Can Vegetables Effective Treat Breast Cancer?

A new study published online in Hormones and Cancer concluded that apigenin, extracted from celery, parsley and many other natural sources, is effective against human breast cancer cells that had been influenced by a certain chemical, progestin, used in hormone replacement therapy.

In the study, researchers implanted cells of a deadly, fast growing human breast cancer, known as BT-474, into a  specialized breed of mouse. Some of the mice were treated with medroxyprogesterone acetate (MPA), a type of progestin, often given to post-menopausal women. A second group, the controls, did not receive the MPA.  Later one group of the MPA treated mice were treated with apigenin and another was not. Cancerous tumors grew rapidly in mice not receiving apigenin. However, in the group receiving apigenin, cancer cell growth dropped to the level of the control group and their tumors shrank. It was determined that apigenin slowed the progression of breast cancer cells in three ways: 1)Inducing cell death; 2) Inhibiting cell proliferation; and 3) Reducing the expression  of a gene associated with cancer growth. Researchers said “Apigenin has shown no toxic side-effects even at high doses.”  More research is planned.

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