Archive for the ‘diagnosing’ Category

Dr Sandra Goodman/Positive Health/Nutrition & Cancer

Sunday, June 18th, 2017

Sandra Goodman PhD, Co-founder and Editor of Positive Health PH Online, trained as a Molecular Biology scientist in Agricultural Biotechnology in Canada and the USA. Sandra was born and grew up in Montreal, Canada, a highly cosmopolitan city in Quebec, subject to the political tensions of the Canadian French and English divide. In addition to focusing upon her academic studies in the arts and sciences, Sandra was also a talented pianist and athlete, particularly in gymnastics. Having qualified as a Red Cross swimming instructor and Royal Lifesaving Society lifeguard, she greatly enjoyed teaching young adults and children to swim and overcome their fear of the water.

Sandra graduated with her PhD in Molecular Biology from McGill University with her Thesis: Expression of host genes in soybean root nodules, research attempting to identify nitrogen fixation genes in a legume, with an ultimate goal of being able to transfer such genes to non-legumes and reduce the requirement for fertilizer. Dr Goodman worked for a Multi-National Corporation in the USA as a Biotechnology Scientist until the mid-1980s, eventually traveling and settling in the UK focusing upon health issues. Author of 4 books regarding the role of Nutrition in empowering optimum health, including Nutrition and Cancer: State-of-the-Art, Vitamin C – The Master Nutrient, Germanium: The Health and Life Enhancer and numerous articles, Dr Goodman was the lead author of the Consensus Document: Nutritional and LifeStyle Guidelines for People with Cancer and compiled the Cancer and Nutrition Database for the Bristol Cancer Help Centre in 1993.

The catastrophic but flawed research paper in The Lancet in the early 1990s alleging that women with breast cancer attending the Bristol Cancer Help Centre (BCHC) were more likely to die than those undergoing conventional treatment almost led to the closure of BCHC. Having authored a scholarly article Nutritional and Lifestyle Guidelines for People with Cancer, Dr Goodman was then commissioned in the early 1990s to set up a Cancer and Nutrition database which would identify the published research papers in this field.

During the compilation of this database, drawn from some 5000 peer-reviewed research papers, it was suggested by Sandra’s long-term partner Mike Howell that there was a lack of communication of this type of research both to health professionals and the serious general reader of health information. Thus was born Positive Health magazine PH Online, which has now published over 237 issues (the print magazine ceased after Issue 150); the entire archive is exclusively online at www.positivehealth.com

Dr Goodman has worked for the past 22+ years as a co-founder and Editor of Positive Health PH Online in attempting to show that there is no divide between different types of healthcare, just different approaches, i.e. Integrated Medicine. She is passionate about making available to all people, particularly those with cancer,  research information and clinical expertise in the areas of Nutrition and Complementary Therapies. She has been a member of the Therapy Advisory Panel of the Penny Brohn Cancer Care, Scientific Expert Committee member of the Alliance for Natural Health and a Patron of the Avalon Complementary Medicine Trust in Wells, Somerset. Her recent (Oct 2014) Research Proposal: Cancer Patients’ Outcomes: Comparing Integrated Alternative Therapies and Chemotherapy / Radiotherapy Treatment reviews the scientific literature regarding chemotherapy toxicity.

Dr Goodman and her long-term partner Mike Howell seek individuals with the resources, structural organization and interest to continue and expand the legacy of Positive Health PH Online forward into the 21st century, adding facilities to conduct online seminars, fundraising for alternative cancer research, as well as to promote leading holistic organizations and businesses internationally. Follow her Blog and purchase Nutrition and Cancer: State-of-the-Art. Dr S Goodman may be contacted privately for Research, Lectures and Editorial services via:  sandra@positivehealth.com   www.positivehealth.com   sandra@drsgoodman.com  www.drsgoodman.com

Enjoy the Interview below:

 

 

 

Dr Fred Pescatore Speaks on Science Based Weight Loss

Sunday, June 4th, 2017

Interviews with Dr Fred and Kathleen O’Keefe  Kanovas available below.

