Archive for the ‘research’ Category

New study finds optimistic people sleep better and longer.

Wednesday, August 14th, 2019

A new study published in the journal Behavioral Medicine concluded that young and middle aged adults who are most optimistic tend to be better sleepers. Over 3,500 subjects age 32 to 51 from 4 major cities in the USA were included in the sample. In the study optimism was measured using a 10-item survey which asked them to rate on a 5 point scale how much they agreed with positive statements such as “I’m always optimistic about my future” and included negatively worded sentences such as “I hardly expect things to go my way.” Scores on the survey questionaire ranged from six (least optimistic) to 30 (most optimistic). Subjects completed the survey two times  five years apart. Questions included overall sleep quality and duration during the past month, symptoms of insomnia, difficulty falling asleep,and the number of hours of actual sleep they obtained. A subset of the study  wore activity monitors for three consecutive nights including two week nights and one weekend night. The monitors were worn two time one year apart.

Researchers reported “Results from the study revealed a significant associations between optimism and various characteristics of self reported sleep  after adjusting for a wide range of variables, including socio-demographic characteristics, health conditions and depressive symptoms.”  They found that with each standard deviation increase regarding optimism scores there was a 78% higher odds of reporting very good sleep quality. In addition, those who had greater levels of optimism were more likely to report they got adequate sleep usually six to nine hours nightly and were also 74% more likely to report no symptoms of insomnia and to report less daytime sleepiness. A 2016 study found that about 1/3 of adults in the USA fail to get adequate sleep increasing their risk of chronic illnesses. Researchers stated “The lack of healthy sleep is a public health concern, as poor sleep quality is associated with multiple problems, including higher risks of obesity, hypertension and all cause mortality.” “Dispositional optimism–the belief that positive things will occur in the future-has emerged as a psychological asset of particular salience for disease-free survival and superior health.” These findings bolster previous findings of the researchers in which they found optimists ages 45 to 84 were twice as likely to have ideal heart health than those will least optimism.

Glioblastoma Research Shows Tumor Cell Death in Cell and Animal Studies Using Antihistamines.

Wednesday, July 17th, 2019

A new study published in EMBO Molecular Medicine Journal concluded that “antihistamines and other drugs that increase the permeability of the lysomal membrane can be considered as an enhancing therapy for patiets with glioblastoma alongside established treatments.” In the research they found that “glioblastoma cells depend upon the expression of a gene which produces the MDGI protein (small fatty acid binding protein). Inhibiting of this gene results in the death of the tumor cells.” The absence of MDGI causes instability in the membranes of lysosomes, cleaning organelles found inside tumor cells, and in turn, resulting in the leakage of acidic and proteolytic enzymes contained in the lysosomes into the cytoplasm, initiating cell death. Reasearchers said their research “demonstrates that MDGI  is a key factor regulating and maintaining the structure of the lysosomal membrane. This is the first gene found to regulate the stability of the membrane.”  Their results are especially interesting because they found that cell death caused by leakage in the lysosomes of glioblastoma can be activated by using drugs that cross the blood-brain barrier” and in this study they used the antihistamine clemastine.

In cell cultures the antihistamine in lysosome-initiated cell death in glioblastoma cells were at concentrations that has no significant effect on healthy cells of different types.  In mouse models it was effective in reducing the spread of brain tumors and improving the survival rates of the animals. In the most invasive brain tumor model, the antihistamine resulted in the disappearance of the entire tumor.

 

 

 

How Much Coffee is too Much?

Wednesday, July 10th, 2019

 

A new study published in the American Journal of Clinical Nutrition concluded that drinking 6 or more cups of coffee daily may be detrimental to your lealth by increasing your risk of heart disease by up to 22%. This is the first study to study the upper limits of coffee caffeine and heart disease. In the study 347,077 participants from the United Kindom Biobank, aged 37 to 73 were evaluated in terms of the risk of cardiovascular disease in line with coffee consumption and genetic variations by focusing on the ability of the caffeine-metabolizing gene (CYP1A2) to better process caffeine. Researchers concluded that despite carriers of the fast processing gene variation being 4 times quicker at metabolizing caffeine, the research did not support the belief that these people could safely consume more caffeine, more frequently withlout detrimental health effects.   Thus, moderation in coffee consumption is need for heart health.

Some Breast Cancer Patients Benefit from Tart Cherry That Reduced Joint Pain, and Sore Muscles

Wednesday, July 3rd, 2019

A new study reported in Science Daily concluded that tart cherry decreases joint pain and sore muscles in some breast cancer patients by reducing the musculoskeletal effects of aramatrase inhibitors. These inhibitors are a standard treatment for hormone receptive-positive breast cancer in postmenopausal women and help prevent recurrence by inhibiyting the action of amomatasew that is an enzymew that converts androgens to estrogens. Almopst half of women who use this treatment have joint and muscle pain that can be debilitating and may cause patients to stop treatment.

