Posts Tagged ‘breast cancer’

One alcohol drink daily raises breast cancer risk!

Wednesday, May 31st, 2017

One alcohol drink a day (small glass wine or beer-10 gms alcohol) increases pre-menopausal breast cancer risk by 5 percent and post-menopausal breast cancer risk by 9 percent according to new research reported by the American Institute for Cancer Research and the World Cancer Research Fund. Researchers also found that vigorous exercise such as running or fast bicycling decreases the risk of both pre and post-menopausal breast cancer ,They also confirmed earlier findings that moderate exercises decrease the risk of post-menopausal breast cancer that is the most comm,on type of breast cancer. Researchers said “With this comprehensive and up to date report  the evidence is clear, Having as physically active lifestyle, maintaining a healthy weight throughout life and limiting alcohol–these are all steps women can take to lower their risk.”

This report analyzed 119 studies, including data on 12 million women and 260,000 cases of breast cancer. The study found the equivalent of 10 gm of alcohol a day increased the risk and the standard drink is 14 gm of alcohol. specifics of exercise and cancer risk found follow: pre-menopausal women who were the most active had a 17 percent lower risk and post-menopausal women had a 10 percent lower risk of developing breast cancer compared to those who were the least active. Moderate activity such as walking and gardening gave a 13 percent lower risk when compared to the most vs least active women for developing cancer.

Other findings included: being overweight or obese increases the risk of post-menopausal breast cancer; women who breast fed were are lower risk of breast cancer; and the great adult weight gain  the greater the post-menopausal breast cancer risk.  There was limited evidence for the following findings that must be repeated, 1) non-starchy vegetables lower the risk for estrogen-receptor (ER) negative breast cancer that is a less common but a more challenging type to treat. ) 2) dairy, diets high in calcium and foods containing carotenoids seemed to lower risk of breast cancer. Carrots, apricots, spinach and kale are all foods high in carotenoids and should be studied for their health value;

Kate Shemirani, R.N., Breast Cancer Survivor, Discusses Gerson Therapy Used

Sunday, November 6th, 2016

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My guest is Kay Allison Shemirani ( Kate) who was born November 30 1965 in Nottingham England. She was the youngest of 3 daughters. Her father was a local postman and her mother a secretary. She grew up in an average working class environment with state schooling. In 1984 age 18, She began her nurse training in Glasgow Scotland.  Upon qualifying she worked in several clinical areas… Gynaecology, theatres, trauma.  In 1990 she began working as a long haul air stewardess traveling the world and continued to work as a nurse on rest days.

In 1996 she married and had 4 children in quick succession. 3 were with IVF. They are now age 17,15,15,13. With 2 boys, and 2 girls she became a full Time mum from 2001 until 2009. After all 4 children were in school she returned to the University to re-register as a nurse and then obtain trained in Aesthetics and opened her own business.

On February 12th 2012, Kate was diagnosed with breast cancer and followed the Gerson therapy for 2 years. During this time she studied constantly and obtained a diploma in personal nutrition, Cancer, and alternative therapies.

In 2014 she separated from her husband and today lives in East Sussex south England with her 4 children and 7 rescued cats. She loves to go for long walks at the beach and in the Sussex countryside and works as a practitioner advising patients on diet and lifestyle to heal degenerative disease. Her passion is for everyone to make truly informed healthcare choices. She will discuss her cancer journey with us. More information:  www.gersonuk.com 

Enjoy the interview below:

 

New Method for Killing Metastatic Breast Cancer Cells.

Wednesday, August 31st, 2016

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A new study to be published in Clinical Cancer Research discusses a new way to kill breast cancer cells that are metastasizing  and these cells that spread to the brain, lungs, and bones are the leading cause of death for most cancer patients.  The research discovered how the cells moving to other areas of the body are killed by peptide CT20 that she discovered in 2012.  The peptide CT20 kills the cells by disrupting the folding mechanism inside cancer cells mediated by chaperonin and if the folding mechanism into 3D units is disrupted the cell dies.  Metastatic breast cancer cells have high levels of the chaperonin and the higher the levels the sicker the patient. Multiple strategies can be developed for fighting metastatic cancer cells because of the discovery of how the peptide inhibits the chaperonins folding ability and subsequently  kill cancer cells.  The amount of the peptide that kill cancer cells do not kill normal healthy, non-cancer cells so there will be less traumatic side effects compared to most chemo therapies. A nanoparticle was developed to transport the peptide specifically to metastatic cancer cells.

SEVA Therapeutics, a Massachusetts-based pre-clinical biotechnology company, has licensed the nanoparticle-peptide technology and plans future research to ultimately lead to new therapies. The combo now called SEVA-108, is expected to undergo a comprehensive safety evaluation by the end of this year and clinical trials in patients could start as early as the fourth quarter of 2017.