Fred Pescatore, MD, is one of the most sought-after natural physicians in the country, specializing in making you feel like the best version of you! He will be the first guest on the Holistic Health Show on Saturday.

You may have already met Dr. Pescatore on The O’Reilly Factor, Rachael Ray, The Today Show, Extra, The View, and many more – sharing the latest breakthroughs in integrative and nutritional medicine.

Dr. Pescatore is the author of the New York Times best-selling book, The Hamptons Diet and the No. 1 best-selling children’s health book, Feed Your Kids Well, among others. Dr. Pescatore’s other books include: Thin For Good, The Allergy and Asthma Cure, The Hamptons Diet Cookbook, Boost Your Health with Bacteria and most recently the A-List Diet. 

Dr. Pescatore has his finger on the pulse of natural medicine’s most cutting-edge cures. As a result, everyone from normal hardworking Americans to international royalty are traveling hundreds (sometimes even thousands) of miles to visit at his renowned clinic in New York City.

He’s spent over 3 decades studying, researching and practicing medicine around the world alongside some of today’s most well respected physicians.

Through his non-stop research and unique medical connections across the globe he hears about the most groundbreaking natural discoveries and healing techniques as they happen…sometimes decades before they trickle out to the mainstream.

Dr. Pescatore has spoken on hundreds of radio shows across America. And for years, he was heard daily as the host of the No. 1 health radio show in New York City called, The Logical Alternative. He is currently on the editorial board of Us Weekly magazine and is a regular contributor to In Touch, First for Women and Women’s World magazines.

With over 30 years of knowledge in his back pocket, Dr. Pescatore is putting the research, techniques, and in-depth healing protocols right in your hands–and not in clunky medical textbook fashion. Dr. Pescatore makes good health easy to understand and attainable for any age, at any fitness level. His natural approach to healing confronts the modern day cure-all obsession for drugs and surgery that come with countless side effects. And it’s not just his patients that are reaping the benefits. Dr. Pescatore features it all in one of the most exclusive health newsletters available, Logical Health Alternatives. A direct pipeline to one of the most respected minds in natural medicine, written by Dr. Pescatore himself. These cutting-edge cures and simple healing miracles are also shared daily with his loyal readers in his free e-letter Reality Health Check.

Behind all the glitz and glamour, Dr. Pescatore is also deeply involved in the philanthropic community, devoting time to working in hospitals in Tanzania, as well as helping to support local organizations for the youth in this country. If he’s not lecturing across America or head deep in clinical research, he often travels around the world lecturing in such exotic locales as India and Japan – usually returning with new medical techniques to share with his patients.

After graduating medical school at Columbia University, Dr. Pescatore studied in Southeast Asia, India, Japan, Africa, and Europe. The techniques he gathered have become part of his broad knowledge of healing.

His passion for traveling and education has given Dr. Pescatore vast opportunity to research and create some of the best nutritional supplements available today. Coming out with his own line in 2012, NuLogic Nutritionals, Dr. Pescatore has had hands-on experience formulating only the highest quality ingredients derived from ideal climates around the world.

Because of the respect Dr. Pescatore has earned in the nutritional supplement industry, he is a consultant for many firms and has been instrumental in developing and clinically testing many of the leading nutritional products. He is the President of the International and American Associations of Clinical Nutritionists, a member of the American College for the Advancement of Medicine, and belongs to many other professional organizations.

Prior to opening his own practice, for five years, Dr. Pescatore was the Associate Medical Director of The Atkins Center for Complementary Medicine working as the right-hand-man to the late, great Dr. Robert C. Atkins

Grounded in the latest cutting-edge science, the A-List Diet is a foolproof approach to eating healthy that will make your body feel good on the inside, which makes you look younger, slimmer, and better than ever—the natural way.

