Posts Tagged ‘inflammation’

Are Exercise and Caffeine Protective Against Sun Exposure Skin Cancer?

Friday, April 13th, 2012

A new study reported at the American Association of Cancer Research last week concluded that the combined effects of exercise and caffeine consumption may prevent skin cancer and also prevent inflammation related to other obesity-linked diseases. These results were found in a mouse model study but the researcher believes  “we may extrapolate these findings to humans and anticipates that we we would benefit from these combination treatments as well.”

Using mice at high risk of developing skin cancer researchers evaluated the effects of caffeine and exercise and found that mice that took a dose of caffeine and exercised on a running wheel had 62% fewer skin tumors. In addition, the volume of tumors also decreased by 85% compared with mice that did not exercise or take caffeine.  Positive effects were also found for either intervention alone but to a lesser degree.  Findings were a 27% reduction in skin tumors for caffeine only mice and a 61% reduction in tumor size. They found the tumor activity was reduced by 35% and the tumor volume by 70% in exercise-only mice. They also found that combined exercise and caffeine reduced weight and inflammation when mice were fed a high-fat diet of omega-6 fatty acid-rich  foods for two weeks.  These results were again higher when the two interventions were combined than with either one alone.

How Does Mate Tea act on Colon Cancer Cells?

Friday, February 3rd, 2012

An invitro study published in Molecular Nutrition & Food Research concluded that “caffeine derivatives in mate tea not only induced death in human colon cancer cells, they also reduced important markers of inflammation.” Inflammation can trigger the progression of cancer. In the study, researchers isolated, purified, and then treated human colon cancer cells with caffeoylquinic acid (CQA) from mate tea and as they increased the CQA concentration cancer cells died as a result of apoptosis. In other words, “cancer cells self-destruct because its DNA has been damaged.” The researchers identified the mechanism that led to cell death and have completed a follow up study in which they compare the development of colon cancer in rats that drank mate tea as their only source of water with a control group that drank only water. These results will be published soon.
The researcher concluded “We believe there’s ample evidence to support drinking mate tea for its bioactive benefits especially if you have reason to be concerned about colon cancer. Mate tea bags are available in health food stores and are increasingly available in large supermarkets.”

Inflammation and Cancer Growth and Metastasis

Wednesday, January 19th, 2011

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In a new study being published in the net edition of Cancer Cell researchers demonstrated that HRG (histidine-rich-glycoprotein), a protein that naturally occurs in the body will inhibit the growth and spread of cancer cells by activating specific immune cells. However, this process is dependent upon inflammatory cells which are caused by most cancers and may either stimulate the growth of tumors or inhibit them. This cancer caused inflammation consisting of tumor associated macrophages (TAM’s) that are either M2 macrophages that support cancer cell growth and moderate the body’s immune defense, or M1 macrophages that inhibit tumor growth by activating immune cells that are toxic to the tumors.

The researchers say “”HRG can transform inflammatory cells in the tumor from M2 macrophages, which promote tumor growth, to M1 macrophages, which inhibit tumor growth” and “M1 macrophages also inhibit the spread of tumor cells….”.

Studying 3 different types of tumors in mice they found the tumors producing HRG grew more slowly and did not spread. In the process the HRG caused M2 macrophages to transform into M1 macrophages. Further research is planned.

Additional information can be found at:
http://www.eurekalert.org/pub_releases/2011-01/uu-sci010511.php

Breast Inflammation Related to Cancer Growth

Friday, December 24th, 2010

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A study reported in the December 15 issue of Cancer Research concluded that an inflammatory process in the breast promotes the growth of stem cells responsible for the development of tumors. They further stated that “inactivating the NFKB inflammatory pathway in the breast epithelium blocks the onset and progression of the breast cancer in living animals.” Although there are side effects to suppressing the whole body’s inflammatory processes, the study showed a rationale for selectively targeting the breast only in anti-inflammatory therapy.

After 12 years of research the researchers created a mouse in which the inflammatory system in the adults breast could be regulated. These mice were programmed to develop cancer but if they selectively blocked inflammation in the breast, the tumors would not develop. They also found that this inactivation reduced the number of cancer stem cells in the breast.

Doctors of Medicine, Oriental Medicine, and Naturopathy Discussed Natural Ways to Deal with Seasonal Allergies

Sunday, September 5th, 2010

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Yesterday on the Holistic Health Show Dr Carl O Helvie interviewed Dr Murray Grossan, M.D., Dr Steven Morrissey, O.M.D., and Dr Bianca Garilli, N.D. about natural ways to deal with seasonal allergies. Dr Grossan is board certified by the American Board of Otolarngology and Head and Neck Surgery and is currently at Cedars-Sinai Medical Towers in Los Angeles. More information is available on an earlier blog on this website or at www.ent-consult.com

Dr Steven Morrissey has more than 25 years experience in oriental and herbal medicine and has two joint companies with others in China to undertake research on safety, efficacy and quality of botanical medicine. More information is available on an earlier blog and on www.plantiva.com

Dr Bianca Garilli, a naturopathic physician, practices in Orange County, California. More information was presented earlier on this site and can also be found at www.ocnmp.com and www.allergyeliminationdiet.com

Enjoy the interview below.

