Posts Tagged ‘simple test’

One dollar blood test using gold nanoparticles more effective than PSA test in prostate cancer detection.

Wednesday, April 8th, 2015

Prostate Cancer Detection with gold nanoparticles

A new study published in ACS Applied Materials & Interfaces concluded that a test using gold nanoparticles to detect early stage prostate cancer costs less that $1, has results in minutes and is more accurate than standard PSA screening. The gold particles attract cancer bio markers. The researchers test detects the immune response that the body produces in response to the development of a tumor. The gold nanoparticles are about 10,000 times smaller than a freckle.  When blood from a finger prick is mixed with the gold nanoparticles, certain cancer biomarkers cling to the surface of the tiny particles. increases their size and causes them to clump together. In the test they are able to measure the size of the particles by analyzing the light thrown off and the size reveals whether or not the patient has prostate cancer and how advanced it may be. Researchers said “Whats different and unique about our technique is it’s a very simple process, and the material required for the test is less than $1. And because it’s low cost, we’re hopinf most people can have this test in their doctor’s office. If we can catch this cancer in its early stages, the impact is going to be big.”

Evaluation of the test determined at 90 to 95 percent that it is not false positive, and with 50% confidence that it is not false negative which is higher than the PSA confidence in false positive at 20%. More research is planned with the eventual goal of hqving a simple, cheap test for various cancer types.

Can a Simple At Home Test Detect Colorectal Cancer?

Wednesday, February 12th, 2014

logo1267406_mdA new study in the Annals of internal Medicine reported that a simgle stool sample collected by patients at home and sent to a lab for analysis  will detect 79 percent of colorectal cancers. The researchers said “We know the FIT is easy to use, and now we also know this tool is a great tool for assessing which patients have cancer and which patients don’t.” The test has been recommended since 2008 but many people still do not know about it. And unlike other older stool tests, it does not require people to restrict their diets or to stop taking medications. The test detects small amounts of blood in the stool and those who test positive are more likely to have colorectal cancer and need to be followed up with a colonoscopy.

The evidence review for FIT . showed the test was quite sensitive and on average, detects 79 percent, or about 4 or 5 cancers with only one round of testing. It was also quite specific, on average, identifying 94 percent of those who did not have cancer who actually did not have cancer. For comparison, the at home test for fecal occult blood (FOBT) detects only about 13 to 50 percent of cancers after a single round of testing. This test also required three stool samples and also had dietary and medication restrictions.  For the FIT three stool specimens do not detect better than one. Nineteen studies were reviewed.

Simple Two Minute Questionaire May Lead to Better Early Detection for Ovarian Cancer

Wednesday, September 26th, 2012

A report in the Open Journal of Obstetrics and Gynecology concluded that a simple three question paper and pencil survey,  given in the doctor’s office and taking less than 2 minutes can effectively identify those women who experience symptoms that may indicate ovarian cancer. Questions were asked about the frequency  and duration of the following three symptoms: abdominal or pelvic pain, feeling full quickly and/or unable to eat normally, and abdominal bloating and/or increased abdominal size.

1200 women, age 40 to 87 were included in the sample and more than half reported being post-menopausal and about 90% were white. About half of the sample had been seen for routine care such as mammography and the other half were seen for current health concerns or follow up of earlier health problems. Five percent of the sample had positive scores on the test indicating a need for follow up. Of this group of 60 women one was with ovarian cancer shortly thereafter. Of the 95% of women who tested negative on the test, none developed ovarian cancer over the next twelve months. The authors said “Women with symptoms that are frequent, continual and new to them in the past year should talk to their doctor, as they may be candidates for further evaluation with ultrasound and blood tests that measure markers of ovarian cancer such as CA-125. ” Recent research indicates that approximately one in 140 women with symptoms may have ovarian canccder. Aggressive follow-up of these symptoms can lead to diagnosis when ovarian cancer can be caught earlier and more effectively treated.”