Archive for the ‘brain cancer’ Category

Glioblastoma Research Shows Tumor Cell Death in Cell and Animal Studies Using Antihistamines.

Wednesday, July 17th, 2019

A new study published in EMBO Molecular Medicine Journal concluded that “antihistamines and other drugs that increase the permeability of the lysomal membrane can be considered as an enhancing therapy for patiets with glioblastoma alongside established treatments.” In the research they found that “glioblastoma cells depend upon the expression of a gene which produces the MDGI protein (small fatty acid binding protein). Inhibiting of this gene results in the death of the tumor cells.” The absence of MDGI causes instability in the membranes of lysosomes, cleaning organelles found inside tumor cells, and in turn, resulting in the leakage of acidic and proteolytic enzymes contained in the lysosomes into the cytoplasm, initiating cell death. Reasearchers said their research “demonstrates that MDGI  is a key factor regulating and maintaining the structure of the lysosomal membrane. This is the first gene found to regulate the stability of the membrane.”  Their results are especially interesting because they found that cell death caused by leakage in the lysosomes of glioblastoma can be activated by using drugs that cross the blood-brain barrier” and in this study they used the antihistamine clemastine.

In cell cultures the antihistamine in lysosome-initiated cell death in glioblastoma cells were at concentrations that has no significant effect on healthy cells of different types.  In mouse models it was effective in reducing the spread of brain tumors and improving the survival rates of the animals. In the most invasive brain tumor model, the antihistamine resulted in the disappearance of the entire tumor.




Cherie Colborn /Cheryl Broyles Interviews.

Sunday, February 26th, 2017

 Cherie Colborn (Juice Lady) and Cheryl Boyles (Cancer Survivor used Cannabis) next guests. NOTE THE OFFER FOR A SCHOLARSHIP TO THE FREE WEEK LONG RETREAT BELOW.


Cherie Calbom MSN holds a Master of Science degree in whole foods nutrition from Bastyr University. Known as “The Juice Lady” for her work with juicing and health, she is the author of 32 books including her latest The Juice Lady’s Guide to Fasting and Sugar Knockout. She and her husband offer juice cleanse retreats throughout the year, 30-Day Detox online and Garden’s Best Juice Powder. She received a grant to study “Nutrition: The Missing Piece of the Cancer Treatment Puzzle.” She has lectured worldwide on juicing, detoxing and fasting including consulting for the Royal Family of the UAE. She appears in the 9-Episode DVD series The Truth About Cancer. Winner of the TTAC Lifetime Achievement Award for her work with juicing and detoxification, her blogs and books on juicing, cleansing and health have helped thousands of people live healthier lives. You can connect with her on Facebook and Twitter and sign up for her free newsletter at
N.B.  FREE OFFER  FOR CANCER AND/OR RADIO LISTENER: Cherie offered the following scholarship and a partial scholarship for another listener for her next retreat. She said:

I’m so very impressed with your story. I applaud you and your life of service.
What I can do for your followers is to offer a scholarship to someone who really needs to cleanse their body at our juice & raw foods retreat. Many people have been healed when they have attended. We’ve had some people with cancer who have gone home with tumors that had shrunk in the week with us. I also have a  partial scholarship as well where they pay just $600. This will be my gift to your followers. To apply, they simply send me an email letter as to why they want to attend. They also must send their latest tax return as proof of financial need. Send these to:  Cherie Calbom <> The deadline is March 15, 2017.
Details about the retreat can be found at:   You will note it is from April 30 to May 5 in Spokane, Washington. You will be responsible for transportation to and from the retreat and will have meals and room while there. There is one free scholarship and one half price scholarship for $600.00.  We will announce the winners after selection. Good luck.
Further information at:
2009 stitches
Cheryl showing her sutures from 2009 operation.

