Archive for the ‘research’ Category

Some Heart Problems May be Related to A Commonly Used Antibiotics

Wednesday, September 25th, 2019

A new study published in the Journal of the American College of Cardiology  concluded that current users of fluoroquinolone antibiotics, such as Ciprofloxacin or Cipro, have a 2.4 times greater risk of developing aortic or mitral regurgitation compared to patients taking amoxicillin, a different type of  antibiotic. This greater risk occurs within 30 days of use.  Recent studies have also liked the same class of antibiotics to other heart problems. Some physicians prefer tis class of antibiotics over others bewcvause of their broad spectrum of antibacterial activities and high oral absorption, which is as effective as intravenous treatment.

For the study researchers analyzed data from the U S Food  and Drug Administration’s adverse reporting system and a massive private insurance health data claims database in the U S that collects demographics, drug identification, dose prescribed, and treatment duration.  Researchers identified 12,505 cases of valvular regurgitation with 125,020 case-controlled subjects of move than nine million patients in a random sample.  They defined current floroquinolone exposure as an active prescription or 30 days prior to ther adsverse event, recent exposure as within 31 to 60 days, and past exposure as within 61 to 365 days prior to an incident. Flouroquinolone was compared with amoxicillin and azithromycin.  Results shjowed that the risk of aortic and mityral regurgitation, blood backflow into the heart, is highest with current use, followed by recent use. The found no increased risk aortic or mitral regurgitation with past use.

 

Athletes are at risk for skin cancer.

Wednesday, September 4th, 2019

At a recent conference of the Physiological Society’s Extreme Environmental Psychology a researcher said athletes ranging from hikers, to tenn is to runnersexceed the recommended ultraviolet exposure limit by up to eight-fold during the summer and fall seasons. Even though exercise is assocoated with a reduced risk of cancer, skin cancer is the exception. For malignant skin cancers, those in the 90th percentile of exercise have an increased risk of cancer than those in the 10th percentile. And outdoor activities have consistently demonstrated an elevated risk for skin cancer in research studies.

Ultraviolet radiation is categorized byy wavelengths as UV- (320-400 nm) that is about 95% of radiation reaching the earth; UV-B (290-320 nm) whichis about 5% of the radiation reaching earth; and UV-C (200-290 nm). In the skin, the skins blood circulation can be reached by UV-A, whereas most of the UV-B is absorbed by the outer layer of the skin due to its short wavelength.

Responses to untraviolet rays are also affected by skin pigmentation. The bodys ability to create two important substances  are affected by ultraviolet radiation. These are vitamin D and folate whih are especially important in pregnancy and early childhood development and UV radiation helps vitamin D synthesis and causes folate to break away. Some believe early human populations living in Africa, evolved skin pigmentation to protect themselves from folate degradation and as later populations moved away from the equator skin depigmentation allowed for higher levels of vitamin D synthesis. The researcher concluded with “Sun protection in athletes is especially important as multiple studies demonstrate an elevated risk of skin cancer for those who regularly participate in outdoor sports or exercise. Suprisingly, fewer than 25% of surveyed athletes reported regular use of sunscreen,m so there is clearly more awarenewss-raising that needs to be done.”

Colon cancer and colitis worsen as a result of frying oil consumption in mouse studies.

Wednesday, August 28th, 2019

In a new study published in Cancer Prevention Research researchers concluded that feeding frying oil to mice exaggerated colonic inflammation, enhanced tumor growth and worsened gut leakage, spreading bacteria or toxic bacterial products into the blood stream. Researchers said their research does not say that frying oil can cause cancer but that it suggests fried foods may exacerbate and advance conditions of the colon. “If somebody has IBD or colon cancer and they eat this kind of food, there is a chance it will make the diseases more aggressive.”

In their study researchers used a real-world sample of canola oil, in which falafel had been cooked at 325 degrees farenheit in a standard commercial fryer at a restaurant in Massachusetts. The oil had been analyzed for an array of chemical reactions during the frying process and characterized according to a fatty acid profile, the level of free fatty acids and the status of oxidation.  A combination of the frying oil and fresh oil was added to the powdered diet of one group of mice and the control was fed the powder with only fresh oil mixed in. Rersearches said “We tried to mimic the human being’s diet.” They found that adding the frying oil to the diet worsened colonic inflammation, colon tumor growth, and gut leakage. For example, tumor growth doubled in size from the control to study groups.

To determine if oxidation of polmunsaturated fatty acids, which occur when the oil is heated, is instrumental in the inflammattory effects, polar compounds from the frying oil was isolated and fed to the mice.  Results were similar to those from the experiment in which mice were fed frying oil. This suggested that the polswar compounds mediated the inflammatory effects. Researchers cautioned tyhat more research is needed but suggested people with inflammatory bowel disease eat less friend foods.

New study finds optimistic people sleep better and longer.

