Posts Tagged ‘bowel cancer’

Will Healthy Behaviors Reduce the Risk of Bowel Cancer?

Wednesday, October 22nd, 2014

New research published in open access journal BMC Medicine  concluded that adopting a combination of 5 healthy behaviors is associated with a reduction in bowel cancer. Quantifying the impact of combining multiple lifestyle behaviors on the risk of developing bowel cancer they found the impact stronger in men than women. Previous research has found a link beween life style and colon cancer but have focused on single characteristics such as eating red meat. This study focused on multiple characteristics.

Data were analyzed from 347,237 men and women from 10 countriesin Europe as part of the European Prospective Investigation into Cancer and Nutrition (EPIC). Over 12 years there were 3,759 cases of bowel cancer. The healthy lifestyle index included a) a healthy weight, b) low abdominal fat, c) participating in regular exercise, d) not smoking and limiting alcohol, and e) a diet high in fruits, vegetables, fish, yogurt, nuts and seeds, and foods rich in fiber, and a low amount of red and processed meat, A scoring system was developed around these behaviors and a cumulative score was developed for each individual in the study. They found that the more healthy life style factors the cohort adopted, the lower their risk of bowel cancer , Compared to those who had one healthy lifestyle pattern, those with two, three, four or all five behaviors had a 13%, 21%, 34%, and 37% lower rate of developing bowel cancer respectively. Noting a difference between men and women they concluded that up to 22% of the cases in men and 11% of the cases in women would have been prevented if all five lifestyle behaviors had been followed.

Bowel Cancer Risk May be Reduced by High Levels of Good Cholesterol

Wednesday, March 16th, 2011


Recent research published online in Gut concluded that high levels of “good” HDL cholesterol may cut the risk of bowel cancer and this association is independent of other potentially cancer-inducing markers of inflammation in the blood.

Using participants in the European Prospective Investigation into Cancer and Nutrition Study (EPIC) that tracks the impact of nutrition on the development of cancer in over 1/2 million Europeans the researchers matched around 1200 subjects who developed bowel (779 people) and rectal (459 people) cancers with 1,200 controls who were of the same age, gender, and nationality.

Initial blood samples and nutritional data for the subjects and controls were compared for differences. Analysis show that those with the highest levels of HDL cholesterol and another blood fat, apolipoprotein A (apoA) -a component of HDL cholesterol had the lowest risk of developing cancer of the bowel. Although changes in HDL and apoA had no effect on the risk of rectal cancer, each rise of 16.6 mg/dl in HDL reduced the risk of bowel cancer by 22% and each rise of apoA reduced the risk of bowel cancer by 18% after accounting for causal factors of lifestyle, diet, and weight. After eliminating subjects monitored in the study for only two years the levels of HDL continued to show a reduced risk of bowel cancer but apoA levels did not.

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