With a unique dieting innovation known as amino boosting, the A-List Diet goes beyond Atkins, beyond The Whole 30, beyond Eat Fat, Get Thin, and way beyond Paleo. By combining the benefits of amino boosting, protein rotation, inflammation busting, alkalization, and genetics, this diet maximizes your ability to drop weight.  More information is available at: http://drpescatore.com/ 

Enjoy the Interview Below:

 

Kate Shemirani, R.N., Breast Cancer Survivor, Discusses Gerson Therapy Used

Sunday, November 6th, 2016

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My guest is Kay Allison Shemirani ( Kate) who was born November 30 1965 in Nottingham England. She was the youngest of 3 daughters. Her father was a local postman and her mother a secretary. She grew up in an average working class environment with state schooling. In 1984 age 18, She began her nurse training in Glasgow Scotland.  Upon qualifying she worked in several clinical areas… Gynaecology, theatres, trauma.  In 1990 she began working as a long haul air stewardess traveling the world and continued to work as a nurse on rest days.

In 1996 she married and had 4 children in quick succession. 3 were with IVF. They are now age 17,15,15,13. With 2 boys, and 2 girls she became a full Time mum from 2001 until 2009. After all 4 children were in school she returned to the University to re-register as a nurse and then obtain trained in Aesthetics and opened her own business.

On February 12th 2012, Kate was diagnosed with breast cancer and followed the Gerson therapy for 2 years. During this time she studied constantly and obtained a diploma in personal nutrition, Cancer, and alternative therapies.

In 2014 she separated from her husband and today lives in East Sussex south England with her 4 children and 7 rescued cats. She loves to go for long walks at the beach and in the Sussex countryside and works as a practitioner advising patients on diet and lifestyle to heal degenerative disease. Her passion is for everyone to make truly informed healthcare choices. She will discuss her cancer journey with us. More information:  www.gersonuk.com 

Enjoy the interview below:

 

Breast Cancer Risk Assessment.

Wednesday, April 13th, 2016

 

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A new study in the April 1 issue of Cancer Research reported that women were five times more likely to develop cancer if they had a higher percentage of Ki67, a molecule marker that identifies proliferating cells, in the cells that line the mammary ducts and milk producing lobules. These mammary epithelium cells, undergo drastic changes throughout a woman’s life, and are the location of the majority of breast cancers. Healthy breast tissues the percentage of cells expressing molecular marker Ki67 and p27 was low.

Researchers examined biopsies with some as old as 4 decades earlier, from 302 subjects who had been diagnosed with benign breast disease. They compared tissue from 69 women who later developed cancer to the tissue from the 233 women who did not. Researchers found that those with a higher percentage of Ki67 were five times more likely to develop cancer. Doctors currently test breast tumors for Ki67 levels, yo make decisions about treatment but this was first time Ki67 has been linked to precancerous tissue and used as a predictive tool. Researchers said ” Instead of only telling women that they don’t have cancer, we could test the biopsies and tell women if they were at high risk or low risk for developing breast cancer in the future. ”

Currently, mammograms are considered the best  tool for early detection of breast cancer but there are risks associated with this method including psychological distress, delayed treatment, or over treatment due to false positive and negative results and over diagnosis. In addition mammogram machines use low dose radiation anfd repeated screening can potentially cause cancer.  “If we could minimize unnecessary radiation for women at low risk, that would be good” according to one of the researchers. They further say screening for Ki67 levels would be easy to carry out currently but the researchers want to replicate the results in an independent cohort of women first.

Can RNA in Platelets Diagnose and Classify Cancer and Identify Treatment Strategies?

