Posts Tagged ‘risk’

Does Breast Cancer Increase the Risk of Thyroid Cancer?

Wednesday, March 11th, 2015

Does Breast Cancer Increase the Risk of Thyroid Cancer

Risk of Thyroid Cancer: New research presented at the 97th Annual Meeting of the Endocrine Society concluded that breast cancer survivors are at increased risk of thyroid cancer especially within 5 years of the breast cancer diagnosis. Data used included 704,402 patients with only breast cancer, 49,663 patients with only thyroid cancer, and 1,526 patients who developed thyroid cancer after breast cancer between the years 1973 and 2011.  Those who had breast cancer followed by thyroid cancer were younger on average when diagnosed with breast cancer than those with breast cancer alone; were more likely to have invasive ductal carcinoma; a smaller focus of cancer; and to have received radiation therapy. There was no difference in risk of having hormonal positive or had spread to lymph nodes in the two groups. When compared to those with thyroid cancer alone, those with breast cancer followed by thyroid cancer were more likely to have a more aggressive type of thyroid cancer, but the cancers were smaller in size, and fewer patients required additional radioactive iodine treatment. Patients with breast cancer followed by thyroid cancer were older than those with thyroid cancer only by 65 vs 45 years and the median age for developing the thyroid cancer following breast cancer was 5 years. The researchers recommended that breast cancer patients who receive radiation therapy be followed closely for 5 years.

Can Fat in the Diet Increase the Risk of Breast Cancer?

Wednesday, April 16th, 2014

logo1267406_mdA new study published in the Journal of the National Cancer Institute concluded that a high total and saturated fat intake are associated with a greater risk of estrogen receptor-and progesterone receptor-positive (ER+PR+) breast cancer and human epidermal growth factor 2 receptor- negative (HER2-) disease. Previous data on this association has been conflicting . In this study researchers prospectively analyzed data from over 10,000 breast cancer +patients with 11.5 years follow up. This data was taken from a larger cohort study of over 337,300 women living in 10 European countries , that created a  heterogeneous cohort in terms of geography-related dietary  fat intake patterns and molecular subtypes. These were seen as possible factors resulting in conflicting data from previous studies. Dietary questionnaire data was used  with the sample.  Results showed that high total and   high saturated fat intake were associated with greater risk of ER+PR+breast cancer. High saturated fat intake was associated with greater risk of HER2-disease.Researchers concluded “a high-fat diet increases BG risk and, most conspicuously, that high saturated fat intake increases r=risk of receptor-positive disease, suggesting saturated fat involvement in the etiology of receptor-positive BC.”

Can physical activity reduce the risk of breast cancer for all women?

Wednesday, March 26th, 2014

logo1267406_mdA new study reported at the ninth European Breast Cancer Conference concluded that practicing sport for more than an hour daily reduces the risk of breast cancer of women at any age, weight or geographical location. When compared to women with the least physical activity they lowered their risk by 12%.  These results were based upon a mega analysis of 37 studies  published between 1987 and 2013 and including over 4 million women.  Although results varied by tumor type  the overall rates by amount of physical activity were encouraging. In women on hormone replacement (HRT) the protective effects of physical activity did not show up but increasing awareness of the side effects of this intervention means increasing numbers of women using HRT  will decrease and probably influence future statistics on the relationship.

Is Running Better Than Walking for Breast Cancer Survival?

Wednesday, February 5th, 2014

logo1267406_mdA new study published in the International Journal of Cancer concluded that exceeding the recommendations for walking )(2.5 hours of moderate intensity physical activity per week)  for breast cancer survivors may provide greater probability of survival and that running may be better than walking.

In the study 986  breast cancer survivors were followed and walkers and 13 of the 272 runners died of breast cancer over 9 years. 33 of the 714  analyzing the two groups together a risk of breast cancer mortalituy decreased an average of 24% per metabolic equivalent (MET) hours per day of exercise, where one MET hours equals a little less than a mile of brisk walking or about two-thirds of a mile of running.

