Posts Tagged ‘colorectal cancer’

Is Your Risk of Colorectal Cancer Reduced by Eating Fruit and Vegetables?

Friday, December 16th, 2011

A recent research study published in the Journal of The American Dietetic Association concluded that the effects of consuming fruit and vegetables seem to differ depending on the site of origin. Within the proximal and distal colon and that brassica vegetables such as Brussels sprouts, cabbage, cauliflower, and broccoli are associated with a decreased risk of these cancer. However, a lower risk of distal colon cancer was associated with eating more apples, and at the same time an increase of rectal cancer was found to occur with the consumption of fruit juices. The researchers acknowledged the earlier research on diet and colorectal cancer research that was contradictory and believe these results were related to not considering the site of the colorectaL cancer. In a case controlled study, the researchers explored the link between fruit and vegetables and cancers in three different parts of the bowel: proximal colon cancer, distal colon cancer, and rectal cancer. There were 918 subjects with a confirmed colorectal diagnosis and 1021 controls with no history of colorectal cancer. Extensive medical and nutritional questionaires were completed and all participants were assigned a socioecomic status depending upon their address.
Results showed that the consumption of brassica vegetables were associated with a reduced incidence of proximal colon cancer, and both fruit and vegetables seemed to reduce the risk of distal colon cancer. Distal colon cancer risk was significantly reduced with the intake of dark yellow vegetables and apples, but there was an increase risk of rectal cancer associated with the consumption of fruit juice. There was no risk of proximal colon cancer or rectal cancer associated with intakes of total fruit and vegetables. total vegetables or total fruit.

Colorectal Cancer in Women Linked to High Blood Sugar Levels

Wednesday, December 7th, 2011

A new study published in the online edition of the British Journal of Cancer concluded that elevated blood sugar levels are associated with an increase risk of colorectal cancer. Women in the National Institute of Health’s Women’s Health Initiative Study were evaluated for fasting blood sugar and insulin levels before the study as a baseline and several times thereafter over a 12 year period. There were 5,000 women in the study and at the end of the 12 years 81 had developed colorectal cancer. Researchers found that baseline elevated blood sugar levels were associated with an increase colorectal cancer risk. Women in the highest 1/3 of baseline blood sugar levels were almost twice as likely to have developed colorectal cancere as the women at the lowest 1/3 levels. Similar results were found when researchers evaluated repeated blood sugar levels over the time period. There was no association between insulin levels and colorectal risk in the study.

Folic Acid and Colon Cancer

Friday, June 3rd, 2011

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A new study reported in Gut an international gastroenterology journal, concluded that the rate of colon cancer was reduced by 64% in the offspring of pregnant and breast-feeding rats fed folic acid supplements. Pregnant and lactating rats were placed on a control or supplemental diet (2.5 times the folic acid of the controls) prior to mating, and during pregnancy and lactation. At weaning, males from each maternal diet group were randomly assigned to a control or supplemental diet group (55 in each of the 4 groups) for 31 weeks Colorectal cancer was induced by azoxymethane at 5 weeks of age.
Results showed that maternal but not post weaning supplementation of folic acid significantly reduced the risk of colorectal adenocarcinoma by 64% in the offspring. The offspring from mothers in the control group who were subsequently fed supplemental folic acid had a higher tumor rate than the others. Thus, maternal supplementatioj of folic acid reduced the risk of tumors whereas post weaning supplementation did not.

Calcium and Colorectal Cancer

Friday, September 4th, 2009

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A new study by the National Institutes of Health and AARP found that people who consume more calcium and dairy foods have a lower risk of colon cancer. Diet and other information was collected on over 50,000 people between the ages of 50 and 71. After 7 years the risk of colon cancer was about 20% lower in men who consumed the most calciuim from food and supplements (about 1,500 mg. daily) than in men who consumed the least (about 500mg daily).

The risk in women was about 30% lower for women who consumed the most calcium (about 1,900 mg daily) that those who consumed the least (about 500 mg daily). Colorectal cancer was also lower in men and women who ate the most daily foods. However, contract to earlier stuidies dairy was not linked to a higher risk of ovarian cancer and calcium was not linked to a higher risk of prostate cancer.

It is best to try to ingest 1,000 mg daily of calcium if you are under 50 and 1,200 mg daily if you are older. If you assume there is 300 mg in each serving of milk, cheese, yogurt, or calcium-fortified orange juice take a supplement to get any additional calcium needed. In light of the earlier studies of calcium and prostate cancer (not found here) men may want to limit intake of calcium to 1,200 mg daily. Additional information can be found in the Archives of Internal Medicine, 169:391, 2009.

An Aspirin a Day and Weightlifting May Keep the Cancer Away

Friday, August 21st, 2009

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A study reported this month concluded that a daily dose of aspirin decreases the risk of death from colon cancer. Although it has been know that aspirin reduces the risk of developing colon cancer this study that needs to be replicated found that the risk of death in those with colon cancer is reduced by daily aspirin. The study reported in the Journal of the American Medical Assn reviewed 1,279 cases of men and women with colon cancer without metastasis and at different stages from 1980 to 2008. One of the two groups took a regular dose of aspirin (325mg) at least twice a week for a total dose of 650 mg or more for a week. Those with colon cancer and on the aspirin dose were 29% less likely to die of colorectal cancer and 21% less likely to die overall. More information is available at:
http://jama.ama-assn.org/cgi/content/abstract/320/6/649

A second study looked at weight lifting and breast cancer. In the past women treated for breast cancer were warned not to lift heavy items such as babies and groceries to avoid chronic arm swelling (lymphedema). Results of a new study from the University of Pennsylvania reverses this advice. In the study, women who lifted weights twice a week for a year after breast cancer had fewer debilitating symptoms and flare-ups and some of the 70 women were able to completely control the fluid buildup. This study was the the largest and most rigorous to show the benefits without risks of slow, progressive, strength training for women with breast-cancer related lymphedema. More information is available in: Schmitz, K, Ahmed, R, Troxel, A. et al (2009)
Weight Lifting in Women with Breast-Cancer-Related Lymphedema, NEJM, Vol 361, No 7, August 13, 664-672.