Cannabis/Chris Conrad & Constance Finley

May 14th, 2017

C Conrad

Chris Conrad (born March 10, 1953) is an American author, activist, curator, publisher and court-recognized expert in cannabis cultivation and use. He has played a key role in the shaping of the modern industrial and medical cannabis reform movements as the author of such seminal books as Hemp: Lifeline to the Future (1993) and Hemp for Health (1997), as well as through his activist work as the co-founder and first President of the Hemp Industries Association (HIA), founder of the Business Alliance in Commerce and Hemp (BACH), and the signature gathering coordinator for the Proposition 215 volunteer effort which made California the first US state to legalize the medical use of cannabis.[1] The December, 1999 issue of High Times ranked Conrad #10 on its list of top 25 “living legends in the battle for legal cannabi

Conrad’s writing career began when he designed and edited a revised edition of the hemp prohibition classic The Emperor Wears No Clothes by Jack Herer in 1990. He followed this with the publication of Hemp: Lifeline to the Future (1993), which was subsequently translated into Italian, and Hemp for Health (1997),[6] which was subsequently translated into Spanish Portuguese, Czech and German. He is also the author of Cannabis Yields and Dosages (2004) and Nostradamus and the Attack on New York.

Conrad has co-authored two books with collaborators Virginia Resner and his wife Mikki Norris: Shattered Lives: Portraits From America’s Drug War   and Human Rights and the US Drug War.

In 2007, Conrad contributed a chapter on cannabis history to Pourquoi & Comment Cultiver Du Chanvre by Michka,[12] where his writing appeared alongside contributions from other notable authors such as Jorge Cervantes, Raphael Mechoulam and Stephen Jay Gould.

In 1989, Conrad and his wife Mikki Norris co-founded the American Hemp Council, with the purpose of educating the American public on the many uses of industrial hemp and the laws against the crop in the United States.

In 1996, in the final weeks of the campaign (after the money came in and he was hired to do so), Conrad became the signature-gathering coordinator for the volunteer effort to pass California’s Proposition 215, the initiative which would go on to make the state the first in the US to legalize the medical use of marijuana.[14] He was also a vocal supporter of California’s Proposition 19 in 2010, which came within four points of making California the first state to legalize all adult uses of cannabis.[

Conrad has also been active in the movement to legalize industrial hemp, serving as the first president of the Hemp Industries Association (HIA) and founding the Business Alliance of Commerce in Hemp (BACH).

Since 2007, Conrad has taught at Oaksterdam University’s Oakland, California campus, where he teaches the history and politics of cannabis.

In 1993 and 2000, Conrad curated and designed the Hash-Marijuana-Hemp Museum in Amsterdam, The Netherlands. In 1995, Conrad and his wife Mikki Norris partnered with Virginia Resner to create and curate the “Human Rights ’95: Atrocities of the Drug War” photo exhibit to put a human face on non-violent prisoners of the Drug War and to show how the Drug War operates through their stories. Launched at the Fort Mason Center in San Francisco on June 24, 1995 for the 50th Anniversary the United Nations, the exhibit was put in context of the UN’s Declaration on Human Rights. The grand opening presented a program called, “Give Drug Peace a Chance,” that included Ram Dass, Paul Krassner, Jello Biafra, Ngaio Bealum, New Riders of the Purple Sage, and Terence Hallinan. They toured with this exhibit for many years, creating smaller excerpted displays that were shown at libraries, universities, conferences, and events under the name “Human Rights and the Drug War.” From 2011 to the present, Conrad has curated the Oaksterdam Cannabis Museum in Oakland, California.In 2014, Conrad and his wife Mikki Norris were jointly awarded the Seattle Hempfest Outstanding Cannabis Activist Award in recognition of their writing and advocacy work.

In 2010, Conrad was the recipient of Oaksterdam University’s Lifetime Achievement Award.

In 2004, Conrad and Norris received the Outstanding Citizen Activism Award at the 2004 national NORML conference.

In 2001, Conrad and Norris received the Drug Policy Alliance’s Robert C. Randall Award for Achievement in the Field of Citizen Action, along with collaborator Virginia Resner, Randy Credico of the William Moses Kunstler Fund for Racial Justice and Nora Callahan of the November Coalition.

The above information was taken from Wikipedia where Chris is listed.