Dr Larry Burk Speaks on Predictive Cancer Dreams.

Sunday, July 17th, 2016

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Larry Burk, MD, CEHP, President of Healing Imager, PC, in Durham, NC, specializes in teleradiology, EFT, hypnosis and dream work. He was associate professor of radiology and director of integrative medicine education at Duke University Medical Center from 1998-2004.  He was a founding member of the American Board of Scientific Medical Intuition and a board president of the Rhine Research Center. His book Let Magic Happen: Adventures in Healing with a Holistic Radiologist was published in 2012.

Dr. Burk co-facilitates week long retreats at The Monroe Institute in Faber, VA, with medical intuitive Winter Robinson, MA, on Medical Intuition and Symbolic Dis-ease, which also include EFT, imagery and dream work.  He published his paper “Warning Dreams Preceding the Diagnosis of Breast Cancer: A Survey of the Most Important Characteristics” in the May/June 2015 issue of Explore: The Journal of Science and Healing. A link for the paper is on his homepage at www.larryburkmd.com.

Enjoy the Interview Below:

 

 

Can Exercise Improve Memory of Breast Cancer Survivors”

Friday, July 15th, 2016

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A new study published in Psycho-Oncology concluded that moderate to vigorous physical activity is related to improved subjective memory in breast cancer survivors. Researchers believe the exercise alleviates stress and benefits women psychologically, that in turn aids in memory. Researchers looked at memory and exercise in breast cancer survivors in two groups of 1,477 women and 362 women. Findings showed a link between improved memory with higher levels of physical activity in both groups of breast cancer survivors. They also found that increased physical activity had fewer subjective memory problems, a higher level of confidence. lower distress and fatigue that all influenced their subjective memory.

Can Acupressure reduce Fatigue in Breast Cancer Survivors?

Wednesday, July 13th, 2016

 

logo1267406_mdA new study published in JAMA Oncology concluded that acupressure reduces persistent fatigue in women who have been treated for breast cancer.   Researchers studied 424 breast cancer survivors from the Michigan Tumor Registry and randomized them to relaxing acupressure (often used to treat insomnia) , stimulating acupressure (often used to increase energy), or usual care including typical sleep management techniques. Subjects were taught how to find and stimulate the acupressure points so they could perform it at home once daily for 6 weeks. At the end of the study period, both acupressure treatments resulted in significant, sustained improvement in fatigue. However, only the relaxing acupressure showed an improved sleep quality, and overall improved quality of life.

Overall researchers found that acupressure reduced fatigue by 27 percent to 34 percent over 6 weeks. About 2/3 of the women who did relaxing acupressure obtained normal fatigue levels.

because fatigue is a common long-term effects of breast cancer treatment  that lasts up to 10 years for about 1/3 of women (moderate to severe), and because it was relatively easy to teach the women to do acupressure (learned in about 15 minutes) researchers concluded “Given the brief training required to learn acupressure, this intervention could be a low-cost option for treating fatigue.” Further research is planned.

Can Smoking Interfere with Breast Cancer Treatment?

Friday, June 24th, 2016

 

Logos 005New research published in the British Journal of Cancer  concluded that common treatment for breast cancer works less well in patients who smoke, compared to non-smokers. The study followed 1,016 breast cancer patients in southern Sweden diagnosed between 2002 and 2012. At the time of surgery they were asked whether they were smokers or non-smokers and about one in five said they were a regular smoker or social smoker. The impact of smoking was evaluated based upon type of breast cancer treatment received after surgery.

Results showed that women over age 50 treated with aromatase inhibitors, were affected by smoking. The aromatase treatment prevents the body from generating estrogen in fatty tissue and thereby reduces the risk of recurrence in women with estrogen-receptive positive breast cancer. This treatment worked significantly better in non-smokers. Researchers said “Smokers who were treated with aromatase inhibitors had a three times higher risk of recurrence of breast cancer compared with the non-smokers who got the same treatment.” They also found that “the smokers also had an increased risk of dying, either from the breast cancer or from other illnesses, during the time we followed them.”

However, the researchers found little or no difference between smokers and non-smokers treated with the drug tamoxifen, radiotherapy, or chemotherapy. Despite telling patients of the importance of stopping smoking only ten perce of the 206 smokers stopped in the first year after surgery. Researchers said the number of smokers who stopper was too small to determine if that made a difference in their future risk. More research is needed.

Can A Healthy Lifestyle Reduce Risk for High Risk Breast Cancer Patients.