Cheryl Boyles  tells us her story below. In June 2000 I was 33 years old, working as a wildlife biologist in Oregon, married to a wonderful husband for 10 years, and the mother of two amazing sons that were 1 and 3 years old.  I was loving life; then overnight my life changed.  I began having headaches that felt like my skull was going to explode.  An MRI showed my brain was hemorrhaging.  I went into surgery and an acorn sized grade 4 Glioblastoma Multiforme (GBM) brain tumor was removed.  I was told I had less than a year to live.I quit my job, and focused on being a mother and fighting brain cancer.  I went through radiation, but chose not to take chemotherapy.  The chemo would only add 3 months to my life, but quality of life would be miserable.

I decided to take more of a natural “alternative” approach, trying to boost my own immune system.  My good cells outnumbered my bad cancer cells! I started eating organic, following a low carbohydrate diet, exercising, simplifying life and nursing a positive attitude, taking acupuncture, many supplements, cannabis, some “off label” prescriptions (like Metformin), and most of all leaning on God for strength which feeds me with hope.

Over the 16 years fighting the terminal brain cancer, I’ve unfortunately was hit with six recurrences. The fact that I have survived is unbelievable.  My doctors even say so.  Most people with the GBM die with their first recurrence, which usually happens within the first few years.  To fight my recurrences, I mostly focused on my alternative actions, but also continued with some of the standard treatments.  I’ve been through six brain craniotomies, 6 week of conformation radiation, over 3 ½ years on the milder chemo called Temodar, and also what is called Gamma Knife radiation.

Taking this approach of combining many alternative and standard treatments, trying to hit the cancer from many angels, has become known at a “cocktail” approach.  It seems to be working for me, not that I’m cured, but I’m still alive and loving life.  Over the sixteen years I’ve had over 100 MRIs, and it’s great to say that my last MRI was clear, no seen GBM.I have become known in the “brain tumor world” as a long term survivor.  Patients and caregivers from around the USA and around the world contact me wanting to know “How do you do it?”  So I’ve put together a web page, wrote a book called Life’s Mountains, and made some videos hoping to reach out and encourage others.

Now my husband and I have been married 26 years, growing stronger together.  My two boys are now 17 and 20 years old, both wanting to become wildlife biologists like mom and dad.   And over the years I’ve been blessed with many things.  Seeing life anew, learning to be content regardless of circumstances, enduring through the challenges, and living life in the moment.

Enjoy the Interview Below:







Is Non-Surgical Diagnosis of Brain Tumors Possible?

Friday, April 27th, 2012

The results of a pilot study published in the online edition of Neuro-Oncology demonstrated that brain tumors can be reliably diagnosed and monitored without surgery. Previously unavailable or unreliable the researchers said ” We are excited about the potential that this test has to ease the process of detecting and monitoring brain tumors.” “The test needs to be further developed before it is used in a clinical setting, but I expect it could be particularly valuable for patients who are not surgical candidates.”

In the pilot study of 118 patients with different types of brain tumors, the researchers showed that micro RNA profiling of cerebrospinal fluid can be used to determine the presence of glioblastoma, the most common and lethal form of brain cancer. The micro or tiny RNA molecules are excellent bio markers for various conditions and their levels can be accurately measured in body fluids so it is a simple and inexpensive procedure. This same process could be used to detect the presence of cancer that started in another body site and spread to the brain as well as monitoring the tumor during treatment.

Brain Tumor Spread May Be Blocked by a Chinese Herbal Componentt

Wednesday, July 20th, 2011


New research reported online in the journal Cancer Research concluded that an active ingredient, indirubin, found in a traditional Chinese herbal remedy known as Dang Gui Long Hui Wan may be useful in the treatment of brain tumors. The component blocks migration of glioblastoma cells to other areas of the brain and \also the migration of endothelial cells preventing the formation of new blood vessels needed by the tumor to grow.
Using multiple glioblastoma cell lines and two animal models three derivatives of indirubin were examined. Findings showed transplanting glioblastoma cells into one brain hemisphere of mice increased survival significantly longer than controls and showed no migration of tumor cells to the other hemisphere. In another study, the migration of tumor cells were reduced by 40% in treated mice verses controls.
Indirubins also reduced endothelial-cell migration by 52 to 41 percent compared to untreated controls and a lower density of blood vessels and new blood vessel growth was reduced up to three-fold in intracranial tumors, depending upon the tumor-cell line. Thus, the researchers concluded that “findings suggest that indirubins reduce tumor invasion and tumor vasculature because of their antimigratory effects on both tumors and endothelial cells.”

