Posts Tagged ‘colon cancer’

Is Excess Sugar Linked to Cancer”

Wednesday, February 6th, 2013

logo1267406_mdWhat has long been known by alternative physicians and others who use non-traditional approaches to cancer treatment has not been researched and shown to be true -there is a link between sugar and cancer. In recent research published in Molecular Cell researchers concluded that sustained high levels of sugar, as is found in diabetes, damage our cells and now is shown that it can increase our changes of having cancer.  It was known that in obesity and diabetes the body fails to control, blood sugar levels but less was known about this connection with cancer. But now it is known that the diabetes population has up to double chances to suffer pancreatic or colon cancer risk. This research a key mechanism that links obesity and diabetes with cancer and that is high sugar levels which increase activities of a gene widely implicated in cancer progression.

The researchers were studying how cells in the intestines respondf to sugars and signal the pancreas to release insulin, the key hormone that controls blood sugar levels. Sugars in the intestines trigger cells to release a protein called GIP that enhances insulin release by the pancreas. In this study they showed that the ability of the intestinal cells to secrete GIP is controlled by a protein calledβ-catenin, and its activity is strictly dependent upon sugar levels. The researcher said “We were surprised to realize that changes in our metabolism caused by dietary sugar impact our cancer risk. We are now investigating what other dietary components may influence our cancer risk. Changing diet is one of the easiest strategies that can potentially save a lot of suffering and money.”

Interview with Cancer Survivors Christine Clifford (breast, humorist) and Chris Wark (colon) Now Available.

Sunday, December 9th, 2012

yesterday, Dr Carl O Helvie, host, interviewed Christine Clifford (left) and Chris Wark. Christine is a 19 year breast cancer survivor who is President and CEO of the Cancer Club, author of multiple books, and has raised over $1,000,000 for breast cancer research. More information was presented earlier on this site and can be found at: http://www.cancerclub.com

Chris Wark is a real estate investor and musician who overcome colon cancer and has a website http://www.chrisbeatcancer.com

Enjoy the interview below:

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Can Mistletoe Kill Colon Cancer Cells?

Wednesday, December 5th, 2012

Researchers in Australia concluded that mistletoe has great  potential as an alternative therapy for patients with colon cancer. In the study the researcher compared the effectiveness of three different types of mistletoe extract and chemotherapy on healthy intestinal cells. On of the extracts, from a species known as Fraxini that grows on ash trees, was highly effective against colon cancer cells in cell cultures and was gentler on healthy intestinal cells than chemotherapy. Of significance, Fraxini extract was more potent against cancer cells than the chemotherapy drug. The researcher said “This is an important result because we know that chemotherapy is effective at killing healthy cells as well as cancer cells. This can result in severe side effects for the patient, such as oral mucositis (ulcers in the mouth) and hair loss.” In the study Fraxini mistletoe extract by itself was highly effective at reducing the viability of colon cancer cells and at certain concentrations also increased the potency of chemotherapy against cancer cells. Fraxini was the only one of the mistletoe extracts that demonstrated a reduced impact on health intestinal cells. Further research  is needed to add to this research of mistletoe and colon cancer.

Can Carbohydrates Increase the Risk of Cancer Recurrence Among Colon Cancer Survivors?

Friday, November 16th, 2012

A new study published in the Journal of the National Cancer Institute concluded that colon cancer survivors whose diet is high in complex sugars and carbohydrate-rich foods are far more likely to have a recurrence of the disease than those patients who eat a more balanced diet.

One thousand eleven stage III colon cancer patients who had undergone surgery and follow up chemotherapy for their disease  reported their dietary intake during and six months after the trial.  Researchers tracked the total carbohydrates and glycemic index (a measure of how quickly the blood sugar levels rise after eating particular food), and glycemic load (a measure of the amount of carbohydrate actually consumed) on subjects and looked for a relationship between these measures and recurrence of cancer.

Subjects with the highest dietary levels of glycemic load and carbohydrate intake were found to have an 80 percent increased risk for colon cancer recurrence when compared to those who had the lowest levels. In addition, among subjects who were overweight or obese (a body mass index above 25 kg/m2, the increase was even higher. Researchers say “In light of our and other’s research, we theorize that factors including a high glycemic load may stimulate the body’s production of of insulin. That, in turn, may increase the proliferation of cells and prevent the naturalk cell-death process in cancer cells that have metastasized from their original site.” The researcher concluded “Our study certainly supports the idea that diet can impact the progression of colon cancer, and that patients and their doctors should consider this when making post-treatment plans. But further research is nee4ded to confirm our findings.”

