Posts Tagged ‘oral cancer’

Curcumin As A Potential Therapy for Cancer Caused by HPV

Wednesday, April 29th, 2015

HPV and Curcumin as Potential Therapy for Cancer

HPV: A new study published in EurekAlert concluded that Curcumin, an antioxidant, found in the curry spice Tumeric, will slow or limit the activity of the Human Papilloma Virus (HPV), that causes oral and cervical cancer.  Authors say “Tumeric has established antiviral and anti-cancer properties and according to our new findings, we could say that its good for oral health too.”  The researchers first noted the effect of curcumin on HPV and cervical cancer cells in 2005 and because oral cancer rates are rising  they tested the same hypothesis on oral cancer. They found that Curcumin turns down the expression of HPV in infected oral cancer cells by down regulating the level of cellular transcription factors   AP-1 and NF-KB and this suggests a new potential new role for Curcumin in cancer control.

Can Fatty Acids Help Prevent and Treat Cancer?

Wednesday, August 7th, 2013

logo1267406_mdA new research study concluded that Omega-3 fatty acids such as found in salmon and trout selectively inhibit growth and induce cell death in early and late stage oral and skin cancers. The  in  vitro tests showed that these fatty acids induced cell death in malignant and pre-malignant cells at doses that do not affect normal cells and suggests their use in both prevention and treatment of certain skin and oral cancers.

In the lab cell cultures from several different cell lines were grown to which fatty acids were added.The cell lines included both malignant oral and skin SCC’s. along with pre-malignant cells and normal skin and oral cells. The researchersa were suprozed that the cell death of cancer cells t doses that did not effect normal cells was partly due to an over-stimulation of a key growth factor (epidermal growthg factor) that triggers cell death. The researchers said “It could be that those at an increased risk of such cancers-or their recurrence—could benefit from increased omega-3 fatty acids. Moreover, as the skin and oral cancers are often easily accessible, there is the potential to deliver targeted doses locally vuia aerosols or gels. However, further research is needed to define the appropriate therapeutic doses.”