Posts Tagged ‘inflammation’

Dr Sunil Pai discusses Inflammation Nation.

Sunday, November 20th, 2016


Sunil Pai, MD is Board Certified in Holistic Integrative Medicine. After his residency in Family Medicine at the University of New Mexico he became Board Certified in Family Medicine.  He was one of the first physicians 16 years ago in the U.S. to become a Fellow of the Program in Integrative Medicine at University of Arizona (Class 2002) directed by Dr. Andrew Weil. He is certified by Dr. Deepak Chopra as a Primordial Sound Meditation Instructor and a Creating Health (Ayurveda Lifestyle) Instructor. He is also certified in Functional Medicine, Physiological Regulating Medicine, Medical Acupuncture and Neuro-Acupuncture through Stanford University School of Medicine and Dr. Jason Hao. Dr. Pai is the Vice President of the Neuro-Acupuncture Institute, a non-profit organization focusing on teaching physicians neuroacupuncture which is focused for pain conditions and neurological dysfunction such as stroke, multiple sclerosis, parkinsons and traumatic brain injury.  Dr. Pai also specializes in Auriculotherapy focusing on treatment of both food and inhalant allergies. Dr. Pai is also certified in Plant-Based Nutrition from Cornell University and the T. Colin Campbell Foundation and teaches each patient about the health benefits of eating whole food plant based diets. Dr. Pai has undergone specialized training in Ayurvedic Medicine at the Sri Dharmasthala Manjunatheshwara College of Ayurveda, and Intensive Yoga Therapies at the Vivekananda Yoga Anusandhana Samsthana in India.

Sunil Pai, MD is a Deacon of the House of Sanjevani Integrative Medicine Health & Lifestyle Center located in Albuquerque, an Integrated Auxiliary of the Priory of Santa Fe.  As a nonprofit organization, they provide full service health education and Integrative Medicine services with emphasis in indigenous and natural medicines. Sanjevani is certified by the Physicians Committee for Responsible Medicine (PCRM), as an Educational Alliance Partner for delivering evidence based, clinical plant based nutritional programs.

Dr. Pai specializes in custom formulation of dietary supplements including vitamins, minerals, Ayurvedic herbs, medical foods, and homeopathics using safe, clinically effective ingredients. He has been a consultant to various nutraceutical companies as well as functional medicine testing companies. Over the past 14 years, Dr. Pai has studied the processing of raw materials from farm to manufacturing and from the bench top research to clinical studies. His interest in the benefits of natural therapies led to the development of Sanjevani nutraceutical products. Dr. Pai has become internationally recognized by his Sanjevani’s flagship product, Bosmeric-SR®, the strongest natural supplement for pain and inflammation support available worldwide. The all-natural, patented ingredients in a bi-layered tablet provides an immediate action within 20 minutes and sustained release over an 8 hour period.

Dr. Pai recently released his critically acclaimed book An Inflammation Nation (Forward by Dr. Andrew Weil), The Definitive 10-step Guide to Preventing, Treating and Reversing All Diseases Through Diet, Lifestyle and the Use of Natural Anti-Inflammatories for the prevention and treatment of chronic. More information is available at:

Lise Alschuler, Naturopathic Physician, Discusses Prevention and Treatment of Cancer

Sunday, December 20th, 2015

LiseHeadshotStripedShirtLise Alschuler is a naturopathic doctor with board certification in naturopathic oncology and has been practicing since 1994. She graduated from Brown University with an undergraduate degree in Medical Anthropology and received a doctoral degree in naturopathic medicine from Bastyr University. Dr. Alschuler is past-President of the American Association of Naturopathic Physicians and a founding board member and current President of the Oncology Association of Naturopathic Physicians. She also currently serves as President Emeritus on the board of the Naturopathic Post-Graduate Association. Dr. Alschuler works as an independent consultant in the area of practitioner and consumer health education. She is the Executive Director of TAP integration, a nonprofit educational resource for integrative practitioners. She maintains a naturopathic oncology practice out of Naturopathic Specialists , based in Scottsdale AZ. Previously, she was the department head of naturopathic medicine at Midwestern Regional Medical Center – Cancer Treatment Centers of America. She was also the clinic medical director and botanical medicine chair at Bastyr, as well she was on the faculty of Southwest College of Naturopathic Medicine. The American Association of Naturopathic Physicians recognized Dr. Alschuler in 2014 as Physician of the Year. She also received an honorary degree from the Canadian College of Naturopathic Medicine and the Joseph Pizzorno Founders award from Bastyr University in the same year.

Dr. Alschuler is the co-author of The Definitive Guide to Cancer and The Definitive Guide to Thriving After Cancer. She co-created, and co-hosts a radio show, Five To Thrive Live! on the Cancer Support Network about living more healthfully in the face of cancer. She calls Tucson AZ and Chicago, IL home. Learn more at

Prostate Cancer, Inflammation, and Vitamin D.

