Posts Tagged ‘obesity’

Can Lifestyle Factors Reduce the Risk of Esophageal Cancer?

Friday, April 12th, 2013

logo1267406_mdRecent news from the Seattle Barrett’s Esophagus Program  at the Fred Hutchinson Cancer Research Center in collaboration with Brigham & Women’s College and the University of California in San Francisco have shown that a systematic approach to early  cancer detection can boost five-year survival rates from about 15 percent to more than 80 percent. They  have also shown that modifiable lifestyle factors-from reducing obesity to quitting smoking–may also prevent progression of Barrett’s esophagus to esophageal cancer. Some of the ways to prevent this condition from progressing to esophageal cancer were identified and follow.

Earlier research in 2007 reported that people with the more aggressive form of Barrett’s may benefit gfrom preventive therapy with aspirin or other non steroidal anti-inflammatory drugs. Following Barrett’s patients over time they identified a cluster of 4 known cancer bio markers  in this group that increased their risk of developing esophageal cancer. They found that subjects with 3 or more of these bio markers who also used aspirin or other no0nsteroidal anti inflammatory drugs (NSAID’s)  had a 30 % chance of developing esophageal cancer after 10 years whereas those who did not use the aspirin had a 79% change of developing cancer with a decade. They believe aspirin and other non-steroidal inflammatory drugs may fight cancer by reducing chronic  inflammation. However, because this was a long term observational study and not a clinical trial they cannot recommend aspirin for people with Barrett’s and also advise that anyone wh uses them do so under medical direction because of the side effects such as g.i. bleeding.

Another study looked at Barrett’s and statin drugs for lowering cholesterol and found that various combinations of statin and/or NSAID’s used by patients with Barrett’s and and high grade dysplasia had a reduced risk of esophageal cancer when compared with those who did not use these drugs.

This year they lo0ked at lifestyle and esophageal cancer and found that heavy smokers with Barrett’s were more than twice as likely to develop esophageal cancer than non-smokers with Barrett’s. They also found that obesity especially belly fat, was more strongly associated with the progression of Barrett’s to esophageal cancer.

They also offered suggestions for managing the symptoms of chronic acid reflux that is a risk factor for Barrett’s. These included smoking cessation, keeping weight down, getting regular exercise, eating a diet rich in fruit and vegetables, refrain from eating four hours before retiring, elevate the head of your bed if you have heart burn, and take antacids for occasional heartburn and see you doctor if you have frequent heartburn or if over the counter medications do not help.

Does Childhood Obesity Increase the Risk of Adult Cancer?

Friday, August 3rd, 2012

New research published in the journal of Cancer Epidemiology. Biomarkers and Prevention and Obesity concluded that obesity in adolescents has a direct link to the incidence of urothelial (bladder and urinary tract) and colorectal cancers in adulthood when obesity is defined as a Body Mass Index (BMI) in the 85th percentile and above. This group of adolescent has a 1.42% greater chance (50% higher risk) of developing urothelial or colorectal cancer in adulthood than those beneath it.

Researchers conducted a longitudinal study of 1.1 million males in the Israel Defense Force using health information collected by the army for a follow-up period of 18 years. When controlled for factors such as year of birth and education, the researchers discovered a clear link between childhood BMI and those diagnosed with urothelial or colorectal cancer later in life. Although at this time the researchers have only found a link between childhood  BMI and these types of cancer later in life they believe further research may find a wider range of cancers including pancreatic cancer which they are currently researching. Further research will evaluate whether or not obesity is a direct risk factor for cancer or a confounding factor for a genetic variation and whether or not a successful weight loss program can reduce a child’s risk of developing urothelial and colorectal cancer in adulthood.

Use Alternatives to Reduce Type 2 Diabetes Risks

Wednesday, July 25th, 2012

John LaGrace, National Awareness Director, DrugWatch.com was kind enough to provide the following guest blog written by his staff on alternatives to reduce Type 2 diabetes. I hope you enjoy it.

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Doctor Mark Hyman, author of the “The Blood Sugar Solution,” described diabetes as a foodborne illness. While the exact cause of diabetes isn’t well understood there is a recognizable link between fat buildup from unhealthy foods and the onset of the disease. The American Diabetes Association says that about 50 percent of men and 70 percent of women are obese when they are diagnosed.

This link between obesity and type 2 diabetes opens up the door to exciting possibilities for naturally fighting symptoms. Even if a person isn’t obese, adjusting their amount of exercise and beginning a healthy diet can drastically reduce symptoms. Doctors say that patients only need to lose 5 to 10 percent of their body weight to see an improvement.

