Posts Tagged ‘longevity’

Longevity/Fasting/Stem Cells and Dr Valter Longo, the Guru of Longevity

Sunday, July 15th, 2018

Professor Valter Longo is internationally recognized as a leader in the field of ageing studies and related diseases. His discoveries include some of the major genetic pathways that regulate aging and life-threatening diseases and the identification of a genetic mutation that protects men from several common diseases.

He is a Professor of Gerontology and Biological Science and Director of the Longevity Institution at the School of Gerontology at the University of Southern California in Los Angeles, one of the leading centers devoted to teaching and research on ageing. He is also director of the Oncology Laboratory and longevity at the Institute of Molecular Oncology IFOM in Milan.

Professor Longo received the Nathan Shock Lecture Award from the National Institute on Ageing (NIA/NIH) in 2010 and in 2013 the Vincent Cristofalo ‘Rising Star’ Award for Research on Ageing, and the 2016 Glenn Award for research in the Biology of Aging.

In 2015, after a number of his papers were among the most widely cited in the biomedical field, Time magazine called him a ‘guru of longevity’.

Doctor Longo received a PhD from North Texas in 1992, and another one from UCLA in 1997 and completed post doctoral training in 2000. He has carried out research in the areas of fasting and longevity, cell biology and genetics, the regulation of aging and multiple  stress resistance systems in yeast and mammals, cancer, diabetes and Alzheimer’s.  He has over 70 peer reviewed articles, 4 books/chapters, multiple research grants, active grant reviewer, and student research advisor. He is author of the best seller The Longevity Diet: Discover the New Science Behind Stem Cell Activation and Regeneration to Slow Aging, Fight Disease, and Optimize Weight

More information is available at:                                                                              http://gero.usc.edu/cv2013/CV-LongoV2013.pdf

www.CreateCures.org

Enjoy the Interview Below:

 

Drinking Coffee may Increase Life Span.

Wednesday, November 29th, 2017

 

A review of over 200 studies published in the British Medical Journal suggest that frinking three or four cups of coffee daily is linked to a lower risk of early death  and getting heart disease  than not drinking coffee. The researcher said drinking coffee “is more likely to to benefit health than harm it” for a range of health outcomes such as cancer, diabetes, kiver dusease and dementia. Exceptioms are women who are pregnant and those who suffer fractures.

No firm conclusions can be drawn because the majority of studies were observational but back up other recent studies. Thus, they say “with the exception of pregnancy and women at risk of fractures “coffee drinking appears safew within usual patterns of consuymption” and could be tested further inrandomized studies.

In the study the largest reduction in death was related to drinking 3 cups a day compared with non-coffee drinkers. Drinking moire than 3 cups daily were not associatioted with harm but were not as beneficial. Beneficial effects related to a lower risk of several cancers including prostate, endometrial, skin, and liver, as well as tyoe 2 diabete, gall stones, and gout. The greatest benefit weas seen for liver disease such as cirrhosis. Additional benefits were seen for Parkinson disease, depression, and Altzheimers disease. Researchers recommended against starting drinking coffee for health benefits until the evidence of an association is stronger.

Can a Feast and Famine Diet Extend Life?

Wednesday, March 4th, 2015

Fasting on feast and famine diet

Is increased longevity a result of fasting with a feast and famine type diet? One of the guests this week discussed weight loss at Structure House. This research follows.

A new study reported in the journal Rejuvenation Research concluded that intermittent fasting caused a slight increase to SIRT 3, a well known gene that promotes longevity and is involved in protective cell responses. The researchers say that fasting in mice has been shown to extend lifespan and improve related diseases but daily fasting would be hard to maintain. This lead to the idea of intermittent fasting. In the study researchers measured changes in weight, blood pressure, heart rate, glucose levels, cholesterol, markers of inflammation and genes involved in protective cell responses of participants over a ten week period. On fasting days, participants ate food such as roast beef and gravy, mashed potatoes, Oreo cookies and orange sherbet but they ate only one meal. On feasting days, they ate bagels with cream cheese, oatmeal sweetened with honey and raisins, turkey sandwiches, apple-sauce, spaghetti with chicken, yogurt and soda–and lemon pound cake, Snicker bars, and vanilla ice cream.  Participants like the fasting days better and had trouble getting enough calories on the feasting days.

Twenty four participants were involved in the double-blind, randomized clinical trial. During a three week period subjects alternated one day of eating 25% of their daily calorie intake with one day of eating 175% of their daily caloric intake. For the average male, this would be 650 calories on fasting days and 4,550 calories on feasting days. To test antioxidant supplements, subjects received the diet but also included vitamin C and E. At the end of 3 weeks the health parameters identified above were tested. Researchers found the beneficial sirtuin proteins such as SIRT 3 and another, SIRT 1, increased as a result of the diet. When antioxidants were supplemented on top of the diet, however, some increases disappeared consistent with previous research indicating that flooding the system with antioxidant supplements may counteract the benefits of exercise and fasting.

Can a Sense of Meaning and Purpose Extend Life and Overcome Illness?

Friday, November 14th, 2014

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A new study published in Lancet of 9,050 people with an average age of 65 found that the people with the greatest well-being were 30% less likely to die during the eight and a half year follow-up period than those with less well being. Questionnaires were used to measure a type of wellbeing called “eudemonic wellbeing” which relates to a sense of control, feeling that what you do is worthwhile, and a sense of purpose. People were placed into one of four categories of highest to lowest wellbeing based upon their answers. Results were adjusted for age, sex, socio-economic status, physical health, depression, smoking, physical activity, and alcohol intake to rule out as many of the factors that might influence wellbeing and life expectancy.

Over the eight and a half year period of follow-up 9% of the people in the highest wellbeing group had dies whereas 29% died in the lowest category. After all influencing factors were considered the group with the highest wellbeing were 30% less likely to die over the study period living on average two years longer than those in the lowest wellbeing.

Can a Sense of Purpose Increase your Life Span?

Friday, May 23rd, 2014

logo1267406_mdA new study published in Psychological Science concluded if you feel you have a sense of purpose in life it helps you to live longer, no matter what age you are. The researchers said “Our findings point to the fact that finding a direction for life, and setting overarching goals for what you want to achieve can help you actually live longer, regardless of when you find your purpose.”

Although previous studies have suggested that finding a purpose in life lowers the risk of death above and beyond other factors known to predict longevity, almost no previous studies evaluated whether or not the benefits of purpose vary over time, such as across different developmental periods or after important life transitions.  This study looked at that question.

Data from over 6,000 individuals focusing on their purpose in life were evaluated using questions such as “Some people wander aimlessly through life, but I am not one of them.” They also looked at other psychosocial variables to gauge positive relations with others and their experience with positive and negative emotions.

Five hundred sixty nine of the 6,000 subjects died over the 14 year follow up period (about 9% of the sample). This group had reported lower purpose in life and lower positive relations than did the survivors. Great purpose in life consistently predicted lower mortality risk across the lifespan and showed the same benefits for young, middle aged, and older subjects across the follow up period. Interesting, purpose had similar benefits for adults regardless of retirement status, a known mortality risk  factor. The researchers reported that these longevity benefits of purpose in life were consistent even after other indicators of psychological well being such as positive relations and positive emotions were considered. Researchers said “These findings suggest that there’s something unique about finding  a purpose that seems to be leading to greater longevity.” Researchers current research is focusing on whetehr or not having a purpose might lead to a healthier lifestyle that influences longevity.