Wednesday, August 14th, 2019

A new study published in the journal Behavioral Medicine concluded that young and middle aged adults who are most optimistic tend to be better sleepers. Over 3,500 subjects age 32 to 51 from 4 major cities in the USA were included in the sample. In the study optimism was measured using a 10-item survey which asked them to rate on a 5 point scale how much they agreed with positive statements such as “I’m always optimistic about my future” and included negatively worded sentences such as “I hardly expect things to go my way.” Scores on the survey questionaire ranged from six (least optimistic) to 30 (most optimistic). Subjects completed the survey two times  five years apart. Questions included overall sleep quality and duration during the past month, symptoms of insomnia, difficulty falling asleep,and the number of hours of actual sleep they obtained. A subset of the study  wore activity monitors for three consecutive nights including two week nights and one weekend night. The monitors were worn two time one year apart.

Researchers reported “Results from the study revealed a significant associations between optimism and various characteristics of self reported sleep  after adjusting for a wide range of variables, including socio-demographic characteristics, health conditions and depressive symptoms.”  They found that with each standard deviation increase regarding optimism scores there was a 78% higher odds of reporting very good sleep quality. In addition, those who had greater levels of optimism were more likely to report they got adequate sleep usually six to nine hours nightly and were also 74% more likely to report no symptoms of insomnia and to report less daytime sleepiness. A 2016 study found that about 1/3 of adults in the USA fail to get adequate sleep increasing their risk of chronic illnesses. Researchers stated “The lack of healthy sleep is a public health concern, as poor sleep quality is associated with multiple problems, including higher risks of obesity, hypertension and all cause mortality.” “Dispositional optimism–the belief that positive things will occur in the future-has emerged as a psychological asset of particular salience for disease-free survival and superior health.” These findings bolster previous findings of the researchers in which they found optimists ages 45 to 84 were twice as likely to have ideal heart health than those will least optimism.

Glioblastoma Research Shows Tumor Cell Death in Cell and Animal Studies Using Antihistamines.

Wednesday, July 17th, 2019

A new study published in EMBO Molecular Medicine Journal concluded that “antihistamines and other drugs that increase the permeability of the lysomal membrane can be considered as an enhancing therapy for patiets with glioblastoma alongside established treatments.” In the research they found that “glioblastoma cells depend upon the expression of a gene which produces the MDGI protein (small fatty acid binding protein). Inhibiting of this gene results in the death of the tumor cells.” The absence of MDGI causes instability in the membranes of lysosomes, cleaning organelles found inside tumor cells, and in turn, resulting in the leakage of acidic and proteolytic enzymes contained in the lysosomes into the cytoplasm, initiating cell death. Reasearchers said their research “demonstrates that MDGI  is a key factor regulating and maintaining the structure of the lysosomal membrane. This is the first gene found to regulate the stability of the membrane.”  Their results are especially interesting because they found that cell death caused by leakage in the lysosomes of glioblastoma can be activated by using drugs that cross the blood-brain barrier” and in this study they used the antihistamine clemastine.

In cell cultures the antihistamine in lysosome-initiated cell death in glioblastoma cells were at concentrations that has no significant effect on healthy cells of different types.  In mouse models it was effective in reducing the spread of brain tumors and improving the survival rates of the animals. In the most invasive brain tumor model, the antihistamine resulted in the disappearance of the entire tumor.

 

 

 

How Much Coffee is too Much?

Wednesday, July 10th, 2019

 

A new study published in the American Journal of Clinical Nutrition concluded that drinking 6 or more cups of coffee daily may be detrimental to your lealth by increasing your risk of heart disease by up to 22%. This is the first study to study the upper limits of coffee caffeine and heart disease. In the study 347,077 participants from the United Kindom Biobank, aged 37 to 73 were evaluated in terms of the risk of cardiovascular disease in line with coffee consumption and genetic variations by focusing on the ability of the caffeine-metabolizing gene (CYP1A2) to better process caffeine. Researchers concluded that despite carriers of the fast processing gene variation being 4 times quicker at metabolizing caffeine, the research did not support the belief that these people could safely consume more caffeine, more frequently withlout detrimental health effects.   Thus, moderation in coffee consumption is need for heart health.

Some Breast Cancer Patients Benefit from Tart Cherry That Reduced Joint Pain, and Sore Muscles

Wednesday, July 3rd, 2019

A new study reported in Science Daily concluded that tart cherry decreases joint pain and sore muscles in some breast cancer patients by reducing the musculoskeletal effects of aramatrase inhibitors. These inhibitors are a standard treatment for hormone receptive-positive breast cancer in postmenopausal women and help prevent recurrence by inhibiyting the action of amomatasew that is an enzymew that converts androgens to estrogens. Almopst half of women who use this treatment have joint and muscle pain that can be debilitating and may cause patients to stop treatment.