The Look AHEAD study showed that people with type 2 diabetes benefit the most from natural treatments when they seek out the help of professionals like dieticians and personal trainers. Doctors should also be consulted before attempting to modify your exercise or diet to treat diabetes. With a combination of expert guidance you can develop a well-rounded and effective treatment plan. In the Look AHEAD study people with type 2 diabetes who received professional guidance were able to keep significant weight off consistently, while those who didn’t saw fewer results.

Medical studies show a combination of diet and exercise are the most effective natural treatments to reduce diabetes symptoms. Exercise helps sensitize the body to insulin, which lowers blood sugar. It also reduces harmful cholesterol, which reduces the risk of congestive heart failure.

Patients should begin their lifestyle changes progressively. After talking to a Doctor they can begin to make conservative changes in diet and exercise, and then see how their body reacts. By pacing themselves people avoid potentially over stressing their body, or lowering their blood sugar too rapidly. As the body adjusts to a new health routine people can gradually increase the aggressiveness of their natural treatment.

The health risks of congestive heart failure and stroke are serious side effects associated with diabetes medications are serious and should be addressed. In fact, the FDA has issued a black-box warning on type 2 diabetes medication, Actos, because of its link with congestive heart failure. This has resulted in many users filing an Actos lawsuit against the manufacturer.

Having type 2 diabetes may make changing diet and regular exercise more difficult, but with enough discipline people may actually be able to beat the disease. One British study showed that with dramatic lifestyle intervention type 2 diabetes can actually be reversed in some patients.

The American Diabetes Association says that people can have an impact on their symptoms by starting to exercise 30 minutes a day for five days a week. Exercise doesn’t have to be strenuous either. Working around the house or walking is sufficient to improve heart health and reduce the risk of diabetes related symptoms. Be sure to warm up before jumping into a fitness routine, and always consult your doctor about beginning natural treatment.

William Richards researches and writes about prescription drugs and medical devices for Drugwatch.com.

Sources:

Fox Business. (February 28, 2012). Fighting the Nation’s Diabetes Problem. Fox News. Retrieved from http://video.foxbusiness.com/v/1477767213001/fighting-the-nations-diabetes-problem/

Wadden T, West DS, Delahanty L, Jakicic J, Rejeski J, Williamson D, Berkowitz R, Kelley D, Tomchee C, Hill J, Kumanyika S. (May 2006). The Look AHEAD study: a description of the lifestyle intervention and the evidence supporting it. PubMed. Retrieved from

http://www.ncbi.nlm.nih.gov/pubmed/16855180

BBC. (June 23, 2011). Type 2 Diabetes in newly diagnosed ‘can be reversed.’ Retrieved from http://www.bbc.co.uk/news/health-13887909

Nutrition and Weight Loss Interviews with Dr Larry McCleary, Dr Catherine Jen, and Alyson Mead now available.

Sunday, April 1st, 2012

Guests on the show yesterday were Dr Larry McCleary  (far left), Dr Catherine Jen (middle) and Alyson mead (right).

Dr McCleary is retired Acting Chief of Neurosurgery at  Denver Children’s Hospital and author of Feed Your Brain: Lose Your Belly and The Brain Trust Program: A Scientifically Based Three Part Plan to Improve Memory, Elevate Mood, Enhance Attention, Alleviate Migraine and Menopausal Symptoms and Boost Mental Energy. More information was presented earlier on this blog and can also be found at: http:www.drmccleary.com

Dr Catherine Jen is Professor and Chair of the Department of Nutrition and Food Science at Wayne State University and currently has a grant for over 5 million dollars to study Interventions Procedures for Adherence to Weight Loss Recommendations in Black Adolescents and has 104 publications, and 31 patents. More information was presented earlier on this blog.

Alyson Mead has been psychic since childhood and is the best selling author of Wake Up to Your Stories and Wake Up to Your Weight Loss. She is a story teller and uses meditation in her practice. More information was presented earlier on this blog and can also be found at:  http://www.sassypsychic.com

Enjoy the Interview Below:

Combination of Diet and Lifestyle Influence Risk of Diabetes in Women

Wednesday, September 21st, 2011

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A new study published in the New England J. Medicine looked at the combined effects of diet and lifestyle in relation to risk of type 2 diabetes and concluded that the “majority of cases of type 2 diabetes could be prevented by the adoption of a healthier lifestyle.”

Between 1980 and 1996, 84,941 female nurses were followed who were free of diagnosed cardiovascular disease, diabetes, and cancer. Information was updated periodically on their diet and lifestyle. A low risk-group was defined with the following criteria: a body-mass index of less than 25, a diet high in cereal fiber and polyunsaturated fats and low in trans fats and glycemic load, engagement in moderate to vigorous physical activity for at least half an hour daily, no current smoking, and the consumption on average of at least half a drink of an alcoholic beverage daily.