ConstanceFinley

Constance Finley, founder and CEO of Constance Therapeutics, was inspired by her own personal experience with a chronic illness. After nearly dying from the pharmaceuticals prescribed to help alleviate pain and inflammation caused by a rare autoimmune disease, Finley turned to medical cannabis for relief.

She quickly became fascinated with the science behind the medicinal benefits of cannabis. Studies have found that cannabinoids, like THC and CBD, are more effective when working in tandem with the entire phytochemical profile of the female cannabis flower versus working in isolation – what is known as “The Entourage Effect.” Based on her research, Finley became determined to make standardized, whole plant cannabis extracts that incorporate all the naturally occurring cannabinoids, terpenes and flavonoids in cannabis, and are safe for those with compromised immune systems.

Prior to Constance Therapeutics, Finley was founder and CEO of Housing Allies, Inc. She pioneered the use of tax credits to create high-quality, aesthetically delightful low-income housing for the working poor and ill, utilizing corporate investments motivated by financial tax benefits. Finley also worked as a clinical psychologist and taught psychology courses at Naropa University, Greeley Junior College and Lone Mountain College. She holds a Master of Arts in Clinical Psychology from the University of San Francisco, where she graduated first in her class, and a Bachelor of Arts in Eastern Studies and Psychology from Lone Mountain College, where she graduated summa cum laude.

Reduced Stem Cell/Vitamin A Deficiency

May 10th, 2017

Lack of a Vitamin A metabolite causes a loss of important stem cells according to new research published in Cell. This metabolite known as retinoic acid is essential in the process of activating and inactivating stem cells to regenerate cells. Specialized cells in the skin, gut, or blood have a short lifespan and require steady replenishment from adult stem cells that divide continuously. In 2008 it was discovered that a group of special stem cells in the bone marrow remain dormant most of the time and only become active to fight bacteria or viruses, durinmg heavy vlood loss, or as a result of chemotherapy. When their work is done these most potent stem cells return to dormancy. Current researchers found the mechanism that activate or deactive stem cells and that is the retinoic acid , a metabolite of vitamin A, that is crucial to the activation-deactivation process.

In the mice studies they found that stem cells are lost as a reservoir when they lack retinoic acid. Feeding the mice a diet deficient in vitamin A caused a loss of stem cells. This study added to those previously that showed vitamin A deficiencies impaired the immune system.

No Show Today

April 23rd, 2017

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Due to Computer and Health Issues I was unable to get a show together today. The scheduled show will be broadcast in two seeks. Sorry for any problems resulting.

Used Bemer Pro Wanted.

April 22nd, 2017

Malignant Melanoma

I am looking for a used Bemer Pro with minimal hours of use and still under warrently for my personal use. If you have one please contact me at  carlhelvie@cox.net or at (757) 848-=9193. Thank you.

BPA/Inflammatory Breast Cancer Connection.

April 12th, 2017

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The chemical bisphenol A (BPA) seems to aid the survival of inflammatory breast cancer cells that reveals a possible mechanism for how the disease grows according to new research in the journal Carcinogenesis. They found that BPA increases the cell signaling pathways known as mitogen-activated protein kinases (MAPK) in inflammatory breast cancer cells. Researchers said “the study is the first to show that BPA increases signaling thorough receptors that communicate with the MAPK pathway and that the presence of BPA may lead to resistance to cancer drugs targetinmg this pathweay. In our cell model, more signaling led to increased growth of the cancer cells”

Researchers started by treating Inflammatory Breast Cancer cells with six endocrine-disrupting chemicals commonly found in the everyday environment found in food, medicine and agricultural products. The found that BPA, in addition to chemicals trichloroethane (HPTE) and methoxychlor, caused an increase in signaling to epidermal growth factor receptors (EGFR), that lie on the cell surface. When cells were treated with low doses of BPA, there was nearly a doubling of EGER and signaling to the MAPK pathway also increased. This weas accompanied with a rise in indicators of cancer cell growth. They also found that BPA exposure inhibited the effectiveness of drugs that work to kill cancer cells by inhibiting EGFR signaling.  Research is ongoing.

