Posts Tagged ‘diagnosis’

Can Prostate Cancer be Confirmed Without a Biopsy”

Wednesday, August 13th, 2014


The Prostate Health Index (phi), a simple, non-invasive blood test that is three times more specific than the PSA to detect prostate cancer is now available according to a report in Science Digest. This may reduce the need for men who test positive for prostate cancer using  a PSA test  to need  a biopsy. Researchers said “The PSA test is based on the fact that men with higher levels of PSA protein are more likely to have prostate cancer.” “However. the problem is that higher levels of PSA can also be caused by a benign enlargement or inflammation of the prostate, leading to many false positives for cancer and ultimately unnecessary invasive biopsies and an increased potential for patient harm.”  Because the blood test is three times more specific in detecting prostate cancer than the PSA it may reduce the need for a biopsy and potential patient harm. Studies showed a reduction of 31% in unnecessary biopsies due to false positives on PSA’s using the phi test.

The phi test uses three different PSA markers as part of a sophisticated algorithm to increase the reliability of determining a patient with a positive PSA has prostate cancer. “The Prostate Health Index is a significant addition to our comprehensive menu of advanced clinical evidence based blood tests that aid in early cancer detection.” said the co-founder of the laboratory offering the test.

Dr Ben Johnson (skin care) and Dr Carl O Helvie (lung cancer) on Holistic Health Show.

Sunday, July 6th, 2014


Dr Ben Johnson has 17 pending patents and is founder and formulator of Osmosis Pur Medical SkinCare. More information was presented earlier on this site and can be found at:



Dr Carl O Helvie has 60 years experience as a nurse practitioner, educator, author and researcher and has published 8 books and chapters in 4 additional ones. He currently hosts the Holistic Health Show. More information is available at:  and


Enjoy the Interview Below:


New Breast Screening Techniques Increases Diagnostic Accuracy

Friday, November 30th, 2012

Research in Radiology reported that the addition of three-dimensional breast imaging (tomosynthesis) to standard digital mammography significantly increases the diagnostic accuracy by the radiologist and reduces false positive recall rates. The researchers said “this is the first major advances in breast imaging and breast cancer screening since the development of breast MRI.” “The beauty of tomosynthesis is that it addresses two major concerns with screening mammograms: missed cancers and false positives. ” Previously , as many as 30 percent of breast cancers were not detected and an additional 8 to 10 percent had to be recalled for further testing.

In the study 1,192 women from five sites, of whom 997 (780 screening cases and 217 women needing biopsy breast imaging) had complete data sets. Each woman had a standard digital mammogram followed by breast tomosynthesis involving a total of less than 3 milligram of radiation dose which is the FDA limit for a single mammogram. Two reader studies were carried out on 312 and 310 cases respectively.  Twelve radiologists participated in the first reader study, and 15 in the second.  A total of 48 cancers were included in the first reader study and 51 cancers in the second.

Compared to digital mammography alone, using both standard mammography and tomosynthesis resulted in increased diagnostic accuracy for all 27 radiologists. In addition, the rate at which cancer present in the breast was correctly identified increased by 10.7 percent for the radiologists in Reader Study 1 and 16 percent for radiologists in Reader Study 2. The researcher said “Almost all of the gains in diagnostic sensitivity with the combined modalities were attributed to the improved detection and characterization of invasive cancers, which are the cancers we are most concerned about because of their potential to metastasize.”

In addition, the combined modalities compared to standard digital mammography  significantly reduced the false positive recall rate for all 27 radiologists by 38.6 percent and 17.1 percent in Reader Study 1 and 2 respectively.

Improved Test For Cervical Cancer Detection.

Wednesday, November 28th, 2012

Research reported at Medicalxpress.,com stated that a  new method of minimizing the number of missed cases of cervical cancer and making the diagnoses more reliable has been found that may decrease the number of deaths annually. Despite a reduction in the number of women diagnosed with and dying from cervical cancer there are still 250 deaths and 500 new cases annually in Sweden.

The test currently used has a low sensitivity requiring cell samples to be taken at least every three years. Unreliable results also mean many tests must be repeated adding cost to care and anxiety among women involved. The new test is a  complementary test that minimize4s the number of missed cases. The researcher says “Around 70 per cent of all cervical cancer cases are caused by two specific virus types, known as HPV16 and HPV18. We have developed a method that identifies proteins of these oncogenic viruses in cells, enabling a more objective interpretation of the test results.”  Researchers believe this will produce a more reliable diagnosis in uncertain cases and reduce missed cases and recalling women with samples that are difficult to interpret.

Diagnosing Lung Cancer with a Virtual Guided Bronchoscopy System.

Friday, October 12th, 2012

Several news sited reported on researchers who say they have patented a virtual bronchoscopy system that improves lung cancer diagnosis by enabling endoscopic examination of peripheral lung lesions.  The goal is to help physicians decide whether  bronchscopy is necessary and avoid potential risks and discomfort for the patient if it is not.

Using this system based upon 2D computer tomography scans, pulmonologists can virtually explore a patient’s airways and simulate the flexible bronchscope movements to be made during the real exam. Then the pulmonologist can plan an access route from the trachea to the peripheral lung lesion  and also  determine if the tip of the bronschoscope will reach the injury.  If not, they can calculate the distance remaining and the biopsy technique to use. This allows them to  know whether or not to continue with the procedure and, if not, avoid a futile exam. The system was developed as part of a three year project that aims to study, implement and assess the guided bronchscopy systems for peripheral lung lesion examinations.

