (This has been long known by alternative doctors who use the high dose vitamin C without the chemo and radiation).  Researchers said “This is a significant example of how knowing details of potential mechanisms and the basic science of redox active compounds in cancer versus normal cells can be leveraged clinically in cancer therapy.” …Here , we verified convincingly, that increased redox active metal ions in cancer cells were responsible for the differential sensitivity of cancer versus normal cells to very high doses of vitamin C.” Further studies on safety and vitam C are planned.

Is Excessive Vitamin E Intake a Health Concern?

Wednesday, April 24th, 2013

logo1267406_mdA new study published in the Journal of Lipid Research concluded that biological mechanisms exist to routinely eliminate excessive levels of vitamin E in the body that make it almost impossible to take a harmful amount.  An expert from the linus Pauling Institute at Oregon State University says no level of vitamin E in the diet of from any normal us of supplementation should be a concern and another international expert said ” I believe that past studies which have alleged adverse consequences from vitamin E have misinterpreted the data.” Taking too much vitamin  E is not the real concern.” “A much more important issue is that more than 90% or people in the united /States have inadequate levels of vitamin E in their diets.”

In their review of how vitamin E is metabolized the researchers found that two major systems in the liver work to control the level of vitamin E in the body and routinely excrete excessive amounts. Very high levels of vitamin E supplements will double the tissue levels which are not harmful according to the article. The researcher said “Toxic levels of vitamin E in the body simply do not occur. Unlike some other fat soluble vitamins such as Vitamin A and D, it’s not possible for toxic levels of vitamin E to accumulate in the liver and other tissues.”

Vitamin E found in oils, meat and some other fo0ds  is often consumed in inadequate dietary levels and is an antioxidant needed for proper functioning of many organs, nerves, and muscles. and can reduce blood clotting.  Other roles include protecting polyunsaturated fatty acids from oxidizing,  may help protect other essential lipids, and may have value in many degenerative diseases.

(It is of interest that I used high doses of vitamin E as part of my treatment regime for lung cancer 38 years ago to help reduce the toxic effects of therapeutic does of vitamin A and was a concern to me at the time because both were fat soluble vitamins.)

 

Could a Cup of Herbal Tea Help Fight Breast Cancer?

Friday, August 31st, 2012

A news release from Aston University on August 24 concluded that a cup of herbal tea might fight breast cancer. The plant, Fagonia cretica, known as Virgon’s Mantlem, is commonly used as an herbal tea in Pakistan and has traditionally been used by rural women with breast cancer.  Although in the past it has been regarded as folklore, women reported that it had none of the serious common side effects associated with other cancer treatment such as loss of hair, a drop in blood count, or diarrhea.

Now researchers at Aston University and Russell Hall Hospital have started testing the plant extract and find it is responsible for killing cancer cells without damaging normal breast cells in laboratory conditions. Next, the researchers plan to determine the element or elements in the extract that kill the cells and then follow up with human cancer patients. The researchers say “More research is needed to establish the role of the extract in cancer management and it now needs to be demonstrated that the extract is effective in killing cancer cells inside the body as it is within laboratory.”  “Some of the most important cancer-fighting drugs are originally derived from plants. As this research is in the very earliest stage we wont know for quite some time whether drugs derived from this plant will be effective in treating breast cancer but will look forward to seeing any progress.”