Wednesday, November 4th, 2015

Logos 005A new study published in the journal Cancer Cell, concluded that from an analysis of tumor RNA  carried in platelets, that play a role in clotting, may be more useful than other liquid biopsy technologies for diagnosing cancer and determining its primary location and potential therapeutic approaches. The researchers found that platelets that have taken up tumor RNA can distinguish among blood samples of healthy individuals and those of patients with six types of cancer. determine the location of the primary tumor, and identify tumors carrying mutations that can guide therapeutic decision making. Researchers said “By combining next-generation sequencing gene expression profiles of platelet RNA with computational algorithm Platelet  we developed. we were able to detect the presence of cancer with 96% accuracy.” …..”RNA signatures also provide valuable information on the type of tumor present in the body and can guide selection of the most optimal treatment for individual patients.” Results were based upon isolated platelets from blood samples taken from 55 healthy individuals, 39 individuals with early stage cancer and 189 patients with advanced metastatic cancer. Patients had either small-cell lung cancer, colorectal cancer, glioblastoma, pancreatic cancer, hepatobiliary cancer or breast cancer.

After analyzing a drop of blood from each individual researchers found more than 5,000 different platelet RNAs. Comparing RNA profiles of healthy individuals with those of cancer patients showed increased levels of almost 1500 RNA molecules–many involved in cancer-associated processes–and reductions of almost 800 in samples from cancer patients. Examining levels of about 1,000 RNAs from almost 300 individuals with the algorithms that classified whether of not cancer was present did so with 96% accuracy. All of the patients with localized tumors and 33 or the 39 with tumors of the central nervous system were accurately diagnosed. Platelet RNA profiles also correctly identified the particular type of cancer in each patient. Research is ongoing.

Do More Examiners Reviewing Results of Mammograms Improve Efficacy of Breast Cancer Detection?

Wednesday, August 19th, 2015

logo1267406_mdA new study published on Medical Express concluded that five independent assessments lead to better results than one or two. Previous researchers found that usually one or even two physicians in Europe review x-rays from mammograms but even when two review them, results are often wrong. About 20% of women with cancer are diagnosed as being cancer free, and about 20 % of those who are cancer free and diagnosed as having cancer. This lead to the study to evaluate collective vs individual intelligence for efficacy when reviewing x-rays.

Using a data set with a large number of mammograms with an independent assessment of each by about one hundred radiologists  as well as the actual health status with a yes or no for cancer on all patients. They found that five independent assessments lead to better results. Simple collective rules such as majority vote or quorum vote in order integrate the vote was used. Compared to the best physician, a collective intellectual vote allowed both the false positives and false negatives from mammograms to be reduced (sensitivity and specificity) ie: cancer diagnosis but no cancer and no cancer diagnosis but cancer. The collective benefit of mammograms begins to occur when three or four physicians are used for the assessment but the benefit of additional assessments significantly start to level off at about 8 or 10 assessments according to the researchers.

New Program Improves Lung Cancer Detection

Wednesday, July 22nd, 2015

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A new study on lung cancer detection presented at the American Thoracic Society International Conference in Denver concluded that long-time smokers and past smokers now have a more accurate way to detect whether or not they have lung cancer using CT scan technology. The study compared CT scans and standard chest x-rays to detect lung cancer. CT scans obtain a multiple-image scan of the entire chest, whereas a standard chest x-ray produces a single image of the whole chest. Results showed that patients receiving CT scans had a 15 to 20 percent lower risk of dying compared to those receiving standard chest x-rays.

The comparative study took place between September, 2014 and March, 2015 and gave CT scans to 375 patients of which 272 were eligible to continue in the program. Of this 272 patients, 19 had results that indicated malignant cancer.  Of those 19, 11 were confirmed malignant.  Eight of the 11 had lung cancer, and 3 had early stage lung cancer. Patients enrolled in the lung cancer detection program were considered high risk for lung cancer and all had a smoking history of at least 30 pack years that is the equivalent of smoking one pack of cigarettes a day for 30 years, and were current or former smokers without any signs or symptoms of lung cancer. The researchers said finding 3 early stage lung cancer patients  in the first 357 patients screened is incredible. Implementation of this program should save lives.

