Posts Tagged ‘preCancerous’

Can a Blood Test Detect All Types of Cancer?

Wednesday, August 6th, 2014


New research published online in FASEB Journal, The U.S.Journal of American Societies for Experimental Biology, concluded that a revolutionary blood test that could detect any type off cancer was developed by British scientists. The test6 has been shown to diagnose cancer and pre-cancerous conditions from blood of patients with melanoma, colon cancer and lung cancer with a high degree of accuracy. Researchers assessed white blood cells and measured the damage caused to their DNA when subjected to different intensities of ultraviolet light that is known to damage DNA. They found a clear distinction between the damage to the white blood cells from patients with cancer, with precancerous conditions, and from healthy patients. They also found thatĀ  people with cancer have DNA that is more easily damaged by untraviolet light than other people.

Results were based upon blood samples of 206 people of which 94 were healthy and 114 were patientsĀ  in specialist clinics prior to diagnosis and treatment. Ultra violet damage was observed in the form of pieces of DNA being pulled in an electric field toward the positive end of the field, causing a comet like tail. The longer the tail the more the DNA damage and this correlated with patients who were ultimately diagnosed with cancer(58) and precancerous conditions (58) and those who were healthy (94). Further clinical research is evaluating the tests accuracy.

Are Women Treated for PreCancerous Cells on the Cervix, at Greater Risk of Later Cervical and Vaginal Cancers?

Friday, January 24th, 2014


A new study published in the British Medical Journal concluded that women previously treated for abnormal cells on the cervix (CIN3 or cervical intraepithelial neoplasis grade 3) are at increased risk of developing and dying from cervical or vaginal cancer compared with the general female population and that the risk rises after age 60. This is the first study to evaluate the risk of death from cervical cancer after treatment of CIN3) as women age. Data was used from the Swedish Cancer Registry that contains information on 150,883 women with CIN3 and of these, 1,089 had a diagnoses of invasive cervical cancer and 127 had a diagnosis of vaginal cancer whereas 302 and 52 respectively died of these diseases.

Results showed an increase risk of invasive cervical and vaginal cancers as women once treated for CIN3 grew older and the risk compared to women in the general population accelerated after age 60. By age 75 the incidence rates increased further and rates exceded 100 per 100,000 women over that age. Also the more recent the treatment of CIN3 the higher the risk of cancer.

Despite the risk involved, the researchers said women treated for ?CIN3 are well protected from cervical cancer and only a minority ot those treated die from the disease and women treated are assumed to have been followed up more closely than other women. They concluded that the treatment for CIN3 is very beneficial for women with the diagnosis but the risk of developing cervical or vaginal cancer and of dying from one of these among women previously treated for CIN3 is strongly increased after the age of 60 and 70 respectively, compared to the general population of women. . Also found was that treatment later in life increases the risk and they recommended that women previously treated for CIN3 be followed later in life.