Is BPA Linked to Breast Cancer Tumor Growth?

logo1267406_mdA new study published online in the Journal of Steroid Biochemistry and Molecular Biology concluded that their research results could not say that bisphenol-A (BPA) causes breast cancer but it could contribute to its growth because it disrupts the genes that defend against that growth., BPA is a synthetic compound that has been widely used in plastics, such as food storage containers, the lining of canned food containers, and until recently baby bottles.

Researchers found that when breast cancer and mammary gland cells were exposed to BPA in lab tests, the BPA worked together with naturally present molecules such as estrogen to create abnormal amounts of HOTAIR expression. HOTAIR is a part of long, non-coding RNA,that does not produce a protein on its own but, when it is being expressed or functioning, it can suppress genes that would normally slow tumor growth or cause cancer cells to die and has been linked to breast tumors, and others. Researchers said “We weresuprised to find that BPA not only increased HOTAIR in tumor cells but also in normal breast tissue.”

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