Posts Tagged ‘breast cancer risk’

Increased Breast Cancer risk in Women Related to Night Lights

Wednesday, August 23rd, 2017

 

A new study published in Environmental Health Perspectives concluded that women who live in areas with higher levels of outdoor lights at night may be at a greater risk of breast cancer than women in areas of lower light,  The link was stronger among women who worked nights  Previous studies have found that exposure to light at night may lead to decreased levels of the hormone melatonin that can effect our circadian rhythms and lead to breast cancer.

In the study nearly 110,000 women enrolled in the Nurses Health Study II between 1989 and 2013 were evaluated. Data on night satellite images of earth residential addresses were linked to for each participant and also considered night work or not. Data on health and socioeconomic factors were also considered.  Women exposed to the upper level of light at night (the top fifth) had an estimated 14% increase in breast cancer during the study period than those in the lowest fifth.  As the light increased outside so did the risk of breast cancer.

This relationship was found only among women who were premenopausal and those who were current or past smokers. In addition, the link was stronger among women who worked nights. The researchers said further research is needed.

 

Does Working Nights Increase Breast Cancer Risk?

Wednesday, October 12th, 2016

 

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A new study published in the Journal of the National Cancer Institute concluded that working nights has little or no effect on a woman’s breast cancer risk despite a review in 2007 by the International Agency for Research on Cancer classifying night work as disrupting the body clock and a probably cause of cancer. In 2007 there was limited research on breast cancer risks in humans so the classification was based primarily on lab and animal studies.

The recent study followed 1.4 million women working night shift in 10 studies to determine if they developed breast cancer. Those who worked night shift for 20 to 30 years had no increased risk of breast cancer when compared with w2omen who had never worked night shift. Researchers found the incidence of breast cancer essentially the same for women who did not work night shift or worked night shift for several decades. The combined relative risk from all 10 studies together was 0.99   for any night work, 1.01 for 20 or more years night shift work, and 1.00 for 30 or more years night shift work. Researchers said “Breast cancer is the most common cause in women so it is vital for us to fund work in this area to establish if there is a link to night work.”  The also said ” This study has shwn that night dhift work, including long-term shift work, has little or no effect on breast cancer incidence in women. However, there are a number of other known risks with shift work that employers must take into consideration when protecting their workers’ health and safety.,” These include  “maintaining a healthy weight, drinking less alcohol, and being active.”

Can Tomatoes in Your Diet Lower Breast Cancer Risk?

Wednesday, January 1st, 2014

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A new study to be published in The Journal of Endocrinology & Metabolism concluded that a tomato-rich diet may help protect at-risk postmenopausal women from breast cancer. In the longitudinal cross- over study a group of 70 postmenopausal women were examined for the effects of both tomato and soy-rich diets. Women ate tomato products containing at least 25 milligrams of lycopene daily for 10 weeks. For a separate 10 week period, they ate at least 40 grams of soy protein daily. For two weeks before each test period the women were asked to refrain from eating both tomatoes and soy products.

When they followed the tomato-rich diet the level of adiponectin, a hormone involved in regulating blood sugar and fat levels, climbed 9 percent and this was slightly stronger in women who had a lower body mass index. It is known that breast cancer risk increase in postmenopausal women as their body mass index climbs, and these findings found a diet high in tomatoes had a positive effect on the level of hormones that play a role in regulating fat and sugar. Researchers said “The findings demonstrate the importance of obesity prevention…..Consuming a diet rich in tomatoes had a larger impact on hormone levels in women who maintained a healthy weight.”  On the other hand, the soy diet was linked to a reduction in adiponectin levels in the women in the study/

Can Working Night Shifts Increase Your Breast Cancer Risk?

Wednesday, July 10th, 2013

logo1267406_md New research published in online Occupational and Environmental Medicine concluded that working night shifts for 30 or more years doubles the risk of breast cancer and is not confined to nurses. Researchers assessed 1134 women with breast cancer and 1179 without the disease but of the same age to assess whether working night shifts increased the risk of breast cancer. Women who did various jobs were asked about their shift work over their entire work period and hospital records were used to determine tumor types. Around one in three women in both groups had worked night shift and results showed that those who worked up to 14 years or between 15 and 29 years did not have an increased risk of developing breast cancer.  However, those working 30 or more years were twice as likely to develop breast cancer after accounting for potentially causal factors regardless of being in health care or not,. The numbers of breast cancer cases involved in these results were small, however.  Factors accounting for these results may include melatonin, sleep disturbances, upset body rhythms, vitamin D and lifestyle differences. . The authors concluded “As shift work is necessary for many occupations, understanding which specific patterns increase breast cancer risk, and how night shift work influences the pathway to breast cancer is needed.?

Can Eating Fish Lower the Risk of Breast Cancer?

Wednesday, July 3rd, 2013

logo1267406_mdA new study published in the British Medical Journal concluded that a high intake of fatty acids found in fish is associated with a 14% reduction in the risk of breast cancer later in life.

The researchers  investigated the association between fish and n-3 polyunsaturated fatty acids (n-3 PUFA)  intake and the risk of breast cancer. The n-3 PUFAs include ALA, EPA, DPA, and DHA and are involved in chemical messaging in the brain, helping to regulate blood vessel activity and areas of the immune system. The main dietary source of EPA,DPA and DHA is oily fish, and of ALA is  mainly in nut seeds, and green leafy vegetables.

Researchers reviewed and analyzed the results of 26 studies from the United Sates, Europe and Asia  that involved over 800,000 subjects with over 20,000 breast cancer cases. Findings showed that marine n-3 PUFA was associated with a 14% reduction in breast cancer between the highest and lowest categories of intake with the lowest risk in Asians possibly due to higher fish intake than western countries. Further analysis showed a dose response: for each 0.1 gm per day or 0.1 % energy per day increment of intake of n-3 PUFA from fish there was an associated 5% risk in reduction. To achieve this risk reduction requires 1 to 2 portions weekly  of fish such as salmon, tuna, or sardines. However, no significant protection was found in ALA-the plant based n-3 PUFA.  Researchers concluded “Our present study provides solid and robust evidence that marine n-3 PUFA are inversely associated with risk of breast cancer. The protective effect of fish or individual n-3 PUFA warrents further investigation of prospective studies.”

Further Research on Exercise and Breast Cancer Risk.

Wednesday, July 4th, 2012

Recent research published in early online Cancer concluded that mild or intense  exercise and  either before or after menopause may reduce the risk of breast cancer. However, substantial weight gain many negate these results. This information adds to the existing information on exercise and breast cancer by elaborating on such questions as duration, frequency, and intensity and the influence of body type.

The study included 1,504 women with breast cancer (233 noninvasive and 1,271 invasive) and 1,555 women women without breast cancer who acted as controls. All were between age 20 and 98 years of age.

Results showed that women who exercised during reproductive or postmenopausal years had a reduced risk of developing breast cancer with those exercising 10 to 19 hours a week experiencing the greatest benefit of about 30% reduced risk. Exercise at all levels of intensity reduced the risk of breast cancer and seemed to preferentially reduce the risk of hormone receptor positive breast cancer (ER or PR positive) that is the most common type of breast cancer among American women.  When researchers looked at the joint effects of phy6sical activity, weight gain, and body size, they found that women who were active but who gained a significant amount of weight, especially after menopause, had an increased risk of developing breast cancer indicating that weight gain eliminates the beneficial effect of exercise on breast cancer risk.