New Less-Invasive Method for Detecting and Monitoring Prostate Cancer

A recent study published in the online Journal of Urology concluded that contrast-enhanced ultrasound was better at detecting high grade prostate cancer than conventional methods making it more appropriate for screening and monitoring with less biopsies. The randomized, double bind study used microbubbles to measure changes in blood flow and found almost three times as many higher grade cancers using half as many needle biopsies compared to systemic biopsy methods. The lead researcher said “Today, a physician may sample 12 to 18 tissue cores from the prostate in order to help diagnose a patient.  But with contrast-enhanced, that number drops to six or even less.”  “So it’s less invasive, and a more effective tool.”

In the clinical trial of 311 men, 118 had positive prostate cancer biopsies revealing that targeted biopsies using contrast-enhanced ultrasound witrh microbubbles detected significantly more  higher voolume/grade prostate cancers (clinically significant) in men (55 percent) compared toi a conventiuonal prostate buiopsy technique (17 percent). All subjects received targeted biopsies using contrast-enhanced ultrasound with flash replenishment maximum intensity projection MicroFlow Imaging and a systemic 12-core biopsy protocol for comparison. The mean age of suvjects was 62 years and a PSA of 6.5ng/ml.

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