Simple Two Minute Questionaire May Lead to Better Early Detection for Ovarian Cancer

Wednesday, September 26th, 2012

A report in the Open Journal of Obstetrics and Gynecology concluded that a simple three question paper and pencil survey,  given in the doctor’s office and taking less than 2 minutes can effectively identify those women who experience symptoms that may indicate ovarian cancer. Questions were asked about the frequency  and duration of the following three symptoms: abdominal or pelvic pain, feeling full quickly and/or unable to eat normally, and abdominal bloating and/or increased abdominal size.

1200 women, age 40 to 87 were included in the sample and more than half reported being post-menopausal and about 90% were white. About half of the sample had been seen for routine care such as mammography and the other half were seen for current health concerns or follow up of earlier health problems. Five percent of the sample had positive scores on the test indicating a need for follow up. Of this group of 60 women one was with ovarian cancer shortly thereafter. Of the 95% of women who tested negative on the test, none developed ovarian cancer over the next twelve months. The authors said “Women with symptoms that are frequent, continual and new to them in the past year should talk to their doctor, as they may be candidates for further evaluation with ultrasound and blood tests that measure markers of ovarian cancer such as CA-125. ” Recent research indicates that approximately one in 140 women with symptoms may have ovarian canccder. Aggressive follow-up of these symptoms can lead to diagnosis when ovarian cancer can be caught earlier and more effectively treated.”

New Screening Test for Lung Cancer

Friday, September 23rd, 2011


In a new study published in Nature Nanotechnology the researchers discussed a possible new screening test for lung cancer that would identify cases at an earlier stage than is now possible. They used blood plasma samples to detect a change in a specific small RNA (ribonucleic acid) molecule that is often elevated in patients with lung cancer. Putting an extract of the blood plasma through a tiny hole in a thin membrane that is just big enough for a single molecule to pass, and applying an ionic current they could measure changes in the current that occur when molecules associated with lung cancer are present. The altered current acts as a signal related to lung cancer according to the researcher. “This technology could possibly be used in the future to detect other cancer types as well as other types of diseases with specific DNA and RNA in the blood” stated the researcher.

Researchers Find Way to Improve Diagnosing of Diabetes

Wednesday, September 7th, 2011


Research published in the British J of General Practice concluded that a simple finger prick during routine eye exams or dental appointments could help identify millions with previously undiagnosed type 2 diabetes. Although it is estimated that there are 150 million people worldwide with diabetes the researchers say up to 50% of these are believed to be undetected. And early detection could lead to better management and prevention of complications.

In their pilot study, researchers, found that out of 1,002 people visiting opticians for eye examinations who had one or more diabetic risk factors (increased body mass, age over 40) almost 32 percent had elevated blood glucose levels and were referred to their general practitioner for follow up. In the study subjects were asked a number of questions to identify diabetes risk factors and if they had one or more, optical assistants carried out a simple finger prick to assess blood glucose levels. Of the 1,002 tested, 318 had blood glucose levels of 6.1 or higher and were advised to see their general practitioner, and 5 had blood glucose levels higher than 12.1 and were told to immediately see their general practitioner. Of these, 162 followed through and 138 of these were investigated further. Of these 9 were diagnosed with pre-diabetes and 7 with diabetes.

Natural Solutions to Diabetes Interviews Now Online

Sunday, September 4th, 2011

Yesterday, Dr Carl O Helvie, Host, Holistic Health Show interviewed Dr Michael Murray and Dr Michael T. Smith for the opening of the Series on Diabetes.

Dr Michael Murray is author of over 30 books including How to Prevent and Treat Diabetes with Natural Medicine. and has appeared on hundreds of radio and T.V., shows. He is chairman of Dr Murray Natural living and is one of the world’s leading authorities on natural medicine. more information was presented earlier on this site or can be found at:

Dr Michael T. Smith is a naturopathic physician who specializes in classical homeopathy and nutrition and is part of the North Carolina Association of Naturopathic Physicians. He practices at the Carolina’s Natural Health Center in Matthews, North Carolina. More information was presented earlier on this site or can be found at:

Enjoy the Interviews Below:

Early Detection of Prostate Cancer Using A Urine-Sniffing Dog

Friday, February 18th, 2011


A new study published in this months issue of European Urology concluded that a dog can be trained to successfully detect prostate cancer by smelling urine. In the study a Belgian shepherd was trained by operant-conditioning to sniff urine and recognize samples from those who have prostate cancer. After a 24 month training period the dog’s ability to differentiate prostate and control urine was tested. All urine was frozen and later heated to the same temperature.

Sixty six patients who had elevated prostate-specific antigens or abnormal digital rectal exams submitted urine and all underwent prostate biopsies. There were two groups consisting of 33 subjects with prostate
cancer and 33 controls who had negative biopsies. The dog was able to correctly designate the cancer samples of urine in 30 of 33 cases. Of the three misdiagnosed cases, one patient was re-biopsied and found to have prostate cancer. The sensitivity and specificity of the test was 91%. The researchers believe this could be a potentially useful screening tool for prostate cancer.

More information is available at: