Will Increasing Flavonoid Intake Reduce the Risk for Agressive Prostate Cancer?

A new study presented at the 11th annual AACR International Conference on Frontiers in Cancer Prevention Research concluded that a high intake of flavonoids, a group of compounds found in plants, are inversely associated with the risk for highly aggressive prostate cancer. The researcher said “Incorporating more plant-based foods and beverages, such as vegetables, herbs, and tea, into the diet may offer some protection against aggressive prostate cancer.”

Using data from 920 African-American men and 977 European American men newly diagnosed with prostate cancer, subjects were asked to complete a self-reported dietary history questionaire that assessed flavonoid intake measured against the U.S. Department of Agriculture 2011 Database for Flavonoid Content of Selected Foods. Men with the highest total intake of flavonoids had a 25% lower risk of aggressive prostate cancer compared to those men with the lowest favonoid intake. The researcher said “We found that higher total flavonoid intake was associated with reduced odds for aggressive prostate cancer in both Africa-American and European-American men, but no individual subclass of flavonoids appeared to be protective independently, suggesting that it is important to consume a variety of plant-based rather than focus on one specific type of flavonoid or flavonoid-rich food.”  They also found the risk lower in men under age 65 and in current smokers with high levels of flavonoids intake. The top category of flavonoid intake among the subjects were citrus fruit and juices, such as oranges and grapefruits, tea, grapes, strawberries, onions, and cooked greens.

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