Looking at the runners and walkers separately, there was significantly less mortality in those who ran than th0se who walked. The runners risk for breast cancer mortality decreased over 40% per MET hour per day and those that averaged over 2 and a quarter miles per day were about 95% lower risk for breast cancer mortality than those that did not meet the recommended for exercise. In contract, the walkers risk for breast cancer mortality decreased 5% per MET hour per day that was not significant.

Researche4rs cautioned that the numbers of subjects in the study were small so results should be viewed cautiously but do believe exceeding the recommendations for exercise do reduce risk of breast cancer mortality and than running may be better than walking. He said }”If I were a breast cancer survivor, I would certainly consider running or some other vigorous exercise over walking. and I wouldn’t just be doing the minimum, with the consequences and potential benefit being so great.”

Can Olive Oil Help Prevent Breast Cancer?

Friday, January 31st, 2014

logo1267406_mdA new  report in the Syracuse National Health Examiner discusses research being carried out in Houston Medical Hospital on the use of olive oil to prevent breast cancer in women at increased risk for the disease. In this study they will look at changes in breast density that is known to be correlated with breast cancer before and after one year of treatment with olive oil.  The primary purpose of the study is to show a significant decrease in breast density with olive oil consumption.  The researchers said “We know there a correlation between breast density and breast cancer. A decrease in density of one percent can potentially translate into a nearly two percent reduction risk of developing breast cancer. ”

In the study, 50 premenopausal and 50 postmenopausal women are to be enrolled. Each subject will take one 25 mg hydroxytyrosol capsule for 12 months and undergo checkups every three months. The hope of the research is to offer women a healthy supplement that can help lower the risk of breast cancer.

Does Treatment for Hodgkin’s Disease Increase a Woman’s Risk of Breast Cancer?

Thursday, January 30th, 2014

logo1267406_mdA new study reported in Deutsches Arzteblatt International  concluded that girls treated with radiotherapy for Hodgkins disease during adolescence acquire a considerable risk of developing breast cancer based upon long term observational data/Five hundred ninety girls were followed for secondary breast cancer from 1978 to 1995 for a long period of time (average 17.8 years, maximun 33 years). Researchers estimated 19% of the girls treated with radiotherapy for Hodgkin’s disease developed secondary breast cancer within 30 years as a result of that therapy.  Because of these findings this high risk population is now evaluated by a structured screening program for breast cancer. The researchers recommended that when supradiaphragmatic  radiotherapy is necessary in girls over the age of 9, the parts of the chest exposed to the radiation should be kept as small as medically necessary to keep the risk of secondary breast cancer as low as possible.

Are Women Treated for PreCancerous Cells on the Cervix, at Greater Risk of Later Cervical and Vaginal Cancers?

Friday, January 24th, 2014


A new study published in the British Medical Journal concluded that women previously treated for abnormal cells on the cervix (CIN3 or cervical intraepithelial neoplasis grade 3) are at increased risk of developing and dying from cervical or vaginal cancer compared with the general female population and that the risk rises after age 60. This is the first study to evaluate the risk of death from cervical cancer after treatment of CIN3) as women age. Data was used from the Swedish Cancer Registry that contains information on 150,883 women with CIN3 and of these, 1,089 had a diagnoses of invasive cervical cancer and 127 had a diagnosis of vaginal cancer whereas 302 and 52 respectively died of these diseases.

Results showed an increase risk of invasive cervical and vaginal cancers as women once treated for CIN3 grew older and the risk compared to women in the general population accelerated after age 60. By age 75 the incidence rates increased further and rates exceded 100 per 100,000 women over that age. Also the more recent the treatment of CIN3 the higher the risk of cancer.

Despite the risk involved, the researchers said women treated for ?CIN3 are well protected from cervical cancer and only a minority ot those treated die from the disease and women treated are assumed to have been followed up more closely than other women. They concluded that the treatment for CIN3 is very beneficial for women with the diagnosis but the risk of developing cervical or vaginal cancer and of dying from one of these among women previously treated for CIN3 is strongly increased after the age of 60 and 70 respectively, compared to the general population of women. . Also found was that treatment later in life increases the risk and they recommended that women previously treated for CIN3 be followed later in life.

