Posts Tagged ‘genetic risk’

Can Men with a High Genetic Chance of Bowel Cancer lower their Risk with a Healthy Lifestyle?

Wednesday, October 5th, 2016

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Recent research published in the journal Genetics in Medicine concluded that men with a high genetic risk of developing bowel cancer over the next 25 years could have a lower of developing the disease if they have a healthy lifestyle. They continue that men of 50 who have a high risk of developing bowel cancer have a 29 per cent risk of developing the disease within 25 years and by living healthy the risk could drop as low as 13 per cent.

In the study genetic and lifestyle risk factors were combined to help find men at the highest risk of developing bowel cancer.  Mathematical models of 37 different factors that could put people at risk of cancer were used to calculate how likely it was for a man to be diagnosed with bowel cancer over the following 25 years. Factors included inherited genetic faults increasing the risk of bowel cancer, and lifestyle factors affecting that risk such as consumption of alcohol, red meat, and fruit and vegetables, body mass index, smoking habits, physical activity, aspirin use, and inflammatory bowel disease. Based upon their findings they estimated 610 cases of bowel cancer could be prevented over the following 25 years if 10,000 men in the highest risk category had the healthiest lifestyle.  For men in the lowest risk group, 70 cases of bowel cancer could be prevented.

Researchers concluded “Bowel cancer is one of the biggest cancer killers and the number of cases is going up in the Western world. We have made big strides in our understanding of the genetic and lifestyle factors  that can contribute to the development of bowel cancer, and that gives us an opportunity to begin assessing people for their future risk. If we can identify people who are at a strongly increased risk, through genetic and lifestyle factors, we can begin to give them targeted health messages, aimed at helping them make choices that could prevent the disease.”