Posts Tagged ‘HPV’

Curcumin As A Potential Therapy for Cancer Caused by HPV

Wednesday, April 29th, 2015

HPV and Curcumin as Potential Therapy for Cancer

HPV: A new study published in EurekAlert concluded that Curcumin, an antioxidant, found in the curry spice Tumeric, will slow or limit the activity of the Human Papilloma Virus (HPV), that causes oral and cervical cancer.  Authors say “Tumeric has established antiviral and anti-cancer properties and according to our new findings, we could say that its good for oral health too.”  The researchers first noted the effect of curcumin on HPV and cervical cancer cells in 2005 and because oral cancer rates are rising  they tested the same hypothesis on oral cancer. They found that Curcumin turns down the expression of HPV in infected oral cancer cells by down regulating the level of cellular transcription factors   AP-1 and NF-KB and this suggests a new potential new role for Curcumin in cancer control.

Can a Common Virus be Linked to Lung Cancer?

Friday, April 19th, 2013

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Researchers p[resenting at the American Association of Cancer Research (AACR) Annual Meeting this month concluded that a common virus known to cause cervical and head and neck cancers may also cause some cases of lung cancer. After examining tissue samples from lung cancer patients researchers found that  nearly 6% seemed to have been driven by a strain of human papilloma virus (HPV)  Researchers examined 36 tissue samples from people diagnosed with non-small cell lung cancer who had never smoked.  Non-smokers were chosen because because smoking is a major cause of lung cancer but the causes in non-smokers is less well understood. They found that 4 of the 36 samples had signs of infection from two strains of HPV that were known to cause cancer–16 and 18. When looking more closely at the two samples infected by HPV they found that the virus had integrated into the tumor’s DNA–suggesting more strongly that the infection caused the tumor. Further research is needed to confirm the results seen in this sample.

Human Papilloma Virus Triggers Mouth and Cervical Cancer

Wednesday, December 29th, 2010

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A new study reported in the British Journal of Cancer concluded that ” a protein in cells called Cdc42, which is already known to be implicated in a number of cancers as well as in tumor spread, is inappropriately activated by the human papilloma virus.” Thus, the researchers discovered a new way for the HPV to trigger cancer that may lead to new treatments for cervical and mouth cancers. This discovery of a mechanism adds to the knowledge that HPV increases the risk of developing cervical and mouth cancers and accounts for about 70% of all cervical cancer cases. Knowing how the virus caused the diseases may help in identifying prevention and treatment of HPV related cancers.
More information can be found at:

http://www.sciencedaily.com/releases/2010/12/101214085732.htm