In the random, double-bind study women were plaqced in a group that received 1 ounce of tart cherry concentrate in 8 ounces of water dailyfor 6 weeks with a group who received a placebo. All had stage 1,2,3 non-metastatic breast cancer.  The study continued through May 2016 to August 2018 and 60 patients were enrolled.  Patients documented their pain intensity at the start of the study, weekly and at the end of the study. Patients who completed the study reported a 34.7% mean decrease in pain compared to 1.4% in the placebo group.  Recearchers say the flavonoids and anthocyanins in the tart cherry have an anti-inflammatory properties that may play a role in reducing the side effects observed. There was a statistical significant difference in the pain levels experienced by patients in the group that received the tart cherry.

Christian Wilde an Author/Researcher Focuses on Tumeric/Disease Research

Sunday, March 17th, 2019

My guest this week was Christian Wilde an author/researcher who has appeared as a favorite guest on hundreds of radio shows and has been a medical ‘go to’ commentator over 106 times on George Noory’s number 1 international radio show airing to millions of nightly listeners in the US and Canada, Armed Forces Radio, Sirius and computers worldwide. as 95 other nationally syndicated radio shows.

He has authored two landmark books, Hidden Causes of Heart Attack and Stroke and Miracle Stem Cell heart Repair. He also authors the Christian Wilde Stem Cell and Turmeric Research Report covering more than 87 catastrophic diseases.

The author’s work has been supported by the Directors of stem cell research, cardiovascular disease and regenerative medicine at 11 major universities, including Columbia, University of Utah, Minnesota and UCSD. He has been a voice for adult stem cell research, documenting the progress since 2002.

Before his endeavors into the medical arena, Christian was an independent song writer and record producer for Warner Bros. Columbia, Capitol/EMI, United Artists and MCA/UNI records. His current 14 song CD as a singer/songwriter is Journey On Hold.

He recently received the “Excellence in New Health Product Innovation” Award in Cambridge, Maryland at the Emord & Associates 10th year Gala as well as an award “For Inventing Novel and Effective Products that Enhance Health and Life.”

More information on his website  https://www.myheartbook.com/pages/christians-bio    

Enjoy the Interview Below:

 

 

Childhood Cancer Survivors at Increased Risk of Adult Heart Problems

Wednesday, March 28th, 2018

A new study published in the European Heart Journal concluded that survivors of childhood cancer are at increased risk of suffering prematurely from cardiovascular disease in adulthood.

In the study survivors of childhood cancer were followed into adulthood and compared with a non cancer sample from the general population,. The study population as adults were at higher risk of high blood pressure and dyslipidaemia (unusually high levels of cholesterol and other fats in the blood)  These conditions appeared 6 and 8 years earlier than in the general population controls. In addition, the childhood survivors had a nearly two fold increase risk of cardiovascular diseases such as congestive heart failure, and venous thromboembolism. Cardiovascular  disease was found in 4.5% of survivors and occurred in the majority before the age of 40 and nearly eight years earlier than the general population control.

Between October 2013 and February, 2016, a total of 951 adult long term survivors of childhood cancer underwent a clinical exam that included assessing factors that might put them at higher risk of cardiovascular disease, such as high blood pressure, and dyslipidaemia. Their medical history such as whether or not they smoked and whether there were family members with a history of cardiovascular disease was examined. The survivors ages range from 23 to 48 at follow up and the general population control numbered 15,000. Researchers concluded “Our results show that these survivors of childhood cancer have a substantially elevated burden of prematurely occurring traditional cardiovascular risk factors and cardiovascular disease.” Many of the survivors were unaware of their cardiovascular risk prior to the study.

The most common cardiovascular risk factors identified were high blood pressure and dyslipidaemia that involved 23% and 28% respectively whereas diabetes was only found in 2%. These conditions also occurred earlier than in the general population control.  At least one cardiovascular disease was found in 4.5% of the survivors and tthe most common was that affected 2%. venous thromboembolism.  In addition, 1.2% had congestive heart failure, 0.5% had stroke or peripheral artery disease,, and 0.4% had atrial fibrillation.

Researchers said treatment of childhood cancer include chemotherapy and radiation can affect the heart causing temporary or permanent damage to heart cells and blood vessels. Further research is planned.

 

Dr William Bengston cures Cancer in Mice with Energy Healing.

Sunday, March 25th, 2018

Dr William F. Bengston is a professor of statistics and research methods, and the President of the Society for Scientific Exploration, an international group of scientists and researchers who study anomalies.  Dr. Bengston has been researching anomalous healing for over thirty five years, and has numerous publications in scientific journals.  He has also lectured widely in the U.S., Canada, and Europe.

His memoir, The Energy Cure, is published by Sounds True.  Bill’s research has produced the first successful full cures of transplanted mammary cancer and methylcholanthrene induced sarcomas in mice by energy healing techniques that he helped to develop.  He has also investigated assorted correlates to healing such as EEG and fMRI entrainment, and geomagnetic micropulsation anomalies in healing space.  His current research focuses on the attempt to record and store healing in both biological and physical systems, and to be able to reproduce the healing effect without the healer.

Enjoy the Interview below: