Posts Tagged ‘ER-. ER+’

Do Fruit and Vegetables Influence the Risk of ER Breast Cancer?

Friday, February 1st, 2013

logo1267406_mdA new study published in the Journal of the National Cancer Institute concluded that there is no association between fruit and vegetable intake and risk of overall breast cancer, but vegetable intake is associated with a lower risk of estrogen receptor-negative (ER-) breast cancer. Data were analyzed from 20 cohort studies of women who were followed for a maximum of 11 to 20 years and who consumed low compared to high intakes of fruit and vegetables and had risk of developing breast cancer in each study. Data on study specific estimates were combined from all studies to generate a summary estimate for all studies combines. Results showed that total fruit and vegetable intake was statistically significantly¬† linked to a lower risk of ER- breast cancer, but not with risk of overall breast cancer or risk of ER+ breast cancer. Results showed lower risks were mostly associated with higher vegetable consumption. The researchers said “These findings support the value of examining etiologic factors in relation to breast cancer characterized by hormone receptor status in large pooled analyses because modest associations were less common breast cancer subtypes may have been missed in smaller studies.”