Does Milk Have Cancer-Protecting Properties?

Wednesday, October 10th, 2012

Many cancer survivors and others interesting in health avoid milk and when I had lung cancer in 1974 milk was prohibited on my cancer diet. However, a new study published in the Journal of Dairy Science concluded that lactoferricin4-14  (Lfcin4-14), a milk protein with known health benefits, significantly reduced the growth rate of colon cancer cells over time by prolonging the period of the cell cycle  before chromosomes were replicated and they recently found that treatment with Lfcin4-14 reduced DNA damage in colon cancer cells exposed to ultraviolet (UV) light. Although the differences in the subjects vs controls were small they were significant.

In the study researchers exposed colon cancer cells to UV light that cause DNA damage and then grew the cells in the presence or absence of Lfcin4-14. Using a sensitive technique they evaluated the results in which DNA cells damaged by UV light resembled a comet with a tail and the intensity of the tail compared to the head of the comet indicated the number of DNA breaks. UV light exposure resulted in an increase in the number of comets in colon cancer cells without Lfcin4-14 while those treated with Lfcin4-14 had reduced numbers of comets in UV light exposed cells. The researchers said “Our data suggest that the effects of Lfcin4-14 in prolonging the cell cycle may contribute to the cancer prevention effect of milk. This must be further investigated in different systems. ?

Can Regular Use of Vitamins and Mineral Supplements Reduce the Risk of Colon Cancer?

Wednesday, February 8th, 2012

A new study published in the Canadian Journal of Physiology and Pharmacology concluded that rats given regular multi-vitamin and mineral supplements showed a significantly lower risk of developing colon cancer when exposed to carcinogens.

In the study rats were fed a high-fat diet (20% fat) over a 32 week period and were divided into 6 groups that were exposed to different combinations of supplements and carcinogens: the colon carcinogenesis induced in the study rats has characteristic mimicking human colon cancer. Researchers found that the rats given a high-fat plus low fiber diet and exposed to carcinogens developed precancerous lesions. whereas those given a similar intervention but also given daily multivitamin and mineral supplements, had a significant reduction (84%) in the formation of pre-cancerous lesions and did not develop tumors. The researchers concluded that multivitamin and mineral supplements synergistically contribute to the cancer chemopreventive potential, and hence, regular supplements of multi-vitamins and minerals could reduce the risk of colon cancer.”

How Does Mate Tea act on Colon Cancer Cells?

Friday, February 3rd, 2012

An invitro study published in Molecular Nutrition & Food Research concluded that “caffeine derivatives in mate tea not only induced death in human colon cancer cells, they also reduced important markers of inflammation.” Inflammation can trigger the progression of cancer. In the study, researchers isolated, purified, and then treated human colon cancer cells with caffeoylquinic acid (CQA) from mate tea and as they increased the CQA concentration cancer cells died as a result of apoptosis. In other words, “cancer cells self-destruct because its DNA has been damaged.” The researchers identified the mechanism that led to cell death and have completed a follow up study in which they compare the development of colon cancer in rats that drank mate tea as their only source of water with a control group that drank only water. These results will be published soon.
The researcher concluded “We believe there’s ample evidence to support drinking mate tea for its bioactive benefits especially if you have reason to be concerned about colon cancer. Mate tea bags are available in health food stores and are increasingly available in large supermarkets.”

Bacteria in the Gut and Colon Cancer

Friday, July 2nd, 2010

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Research published in the May/June issue of the journal Gut Microbes suggests that a shift in the balance of the good and bad bacteria in the gut could be associated with colon cancer. Using molecular methods that have evolved to the point where all bacteria in the gut can be identified and characterized the researchers studied biopsies from 45 patients undergoing colonoscopies. They found that there was a higher bacterial diversity and richness in individuals found to have adenomas than in those without these colorectal cancer precursors. A particular group called Proteobacteria was higher than in the controls but it is not clear whether these follow the development of the adenoma or were the cause of the adenoma. Further research is planned in animal models to see if these or other bacteria promote cancer growth. Additional samples from up to 600 patients will be analyzed. The researchers stated “What a great way to address colon cancer–you could know your risk and lower it by eating your yogurt every day.”