Exercise Increased Survival Time Following Brain Cancer Diagnosis

Friday, July 1st, 2011


Research published in the June 20 online issue of the Journal of Clinical Oncology concluded that brain cancer patients who exercise live significantly longer than sedentary patients. Two hundred forty three patients with advanced recurrent lethal brain malignancies at Duke were enrolled in the study. Those diagnoses with this type of cancer usually have a median life expectancy of less than 6 months. In the study those who reported regular brisk exercise defined as the equivalent of an energetic walk for thirty minutes five days a week lived a median 21.84 months compared to 13.03 months for those who were most sedentary.

Cell Phone Use and Brain Tumors

Friday, January 28th, 2011


There has long been a debate about the use of cell phones and the development of brain and other types of tumors and many studies in the past have concluded that there is an association. The most recent study was reported in the November/December issue of the Journal of Computer Assisted Tomography . In this report the researchers conducted an in-depth analysis of research on the risk of wireless phones (cell and home cordless Phones). A review of the past ten years or longer produced 11 published studies on long term use of cell phones and the risk of brain tumors. This review of studies produced conflicting results. One of the largest studies concluded that cell phone use did not increase the risk of brain tumors. Two flaws were identified in this study: it was largely funded by the wireless communications industry that may have caused a bias , and it was of a short duration.

A series of independent studies carried out by a cancer specialist in Sweden found different results. He found that the more hours of cellular phone use over a longer period of time (ten years or longer) the higher the risk of developing brain tumors. He also found the level of power from the wireless phone, the years since beginning use, the total exposure, and younger age all increased the risk of developing brain tumors.

Based upon an analysis of all studies the researchers concluded “long term cell phone usage can approximately double the risk of developing a glioma or acoustic neuroma in the more exposed brain hemisphere.” Although it is unclear how this exposure can increase the risk of brain cancer studies have shown that the cell signal is absorbed up to 2 inches in the adult skull. More research is needed to validate these findings.

Cancer Cell Growth May Be Slowed by Blocking Sugar Pathways

Wednesday, November 24th, 2010


Research from Johns Hopkins University published online in the November 15 issue of Cancer Research and as a news alert from Johns Hopkins (see link below) “concluded that researchers have identified a compound that might be used to starve cancer cells of their sugar-based building blocks.” Although not tested on humans or animals yet, the compound, a glutaminase inhibitor called BPTES, has been tested on lab cultured sugar-hungry brain cancer cells. In their research they used BPTES on cells engineered to have IDHI mutations that seem to convert cell building blocks to nutrients that feed cancer cells. Results show that cancer cells growth was reduced by 30%. Thus, it did not completely stop cancer cell growth. but slowed its progress. Further research is planned to refine BPTES and to try it with other types of cancer cells. Additional information is available at:

Treating Brain Cancer with Viruses

Friday, May 14th, 2010


Some parvoviruses have been shown to kill tumor cells without harming healthy tissue and have been tested previously in cancer therapy.