In the random, double-bind study women were plaqced in a group that received 1 ounce of tart cherry concentrate in 8 ounces of water dailyfor 6 weeks with a group who received a placebo. All had stage 1,2,3 non-metastatic breast cancer.  The study continued through May 2016 to August 2018 and 60 patients were enrolled.  Patients documented their pain intensity at the start of the study, weekly and at the end of the study. Patients who completed the study reported a 34.7% mean decrease in pain compared to 1.4% in the placebo group.  Recearchers say the flavonoids and anthocyanins in the tart cherry have an anti-inflammatory properties that may play a role in reducing the side effects observed. There was a statistical significant difference in the pain levels experienced by patients in the group that received the tart cherry.

Christian Wilde an Author/Researcher Focuses on Tumeric/Disease Research

Sunday, March 17th, 2019

My guest this week was Christian Wilde an author/researcher who has appeared as a favorite guest on hundreds of radio shows and has been a medical ‘go to’ commentator over 106 times on George Noory’s number 1 international radio show airing to millions of nightly listeners in the US and Canada, Armed Forces Radio, Sirius and computers worldwide. as 95 other nationally syndicated radio shows.

He has authored two landmark books, Hidden Causes of Heart Attack and Stroke and Miracle Stem Cell heart Repair. He also authors the Christian Wilde Stem Cell and Turmeric Research Report covering more than 87 catastrophic diseases.

The author’s work has been supported by the Directors of stem cell research, cardiovascular disease and regenerative medicine at 11 major universities, including Columbia, University of Utah, Minnesota and UCSD. He has been a voice for adult stem cell research, documenting the progress since 2002.

Before his endeavors into the medical arena, Christian was an independent song writer and record producer for Warner Bros. Columbia, Capitol/EMI, United Artists and MCA/UNI records. His current 14 song CD as a singer/songwriter is Journey On Hold.

He recently received the “Excellence in New Health Product Innovation” Award in Cambridge, Maryland at the Emord & Associates 10th year Gala as well as an award “For Inventing Novel and Effective Products that Enhance Health and Life.”

More information on his website  https://www.myheartbook.com/pages/christians-bio    

Enjoy the Interview Below:

 

 

Childhood Cancer Survivors at Increased Risk of Adult Heart Problems

Wednesday, March 28th, 2018

A new study published in the European Heart Journal concluded that survivors of childhood cancer are at increased risk of suffering prematurely from cardiovascular disease in adulthood.

In the study survivors of childhood cancer were followed into adulthood and compared with a non cancer sample from the general population,. The study population as adults were at higher risk of high blood pressure and dyslipidaemia (unusually high levels of cholesterol and other fats in the blood)  These conditions appeared 6 and 8 years earlier than in the general population controls. In addition, the childhood survivors had a nearly two fold increase risk of cardiovascular diseases such as congestive heart failure, and venous thromboembolism. Cardiovascular  disease was found in 4.5% of survivors and occurred in the majority before the age of 40 and nearly eight years earlier than the general population control.

Between October 2013 and February, 2016, a total of 951 adult long term survivors of childhood cancer underwent a clinical exam that included assessing factors that might put them at higher risk of cardiovascular disease, such as high blood pressure, and dyslipidaemia. Their medical history such as whether or not they smoked and whether there were family members with a history of cardiovascular disease was examined. The survivors ages range from 23 to 48 at follow up and the general population control numbered 15,000. Researchers concluded “Our results show that these survivors of childhood cancer have a substantially elevated burden of prematurely occurring traditional cardiovascular risk factors and cardiovascular disease.” Many of the survivors were unaware of their cardiovascular risk prior to the study.

The most common cardiovascular risk factors identified were high blood pressure and dyslipidaemia that involved 23% and 28% respectively whereas diabetes was only found in 2%. These conditions also occurred earlier than in the general population control.  At least one cardiovascular disease was found in 4.5% of the survivors and tthe most common was that affected 2%. venous thromboembolism.  In addition, 1.2% had congestive heart failure, 0.5% had stroke or peripheral artery disease,, and 0.4% had atrial fibrillation.

Researchers said treatment of childhood cancer include chemotherapy and radiation can affect the heart causing temporary or permanent damage to heart cells and blood vessels. Further research is planned.

 

Dr William Bengston cures Cancer in Mice with Energy Healing.

Sunday, March 25th, 2018

Dr William F. Bengston is a professor of statistics and research methods, and the President of the Society for Scientific Exploration, an international group of scientists and researchers who study anomalies.  Dr. Bengston has been researching anomalous healing for over thirty five years, and has numerous publications in scientific journals.  He has also lectured widely in the U.S., Canada, and Europe.

His memoir, The Energy Cure, is published by Sounds True.  Bill’s research has produced the first successful full cures of transplanted mammary cancer and methylcholanthrene induced sarcomas in mice by energy healing techniques that he helped to develop.  He has also investigated assorted correlates to healing such as EEG and fMRI entrainment, and geomagnetic micropulsation anomalies in healing space.  His current research focuses on the attempt to record and store healing in both biological and physical systems, and to be able to reproduce the healing effect without the healer.