Are There Any Second Hand Effect from Electric Cigarettes?

Wednesday, December 18th, 2013

logo1267406_mdA new study published in Nicotine and Tobacco Research concluded that electronic cigarettes used indoors may involuntarily expose non-users to nicotine.

When users take a puff , a nicotine solution is heated, and the vapor is taken into the lungs. Researchers examined the vapor from 3 different brands of e-cigarettes using a smoking machine in controlled exposure conditions. They also compared secondhand smoke exposure from e-cigarette vapor and tobacco smoke generated by dual users.

Results showed that e-cigarettes emit significant amounts of nicotine, but not much carbon monoxide and toxic volatile organic compounds. The amount of secondhand nicotine varied by the brand and were lower than that produced by conventional tobacco cigarettes. The U.S., Surgeon General found no safe level of secondhand smoke from tobacco but has not evaluated the health risk of secondhand risk of cigarette vapor.

Researchers believe this is one of the few studies on secondhand risk of e=cigarettes and said the exposure to nicotine is 10 tiumes less than from tobacco smoke. However, additional research is needed to evaluate effects of secondhand smoke of e-cigarette vapors on vulnerable populations such as pregnant women and children and the effect on the smokers themselves.

Can High Cholesterol Fuel the Growth and Spreqd of Breast Cancer?

Wednesday, December 4th, 2013

logo1267406_mdA new study published in the journal, Science, concluded that a by-product of cholesterol functions like the hormone estrogen to fuel the growth and spread of the most common types of breast cancer. Researchers also found that anti-cholesterol drugs like statins seem to reduce the effects of the estrogen-like molecule.

These early findings used a mouse model (that are highly predictive of what occurs in humans)  andtumor cells the study explained the link between high cholesterol and reast cancer, especially in post menopausal women. The research also shows that dietaqry changes and /or therapies to reduce cholestero0l may offer a simple, accessible way to reduce breast cancer risk. The researchers said -“What we have found is a molecule—not cholesterol itself, but an abundant metabolite of cholesterol–called 27HC that mimics the hormone estrogen and can independently drive the growth of breast cancer/” The hormone estrogen feeds an estimated 75% of all breast cancers and 27HC behaves similarly toestrogen in animals.

Researchers said “The worse the tumors, the more they have of the enzyme” (that makes the 27HC molecule. More studies are planned.

Can Having Breast Cancer Increase Your Risk of Another Cancer?

Wednesday, October 23rd, 2013

logo1267406_mdAccording to a study published in the journal Gynecologic Oncology women diagnosed with invasive breast cancer are 39% more likely to develop a second cancer in a different part of the body. They further say that the increased risk may be due to the similar risk factors involved in both cancers, or to the side effects of the treatment received by breast cancer patients.

In the study, researchers studied 5.897 cases of invasive breast cancer diagnosed between 1985 and 2007 in women in Granada. Three hundred fourteen of these women developed a second primary cancer. The researchers also studied 22.814 additional cases of cancer affecting all parts of the body except the breast and all were diagnosed in the same time period and as part of the same study population. Of these women, 171 developed a second cancer that was in the breast.

Results showed that women under age 50 who had previously suffered from breast cancer were almost twice as likely to develop a second cancer than the general population (the risk was 96% greater). In women over the age of 50, a second cancer was 29% more likely. The risk of developing a second ovarian cancer was found to be almost five times higher among young women diagnosed with breast cancer than among the general population. In addition, both age groups were found to be at greater risk of developing non-melanoma skin cancer. They also found that the risk of developing a second cancer in the first five years following a diagnosis of breast cancer was high, and almost 3.5 times higher than that faced by other women. However, the risk of developing a second cancer five years or more after the first diagnosis was not significantly higher than for those without previous cancers.