Can Imaging Techniques Identify Early Metastasis in Lymph Nodes?

Wednesday, May 27th, 2015

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A study published in Cancer Research concluded that a highly sensitive imaging technique for non-invasive screening of lymph nodes for metastatic cancer has been developed that offers a rapid tool for noninvasive identifying cancer spread at its earliest stages based upon testing in mice. The technique uses an imaging approach known as ultrasound-guided photoacoustics combined with nonosensors designed to target and identify metastatic cells in lymph nodes.

Over 90% of cancer deaths can be attributed to metastases directly or indirectly. Currently an invasive surgical procedure called sentinel lymph node (SLN) biopsy is used to identify the region and spread of tumors but the procedure has adverse side effects including pain, numbness and risk of infection. Noninvasive imaging modalities have been tested in animals and patients in order to improve the accuracy and safety of lymph node biopsies. Some imaging techniques such as position emission tomography (PET) and magnetic resonance imaging (MRI) have shown some potential but lack the specificity and sensitivity to be effective. The new technique seems to be more accurate and have improved  sensitivity. Overall, the testing in mice showed a sensitivity of 100% and a specificity of 87% for detection of lymph nodes micrometases as small as 50 micrometers, which corresponds to about 30 metastatic cells. Detection of cells in small numbers in lymph nodes offers a system having the ability to identify metastasis very early in the process, which would allow early treatment. Although these are early studies in mice, the researchers are optimistic about translating the technology for use in humans and expanding the use of the system. More research is planned.

Improving the Accuracy of Clinical Breast Exams.

Wednesday, February 25th, 2015

Improving the Accuracy of Clinical Breast Exams

A new study in the New England Journal of Medicine concluded that sensor technology has the potential to significantly improve the teaching of proper techniques for clinical breast exams. In the study researchers asked 553 practicing physicians during an annual clinical meeting to perform simulated clinical breast exams (CBE) under conditions that mimic an office visit for a symptomatic patient. participants completed a demographic survey, reviewed a clinical senario, performed the CBE on a sensor-enabled breast model, and then documented their findings. Researchers hoped to capture CBE technique while clinicians were evaluating the model for a mass. Results showed that physicians who palpated fewer than 10 newtons (a common measurement of force) were able to find two superficial masses on the breast model but missed the two deeper ones. Physicians increasing the amount of palpable pressure unproved the probability of identifying the deeper lesions. It was suggested that the optimum palpable force for deeper lesions is between 12 and 17 newtons. Researchers found that 15 percent of physicians in the study used a technique that put them at significant risk of missing deep tissue lesions near the chest wall. Researchers suggested considering mastery training in the health care professions to overcome this problem.

Can Prostate Cancer be Confirmed Without a Biopsy”

Wednesday, August 13th, 2014

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The Prostate Health Index (phi), a simple, non-invasive blood test that is three times more specific than the PSA to detect prostate cancer is now available according to a report in Science Digest. This may reduce the need for men who test positive for prostate cancer using  a PSA test  to need  a biopsy. Researchers said “The PSA test is based on the fact that men with higher levels of PSA protein are more likely to have prostate cancer.” “However. the problem is that higher levels of PSA can also be caused by a benign enlargement or inflammation of the prostate, leading to many false positives for cancer and ultimately unnecessary invasive biopsies and an increased potential for patient harm.”  Because the blood test is three times more specific in detecting prostate cancer than the PSA it may reduce the need for a biopsy and potential patient harm. Studies showed a reduction of 31% in unnecessary biopsies due to false positives on PSA’s using the phi test.

The phi test uses three different PSA markers as part of a sophisticated algorithm to increase the reliability of determining a patient with a positive PSA has prostate cancer. “The Prostate Health Index is a significant addition to our comprehensive menu of advanced clinical evidence based blood tests that aid in early cancer detection.” said the co-founder of the laboratory offering the test.