Posts Tagged ‘high levels’

Can a High Level of Vitamin B12 Indicate a Risk of Cancer?

Wednesday, November 27th, 2013

logo1267406_mdA new study published in the Journal of the National Cancer Institute concluded that vitamin B12 is essential for maintaining healthy bodily functions but higher than normal levels of 200 to 600 pmol/L may indicate the person is at -risk of developing certain cancers. Previous studies have also seen this association.,

To evaluate this association, the researchers reviewed 333,667 patients from the Medical registry in Denmark  between 1998 and 2010./ These patients did not have cancer but had been referred for vitamin B12 testing. Patients with a diagnoses of cancer before the testing and those receiving Vitamin B12 therapy were excluded. They found that the risk of cancer increased with higher vitamin B 12 levels especially for those with levels above 800pmol/L. After 5 years of follow-up the risk of hematological and alcohol and smoking-related cancers remained high for those with levels above 800pmol/L/ Researchers concluded “high plasma vitamin B12 levels increased the risk of subsequently diagnosed cancer. mostly within the first year of follow up. ” They also believe that high vitamin B12 levels in food do not usually increase vitamin B12 levels significantly and instead, high vitamin B12 levels may result from some unknown malignant process.