Wednesday, June 1st, 2016

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A new study published in May, 2016 in JAMA Oncology  concluded that women with a high risk of developing breast cancer based upon family history and genetic risk can reduce the chances of developing the disease by following a healthy lifestyle. Researchers developed a model predicting the risk of breast cancer by analyzing records of more than 17,000 women with breast cancer and nearly 20,000 women without the disease and another 6,000 women from another study group. Individual-level data on risk such as age, weight, smoking status, and  factors on almost 100 common gene variations, each of which are known to have a modest association with breast cancer but in combination they can lead to substantial elevated risk. The common gene variations in the study were quite different from the well known rare mutations in genes such as BRCA1 and BRCA2 where having a single variant can mean a very high risk of developing cancer.

They found that roughly 30 percent of breast cancer cases could be prevented by modifying known risk factors such as drinking less alcohol, losing weight and not taking hormone replacement therapy. They also found that a large fraction of the total preventable cases would occur among women at higher levels because of genetic risk factors, family history and a few other factors that cannot be modified. They found that white women who are at high risk but who had a low body index mass index, who did not drink or smoke, and who did not use hormone replacement therapy, had about the same risk as an average white woman in the United States and that the average chance that a 30 year old white woman will develop breast cancer before age 80 is about 11 percent. Researchers said “People think that their genetic risk for developing cancer is set in stone,. While you can’t change your genes, this study tells us even people who are at high genetic risk can change their health outlook by making better lifestyle choices such as eating right, exercises, and quitting smoking.”

This study is a first step in understanding how advances in the field of genetics can be used to develop preventive strategies to help women improve their odds of avoiding breast cancer.

 

 

 

 

 

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Protein-A Breast Cancer Tumor Suppressor.

Friday, May 27th, 2016

 

Logos 005A new study published recently in online Oncogene concluded that  HOXA5 protein in normal breast cells acts as a tumor suppressor that halts abnormal cell growth. This builds upon  previous research finding that many breast cancer patients have a lower level of HOXA5 protein, a gene product known to control cell differentiation and death, and lower levels of the protein corresponded to poorer outcomes for patients.

In the study, researchers analyzed gene expression from human breast cell lines lacking HOXA5 and found that the protein seems to help maintain several traits in normal breast cancer, including the ability to adhere to other epithelial cells, and the presence of molecules marking the cells as differentiated and not capable of self-renewal like breast stem cells. When they depleted the HOXA5 proein in other breast cell lines in the lab, the cells became more immature, or stemlike, as well as more mobile. They also found that HOCA3 regulates the production of two other proteins, CD24 and E-cadherin, cells, without CD24, the cells begin to revert toward a stem like state, and without E-cadherin, cells lose some of the glue that binds them to other cells.  Consequently, breast cells without HOXA5 were more likely to grow aggressively in lab experiments forming structures similar to those seen as tumor cells ready to metastasize.

After injecting human tumor cells with and without HOXA5 into the mammary fat pad of mice they found that tumor cells containing protein carried anywhere from 10 to 17 times fewer breast stem cells, and tumor growth from the injected cells were about 3 times smaller than those in mice who received tumor cells with depleted levels of HOXA5. Further research is planned on breast cancer and the role of HOXA5,

Does a Low Fat Diet Effect Cancer Death?

Wednesday, April 20th, 2016

A new study presented at the American Association for Cancer Research annual meeting concluded that women who stay on a low fat diet for about eight years  reduce their risk of death from invasive breast cancer and improve their survival rate when compared with women who had not stayed on a low fat diet. Researchers followed 48,835 postmenopausal women between the ages of 50 and 79 with no previous breast cancer. In this randomized clinical trial the women had also had normal mammograms and normal dietary fat intake.  Of this group, 19,541 women were placed on a low fat diet with nutritionist-led group sessions attempting to reduce fat intake  to 20% of energy and increase consumption of fruit, vegetables, and grain. The other 29,294 women followed their usual dietary pattern.

Following about eight years on the low fat diet, 1,767 women were diagnosed with breast cancer. Overall survival from diagnoses of breast cancer was higher in the study group: 82% vs 78%. They believed the reduction was partly due to better survival following the breast cancer diagnosis. Researchers said “This was the first time we had examined the death after breast cancer among this group, and we found that a sustained low fat diet increased the survival rates among postmenopausal women after a breast cancer diagnosis.” They continued “The study also suggests that women would need to remain on the low fat diets to maintain the benefits of the dietary intervention.”

Researchers also found that most breast cancer characteristics such as size, nodal status, and distribution of poor prognosis, triple negative cancers and HER2 positive cancers were similar in the two groups of women. However,m there were fewer progesterone receptor negative cancers in the study group (28.4% vs 33%) and they also  found a lower cardiovascular disease mortality in the study group.