During the study period 3300 new cases of type 2 diabetes were documented and researchers found that overweight or obesity was the single most important predictor of diabetes. However, after adjustment for the body-mass index, a lack of exercise, a poor diet, current smoking, and abstinence from alcohol use were all significantly associated with an increase risk of diabetes

Risk of Diabetes Higher Among Those With Lifetime Excessive Weight

Wednesday, September 14th, 2011

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A new study published in the Archives of Pediatric Adolescent Medicine concluded that number of years spent with excess weight and how much weight plays a role in the risk for developing Type 2 diabetes. They pointed out a similarity of the risk of diabetes for those with long term obesity to lung cancer for those with long term heavy smoking. The researchers found that a BMI of 25 or over-the combination of weight and height- sustained for a number of years is a better indicator of the risk for type 2 diabetes than the single measure of excessive weight. .
In the study, researchers studied about 8,000 adolescents and young adults and concluded that diabetes may become more prevalent that previously predicted because of the number of obese children and adolescents in the United States. They found that Hispanics and blacks had a higher rate for diabetes compared to whites for the same amount of excess weight over time.

Risk of Triple-Negative Breast Cancer May Be Increased by Obesity

Friday, March 18th, 2011

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Research published in Cancer Epidemiology: Biomarkers & Prevention confirmed that obesity and lack of physical activity increase the risk of triple-negative breast cancer among women. Triple-negative breast cancer accounts for about 10 to 20 percent of all breast cancers, has a poor prognosis. and is a subtype of breast cancer characterized by a lack of estrogen, progesterone and HER2 expression.

The researchers analyzed data from over 155,700 women enrolled in the Women’s Health Initiative. Assessing levels of baseline body mass index (BMI) and recreational activities among 307 women with triple-negative breast cancer and 2,610 women with estrogen receptor-positive breast cancer they found that women with the highest BMI had a 35% increase risk of triple-negative breast cancer and a 39% increased risk of estrogen receptor-positive breast cancer. While evaluating the role of exercise they found that those who reported
high rates of physical activity had a 23 percent decrease risk of triple-negative breast cancer and a 15% decrease risk of estrogen receptor-positive breast cancer.

More information is available at:

http://www.sciencedaily.com/releases/2011/03/110301142011.htm

Lower Risk of Cancer by Cutting Fat and Calories

Friday, July 30th, 2010

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Research presented at the 2010 Institute od Food Technologists (IFT) Annual Meeting & Food Expo concluded that as many as 1 out of 3 cancer deaths in humans and dogs could be prevented by cutting calories and reducing Omega-6 fatty acids. They stated that too much Omega-6 from fats found in corn-oil, vegetable oil, and grain fed red meat can lead to inflammation that in turn creates an environment conducive to cancer. In addition, to reducing Omega-6 fats they suggested reducing calories especially sugar that causes obesity and also feeds and encourages the growth of cancer cells. Obesity has been shown to limit the production of adiponectin, a hormone that inhibits the growth of cancer cells.

Lose Weight to Reduce Cancer Risk?

Friday, February 12th, 2010

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Research published in the January 22 issue of Cell confirmed that obesity in mice increased the risk of cancer especially liver cancer. In their study the researchers gave 2 week old mice DEN ( a chemical carcinogen) and divided them into two groups. One group was fed a normal diet that was relatively low in fat and the other group a diet high in fat. The high fat group developed more liver cancer than the normal diet group. To further confirm the link between obesity and liver cancer they gave 2 week old mice DEN that were fed a normal diet but were prone to obesity. This group also developed more liver cancer so the researchers concluded that it was not necessarily the high fat diet but something about the obesity state. They also gave DEN to 3 month old mice on a high fat diet and they also developed more liver cancer. Usually mice on a standard diet given DEN at this age without the extra push of phenobarbitol do not develop liver cancer. But the obese mice developed liver cancer without the extra push of phenobarbitol. The researchers traced the source of the obese cancer producing effect to a rise in inflammatory factors and obese mice lacking these did not show the same rise in liver cancer nor the same distribution of fat in the body. This study suggests that anti-inflammatory drugs used for rheumatoid arthritis and Crohn’s disease may also reduce the risk of cancer for those at high risk of liver cancer because of obesity. .

Dr Jean Franklin Interviewed by Dr Carl O Helvie on Holistic Health Show

Wednesday, May 27th, 2009

jfranklin1 My second guest on Saturday on the Holistic Health Show on BBS Radio (www.bbsradio.com) Station 3 was Dr jean Franklin, a Holistic Nutritionist, in private practice in Williamsville, New York. Jean talked about the value of different types of diets, and the need for supplements. She also talked about changes people should make in their diet to reduce obesity, how she works with obese patients, overall aspects of good nutrition and the pros and cons of drinking distilled water on an ongoing basis. Our interview follows. If interested in a download version of the interview please sign up on another page on this website for a free copy and all future shows to be emailed.