Medical Marijuana Expert/Dr David Bearman

April 9th, 2017

 

 

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Dr David Bearman, M.D. is one of the most clinically knowledgeable physicians in the U.S. in the field of medical marijuana and will appear on the Holistic Health Show on Saturday.  He has spent 40 years working in substance and drug abuse treatment and prevention programs.  Dr. Bearman was a pioneer in the free and community clinic movement.  His career includes public health, administrative medicine, provision of primary care, pain management and cannabinology.

His almost 40 year professional experience in the drug abuse treatment and prevention field includes being the Co-Director of the Haight-Ashbury Drug Treatment Program, being a member of Governor Reagan’s Inter Agency Task Force on Drug Abuse, a member of both the Santa Barbara and the San Diego County Drug Abuse Technical Advisor Committees, and a consultant to Hoffman-LaRoche, Santa Barbara County Schools and the National PTA. He has been recognized by the Santa Barbara Medical Society with the Humanitarian Recognition Award.

Dr. Bearman is also the author of Drugs Are NOT the Devil’s Tools: How Discrimination and Greed Created a Dysfunctional Drug Policy and How It Can Be Fixed in 2 volumes. More information is available at: http://www.davidbearmanmd.com/

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Is High Dose Vitamin C safe?

April 5th, 2017

 

Holistic-Health-Show-with-Dr-Carl-O-HelvieA new study published in Cancer Cell researchers found in clinical studies that it was safe to regularly infuse brain and lung cancer patients with 800 to 1,000 times the daily recommended amount of vitamin C as a potential strategy to improve outcomes of standard cancer treatments. In addition, they showed pathways by which altered iron metabolism in cancer cells, and not normal cells, lead to increased sensitivity to cancer cell death caused by high dose vitamin C.

In the study 11 patients enrolled in the brain cancer safety trial and received three infusions of vitamin C a week for 2 months followed by two infusions per week for 7 months while receiving standard care of radiation and chemotherapy. The goal of each infusion was to raise the concentration of vitamin C in a patients blood to 20,000 uM, as compared to a blood level of          70 uM found in most adults. A high dose is necessary because vitamin C has a half life of around two hours in circulating human blood. The treatment was generally well tolerated except for frequent trips to the bathroom and dry mouth. (as an aside, dry mouth was the one symptom mentioned by Dr Francisco Contreras at the Oasis of Hope where they have used high dose vitamin C with cancer patients). Researchers found that occasionally patients had elevated blood pressure that subsided quickly following infusion.

The safety of the high dose vitamin C is due to the fact that it is not toxic to normal cells but when interacting with cancer cells the high levels of redox active iron molecules in the cancer cells reacts with the vitamin C to form hydrogen peroxide and free radicals formed from hydrogen peroxide. The free radicals are believed to cause DNA damage selectively in the cancer cells that lead to cancer cell death and sensitivity to radiation and chemotherapy in cancer cells. (This has been long known by alternative doctors who use the high dose vitamin C without the chemo and radiation).  Researchers said “This is a significant example of how knowing details of potential mechanisms and the basic science of redox active compounds in cancer versus normal cells can be leveraged clinically in cancer therapy.” …Here , we verified convincingly, that increased redox active metal ions in cancer cells were responsible for the differential sensitivity of cancer versus normal cells to very high doses of vitamin C.” Further studies on safety and vitam C are planned.

Ultrasound + Immunotherapy Cancer Treatment

March 31st, 2017

 

Holistic-Health-Show-with-Dr-Carl-O-HelvieA new study published in JCI Insight researchers showed that combining high-intensity focused ultrasound with two immunotherapies (a PD-1 checkpoint inhibitor and TLR9 agonist) can produce excellent response rates in mouse models of epithelial cancer and that the immunotherapies must come first for it to be effective.  Researchers sais “These combination protocols can achieve a complete response in a large fraction of solid tumors” We found that we could achieve responsea in distant leisions, but the specific protocol is really important.”

They said high-intensity focused ultrasound is a relatively new approach to destroying or reducing malignant tumors tumor in which the ultrasonic beam heats tumor tissue and kills the cancer cells in minutes. But the effect is localized abd the researchers hoped that by combining it with immunotherapy they could treat more systemically. In immunotherapy ,  the PD-1 inhibitor takes the brakes off  cytotoxic T-cells, releasing them to fight cancer with greater intensity.  The TLR9 agonist boosts dendrite cells and other immune components.