Enjoy the Interview below:

 

 

Dr Terry Wahl Overcome Debilitating Effects of Multiple Sclerosis

Sunday, March 11th, 2018

 

 Dr. Terry Wahls is a clinical professor of medicine at the University of Iowa where she conducts clinical trials. She is also a patient with secondary progressive multiple sclerosis, which confined her to a tilt-recline wheelchair for four years. Dr. Wahls restored her health using a diet and lifestyle program she designed specifically for her brain and now pedals her bike to work each day. She is the author of The Wahls Protocol: How I Beat Progressive MS Using Paleo Principles and Functional Medicine, The Wahls Protocol: A Radical New Way to Treat All Chronic Autoimmune Conditions Using Paleo Principles (paperback), and the cookbook The Wahls Protocol Cooking for Life: The Revolutionary Modern Paleo Plan to Treat All Chronic Autoimmune Conditions            

You can learn more about her work from her website, www.terrywahls.com. She conducts clinical trials that test the effect of nutrition and lifestyle interventions to treat MS and other progressive health problems. She also teaches the public and medical community about the healing power of the Paleo diet and therapeutic lifestyle changes that restore health and vitality to our citizens. She hosts a Wahls Protocol Seminar every August where anyone can learn how to implement the Protocol with ease and success. Follow her on Facebook (Terry Wahls MD) and on Twitter at @TerryWahls.    Learn more about her MS clinical trials by reaching out to her team MSDietStudy@healthcare.uiowa.edu.

Clinical trials in which her team is participating

The links to our Nations MS Society funded research

http://www.nationalmssociety.org/About-the-Society/News/National-MS-Society-and-University-of-Iowa-Launch

Two studies in Bastyr University that are asking patients with MS or Parkinson’s disease about whether they are following the Wahls diet.

These studies are based upon surveys that are completed every 6 months and do not require visits to the study site. Multiple sclerosis

http://bastyr.edu/research/studies/complementary-alternative-medicine-care-multiple-sclerosis-cam-care-ms

Parkinson’s study
http://bastyr.edu/research/studies/complementary-alternative-medicine-care-parkinsons-disease-cam-care-pd

Enjoy the Interview Below:

 

 

 

 

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Chemo-Brain is part of Cancer Progression and Chemotherapy

Friday, December 1st, 2017

Chemo brain or chemo fog are the memory and thinking problems experienced by cancer survivors are not just the result of chemotherapy but may start as the tumor forms and develops  before chemo was used according to a new study published in the journal Neuroscience.  Researchers found that female mice with a form of breast cancer demonstrat4ed impaired performance on learning and memory tests before chemotherapy drugs were used., They said “Our work isolated that the cancer is responsible for some of the memory and thinking complaints experienced by cancer survivors, and that drug therapy adds to the problem.” “Both factors independently effect brain function in different ways, which can lead to the development of other psychological disturbances, such as anxiety and depression.” Researchers said as many as 65on. taking longer to complete tasks, and difficulty multitasking.

Progression of tumor and later chemotherapy lead researchers to the identification of three different brain changes. 1)The combination of tumor growth and chemotherapy led to shrinkage of . While the tumor is developing, the body’s immune system releases cytokines  to inhibit the cancer development. Researchers found this reaction caused in the brains nervous system impairing its function. 2) Chemotherapy limited the production of new brain cells in the regions responsible for memory function which lead to a loss of memory. 3)  The combination of tumor growth and chemotherapy lead to shrinkage in brain regions that are important for learning and memory.

the study involved female mice, half with cancer and the other half without. Learning and memory tests were administered initially to determine the the impact of the tumor on the brain. After this mice were either given chemo or a saline solution (control). .Tests were again administered plus some additional ones. After testing was completed researchers brain images, tissue, and blood samples were used to analyze changes in brain structure and cytokinase activity mentioned earlier Before treatment mice with tumors performed less well on memory and learning tests than mice without tumors. After chemotherapy the performance of cancerous mice worsened, and the non-cancerous mice also showed sign’s of deterioration     Further research is planned..

 

Drinking Coffee may Increase Life Span.

Wednesday, November 29th, 2017

 

A review of over 200 studies published in the British Medical Journal suggest that frinking three or four cups of coffee daily is linked to a lower risk of early death  and getting heart disease  than not drinking coffee. The researcher said drinking coffee “is more likely to to benefit health than harm it” for a range of health outcomes such as cancer, diabetes, kiver dusease and dementia. Exceptioms are women who are pregnant and those who suffer fractures.

No firm conclusions can be drawn because the majority of studies were observational but back up other recent studies. Thus, they say “with the exception of pregnancy and women at risk of fractures “coffee drinking appears safew within usual patterns of consuymption” and could be tested further inrandomized studies.

In the study the largest reduction in death was related to drinking 3 cups a day compared with non-coffee drinkers. Drinking moire than 3 cups daily were not associatioted with harm but were not as beneficial. Beneficial effects related to a lower risk of several cancers including prostate, endometrial, skin, and liver, as well as tyoe 2 diabete, gall stones, and gout. The greatest benefit weas seen for liver disease such as cirrhosis. Additional benefits were seen for Parkinson disease, depression, and Altzheimers disease. Researchers recommended against starting drinking coffee for health benefits until the evidence of an association is stronger.