Using a particular parvovirus, the parvovirus H-1, researchers at the German Cancer Research Center studied with rats who received brain tumor cells by implantation. When the brain tumors reached a specific size the rodents were given parvoviruses either by direct injection into the tumor or into the blood stream. In rodents injected directly into the tumor the tumor shrank visibly after three days and disappeared in eight of the 12 rodents treated. They survived without any symptoms. The untreated rodent controls had severe disease symptoms within 3 weeks following the tumor implantation.
In the rodents who received injections into the blood stream six of nine rodents showed regression of the tumor and all treated rodents survived for one year with no signs of side effects.
There was no infection-related damage in the nervous tissue surrounding the tumor in the treated rodents and the virus did not spread to the whole organism. Parvovirus DNA was found in all organs after several days following transfer but that only lasted for a short time. Despite the viruses infecting healthy tissue they did not reproduce as they did in the tumor tissue where they reproduced and the viral protein production was detected. In rats that did not have tumors, the virus did not reproduce. The researchers concluded that the presence of cancer cells seem to be necessary for the parvovirus to reproduce. They believe these viruses are suitable for use in cancer treatment. More information is available at:
Helmholtz Association of German Research Centers (2010, May 5) Viruses effective against brain cancer in animals. Human trials set to start. ScienceDaily. Retrieved May 9, 2010., from releases/2010/05/100504095106.htm

Dr Carl O Helvie Interviews 5 Cancer Survivors

Sunday, July 19th, 2009


On Saturday, July 18, I interviewed 5 cancer survivors pictured from left to right–Aurea McGarry, Linda Wilson, Regina Leeds, Les Thiele, and Lori Kuban .

Aurea is a 9 year Non Hodskins Lymphoma survivor who won the Mrs. U.S. Beauty of Georgia Contest in 2003 and the title of Most Inspirational Contestant. She is the creator, producer and host of the television show Live Your Legacy with Aurea McGarry. Earlier she worked on the soap opera Edge of Night. She discusses her experiences with cancer in her book I Won’t Survive, I’ll Thrive. More information is available at:

Linda had a tumor of the kidney and used alternative interventions. She and her husband have owned a rare and used book business for 25 years. She has degrees in English Literature, and Respiratory Therapy, and a Masters in Theology. She is an ordained Episcopal Minister but currently works with the Catholic Apolistic Church. She writes when she has time and has a novel placed with an agent currently. She can be reached at:

Regina is a 7 year survivor of third stage uterine cancer who used traditional and alternative interventions. She is a professional organizer and authored six books including the New York Times best seller One Year to an Organized Life. More information is available at

Les is a 3 time ovarian cancer survivor who used complementary interventions. She talks with cancer patients several times a week and is in the process of putting up a web site. She can be reached at: (617) 834-1597.

Lori is a brain tumor survivor who used traditional and alternative interventions. She has a baccalaureate and masters degree and is a research librarian. She is also a cancer and health care advocate who speaks and provides workshops for cancer survivors and professionals including being a spokesperson for the American Cancer Society. She also gives radio and television interviews. More information is available at

The interviews for this show follow.

Cancer Survivors Interviewed by Dr Carl O Helvie on the Holistic Health Show

Wednesday, July 15th, 2009

Linda Wilson, Aurea McGarry and Lori Kuban will also be interviewed on the Holistic Health Show on Saturday.
Linda had a tumor of the kidney and used alternative interventions. She and her husband have owned a rare and used book business for 25 years. She has degrees in English Literature, Respiratory Therapy and a masters in Theology. She is an ordained Episcopal minister but currently works with the Catholic Apolistic church. She writes when she has time and currently has a novel placed with an agent. She can be reached at
Aurea is a 9 year non hodgkins lymphoma sur-THRIVER. She won the Mrs U.S. Beauty of Georgia Contest in 2003 and the title of Most Inspirational Contestant. She is the creator, producer, and host of the television show Live Your Legacy with Aurea McGarry. Earlier she worked on the soap opera The Edge of Night. She discusses her experience in her book I Won’t Survive, I’ll Thrive. More information is available at
My third guest, Lori, is a brain tumor survivor who used traditional and alternative interventions. Lori has baccalaureate and masters degrees and is a research librarian. She is a cancer and health care advocate who speaks and provides workshops for cancer survivors and professionals including being a spokesperson for the American Cancer Society and gives radio and television interviews., More information is found at: