Posts Tagged ‘asbestosis’

Does the Combination of Asbestos Exposure, Asbestosis, and Smoking Increase the Risk of Lung Cancer?

Wednesday, April 17th, 2013

logo1267406_mdIn an online publication of The American Thoracic Society’s American Journal of Respiratory and Critical Care medicine researchers concluded that the chances of developing lung cancer associated with exposure to asbestos, asbestosis, and smoking are dramatically increased when these three risk factors are combined, and smoking cessation significantly reduces the risk of developing lung cancer after long term asbestos exposure. Researchers said “In our study of a large cohort of asbestos-exposed insulators and more than 50,000 non-exposed controls, we found that each individual risk factor was associated with increased risk of developing lung cancer, while the combination of all three risk factors increased the risk of developing lung cancer almost 37-fold.” Results showed that in non-smokers asbestos exposure increased the risk of dying from lung cancer 5.2 fold, while the combination of smoking and asbestos exposure increased the death rate more than 28-fold and asbestosis increased the risk of developing lung cancer among asbestos-exposed subjects in both smokers and non-smokers, with the death rate from lung cancer increasing 36.8-fold among asbestos-exposed smokers with asbestosis. In addition, among insulators who quit smoking, lung cancer rates dropped in the ten years following smoking cessation from 177 deaths per 10,000 among current smokers to 90 per 10,000  among those who quit. The lung cancer rates among those who quit more than 30 years earlier were similar to those who never smoked.