Natural Solutions for Seasonal Allergies Discussed by Dr Dobri Kiprov and Dr Ann Lovick on the Holistic Health Show

Sunday, July 25th, 2010

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Dr Carl O Helvie, host, interviewed Dr Dobri Kiprov and Dr Ann Lovick on the Holistic Health Show yesterday. Both talked about natural solutions for seasonal allergies.

Dr Kiprov a physician and pioneer in the field of immunology is chief of immunology at California Pacific Medical Center in San Francisco. He is world renown for his work. More information is available on an earlier blog and at: www.lifestyleinmotion.com and www.dobrikiprov.com

Dr Lovick is a naturopathic physician who is on the staff of Integrative Health Care in Scottsdale, Arizona and has been a lifelong sufferer of allergies. More information is available on an earlier blog and also at: Http://integrativehealthcare.com/drlovick.htm

The interview follows:

Seasonal Allergies Discussed by Dr Fred Pescatore and Dr Lauren Feder

Sunday, July 11th, 2010

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Yesterday, Dr Carl O Helvie, Host, the Holistic Health Show, interviewed Dr Fred Pescatore and Dr Lauren Feder about seasonal allergies. Dr Pescatore is an internationally known physician who is recognized as a health, nutrition, and weight loss expert, has hosted his own radio show and appeared on major radio and television programs, authored several books including the best seller Thin for Good. and and the Allergy and Asthma Cure, and Founded the Dr Pescatore’s Health for Good products. More information on Dr Pescatore and his activities was identified on an earlier blog and can be found at: www.Hamptomsdiet.com

Dr Lauren Feder, a nationally known physician is in private group practice in Los Angeles, has appeared on national programs including Oprah and Friends with Dr Mehmet Oz, and is author of Natural Baby and Child Care and The Parents Concise Guide to Childhood Vaccines. More information appeared on an earlier blog and can also be found at www.drfeder.com

The Mechanisms of Asbestos Causing Lung Cancer

Friday, July 9th, 2010

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A study published in the Proceedings of the National Academy of Science explained why asbestos causes cancer. The researchers looked at the paradox of how asbestos fibers that kill cells can cause cancer when dead cells should not grow to form tumors. Findings show that when asbestos kills cells, it induces a process called ‘programmed cell necrosis” releasing a molecule called high-mobility group box 1 protein (HMGB1). This starts an inflammatory process causing the release of mutagens and factors that promote tumor growth.
The researchers found that patients exposed to asbestos had elevated levels of HMGB1 in their blood. Thus, it may be possible to identify those with asbestos by simple HMGB1 blood tests and targeting these individuals for prevention and treatment.
The researchers are interesting in determining whether interfering with the inflammatory reaction caused by asbestos and HMGB1 can decrease the cancer incidence of cohorts exposed to asbestos. They also wonder if taking an aspirin or similar drug that stops inflammation will prevent mesothelioma. More research is planned to test this hypothesis.

Natural Ways to Deal with Back Pain

Sunday, May 16th, 2010

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On the Holistic Health Show yesterday Dr Carl O Helvie interviewed Frank Titus (left) and Mitchell Yass (right) on natural ways to treat back pain.
Frank has a B.S. degree in Exercise {Physiology and is founder of Health Through Motion and uses Titus Motion Therapy with high profile entertainment and sports individuals. More information was presented earlier on this blog or can be found at www.titusmotiontherapy.com

Mitchell Yass is a physical therapist and is known as the “Miracle Man” on Long Island for his work with pain. His goal is to help others avoid surgery and drugs in the resolution of back pain. More information is available on an earlier blog and on www.mitchellyass.com

Both practitioners say they have achieved over a 90% success rate in resolving pain with natural methods.

Enjoy the interview below.

Avoid Knee Replacement and Harsh Treatments for Arthritis

Sunday, January 24th, 2010

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Last night Dr Carl O Helvie, Host, Holistic Health Show interviewed Dr Ross Hauser (left) and Dr Thom Lobe (right).

Dr Hauser talked about prolotherapy a medical procedure of injecting natural substances into a site such as the knee to regenerate cartilage. He has been performing this procedure sucessfully for 12 years and studied with the physician who invented the procedure., He has also written books on the procedure. More of his biography was presented on this site earlier and can be found at http://www.caringmedical.com

My second guest was Dr Thom Lobe who is the founder and medical director of Beneveda Medical Group in Beverly Hills, California. He has been first many times such as successful separation of siamese twins, establishment of first pediatric surgery training program in the south, first textbook on pediatric surgery, first medical journal devoted to advanced surgical treatments in children and others. He is also a long time host and moderator of a medical talk show on GHS television in Germantown, Tennessee called “Whats Up Doc?”. Others aspects of his biography were identified earlier on this site and can be found at www.beneveda.com Dr Lobe talks about natural ways to deal with arthritis.

The interview follows. I hope you enjoy it.