The researchers were relying on the abscopal effect of the ultrasound like observed in radiation theraoy patients. As cancer cells die, they release antigens that kick up the immune response, focusing T cells on the tumor and turning a local effect into a systemic one. Ultrasound also contributes by shrinking the tumor, making it more vulnerable to immune attack.

In their study, researchers tested the immunotherapy both before and after ultrasound to determine the more effective protocol. The found that immunotherapy before the ultrasound was the best approach and lead to a complete response in 80% of the mice after 90 days,. They said the study showed that early immunotherapy both expanded the T-cell population and primed them to respond-like a swarm of angry bees waiting for a target. “You get the immune response going and then you deliver the focal therapy.”  Thus, treating multiple tumor sites sequentially with ultrasound following immunotherapy was more effective than immunotherapy alone.  Researchers concluded “We know we need to personalize theres therapues and Were develoiping the tools that will help us do that.”

 

Cancer Development/Epigenetics/ Metabolism?

March 29th, 2017

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A new study published in Briefings in Functional Genomics evaluated how epigenetics modulate human genetic programs and how it emphasizes or silences genes and concluded that if epigenetics is disrupted. it might switch on oncogenes (genes that under certain circumstances transform cells into tumor cells) or shut down tumor suppressors. Both processes will transform cells into tumor cells and cause cancer.

Experiments carried out years ago showed that chemical modification affecting the packaging of DNA can switch genes on or off. Epigenetics evolved to explain the changes caused by modification of gene expression , instead of altering the gene code itself and focuses on factors that regulate how and when certain genes are turned on and off.  In contract, epigenomics relates to the analysis of global epigenetic changes across many genes. Current research shows that complementary forces of on and off switches keep each other is check. If one force overtakes, the system gets out of equibrium. and the cells either experience unlimited growth, cancer, or death. It is believed that a better understanding of these processes will lead to counter factors to prevent cancer.

 

Dr Carlos Garcia/Utopia Wellness Cancer Treatment

March 26th, 2017

Dr Carlos Garcia

Utopia Wellness is a leading-edge medical center that offers integrative, holistic, patient-focused medical treatments. Under the direction of Carlos M. Garcia, M.D., programs designed for anyone who wants to enjoy optimal health are offered: Whether suffering from a chronic illness or simply wanting to prevent disease. Our extensive menu of wellness programs complement each other by addressing all issues related to well-being.

Dr. Carlos M. Garcia M.D. received his formal medical training at the University of Massachusetts, Medical School followed by an internship in Internal Medicine and residency in Anesthesia, both at Hahnemann University in Philadelphia, PA.

After moving to the Tampa Bay area in 1984, he began his practice as an Anesthesiologist at Bayfront Medical Center, Edward White Hospital, and Physicians’ Community Hospital.

Over his years working in hospitals, he came to realize that traditional medicine was driven more by the profits of pharmaceutical companies and hospitals than it was on providing the patient with the best possible care. So in 1996, Dr. Garcia redirected his medical focus to natural alternative health care including holistic medicine, integrative cancer treatments, Chelation therapy, bio-identical hormone replacement, IV vitamins and antioxidants, and weight loss. In all of these areas, he uses non-harmful and natural alternatives to conventional treatments. His passion to help others achieve optimal health through natural medicine led him to found Utopia Wellness, where he incorporates the best that medicine has to offer, traditional and alternative.

Dr. Garcia’s focus over the past several years has been on helping people suffering from cancer and its related diseases. His approach is holistic in that he addresses not only the tumor or cancer but also on the whole person and the cause of the cancer. To be truly cancer free for life, you must identify and eliminate the underlying cause of the disease.  In 2012, Dr. Garcia published his book Cancer is a Symptom: The Real Cause Revealed where he addresses the prospect that cancer is merely a symptom and unless you heal the underlying cause, you will never be truly cancer free.He also co authored Cancer Free with Bill Henderson.

Dr. Garcia is a member of ACAM (American College for the Advancement of Medicine), ICIM (International College of Integrative Medicine), and the American Holistic Health Association.  Additionally, Dr. Garcia holds certifications in Chelation Therapy from the American Board of Chelation Therapy, and has given numerous lectures on various health topics to professionals, medical students and the public, has had a radio talk show, and has been interviewed for several health related television news topics.

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