Wednesday, October 29th, 2014


A new study published in the journal Prostate concluded that inflammation may be the link between Vitamin D and prostate cancer. Specifically the study demonstrated that the gene GDF-15, known to be upregulated by Vitamin D, is missing in samples of human prostate cancer driven by inflammation.  The researchers wanted to determine what genes Vitamin D is turning off in prostate cancer because it was known that puting vitamin D on prostate cancer cells inhibits their growth but has not been declared an anticancer agent.

The researchers said ” We thought there might be high levels of GDF-15 in normal tissue and low in prostate cancer, but we found that in a large cohort of human prostate tissue samples, expression of GDF-15 did not track with either normal or cancerous prostate tissue.” They then discovered that GDF-15 was uniformly low in samples of prostate tissue containing inflammation.  They said “Inflammation is thought to drive many cancers including prostate, gastric and colon. Therefore, GDF-15 may be a good thing in keeping prostate tissue healthy–it suppresses inflammation, which is a bad actor potentially driving prostate cancer.” They also found that the gene GDF-15 supresses inflammation by inhibiting another target, NFkB that has been shown to promiote inflammation and contribute to tumor formation in previous studies. Research is ongoing.

Dr Craig Weiner (ADHD) and Julie Daniluk (Nutrition and Inflammation) Interviews Available.

Sunday, February 16th, 2014

dr craig weinerjulie daniluk My guests on Saturday were Dr Craig Weiner and Julie Daniluk.

Dr Weiner is a licensed psychologist in private practice and has written 3 books on ADHD. More information was presented earlier on this site and can be found at:

Dr Julie Daniluk is a nutritionist, host of Healthy Gourmet on OWN (Oprah Winfrey Network) , author of Meals that Heal Inflammation, has spoken in Parliament, and been interviewed on numerous radio and television shows. More information was presented earlier on this site and can be found at:

Enjoy the Interviews below:


Can Green Tea Inhibit Prostate Cancer Tumor Growth?

Wednesday, October 31st, 2012

A new study presented at the 11th annual AACR International conferences on Frontiers in Cancer prevention Research concluded that men with prostate cancer who consumed green tea prior to undergoing surgery (prostatetectomy) had reductions in markers of inflammation. The researcher said ” This research offers new insights into the mechanisms by which green tea consumption may reduce the risk of prostate cancer by opposing processes such as inflammation, which are associated with prostate cancer growth.”

Sixty seven men with prostate cancer scheduled for prostatect0my were randomly assigned to a group either receiving 6 cups of green tea or water daily for 3 to 8 weeks depending upon their scheduled surgery. Researchers collected blood and urine samples before and after the green tea or water consumption and collected prostate tissue following the pathology exam.

Data showed the prostate specific antigen (PSA) concentrations were significantly lower at the end of the study compared with baseline levels in men consuming green tea . In addition, prostate tissue PSA protein expression was lower in en assigned to green tea consumption+ compared to men drinking water (control group,) at the end of the study. In addition, the immunostaining analysis showed that the nuclear factor kappa B, a marker of inflammation, was significantly lower in the men assigned to consume green tea compared to those in the water drinking group. Further research is planned.

Interviews with Dr Mark Moyad, Dr Thomas O’Bryan, Dr Carl O Helvie now Available for Listening.

Sunday, October 28th, 2012

Interviews with Dr Mark Moyad,  Dr Thomas O’Bryan,and  Dr Carl O Helvie  follow. Dr Moyad occupies an endowed position -at the University of Michigan, is internationally known for his work in cancer and immunology, has published 9 books and over 10 articles and traveled around the world lecturing to health care professionals and others. More of his extensive biography was presented earlier on this site.

Dr Thomas O’Bryan is an international recognized speaker and workshop leader specializing in gluten sensitivity and celiac disease.  More of his biography was presented earlier on this site.

Dr Carl O Helvie, a registered nurse with a doctorate in public health and 60 years experience, is author of 8 books, over 100 articles and international presentations, and host of the Holistic Health Show.

The interviews follow:

Interviews with Dr Jacob Teitelbaum (Fibromalgia, CFS, Alzheimers) and Kristin Mallon (Midwifery) Now Available for Listening.

Sunday, September 30th, 2012

Guests on the show yesterday were Dr. Jacob Teitelbaum (left) and Kristin mallon (right).

Dr Teitelbaum is one of the leading authorities on fibromyalgia and chronic fatigue syndrome and has written best selling books, appeared on major radio and television programs and spoken internationally. More information is available at:

Kristin Mallon is a certified nurse midwife with a masters in nursing and is in private practice in northern new Jersey and is a published author and breastfeeding counselor. More information is available at:

Enjoy the interview below:

Research Finds Link Between Inflammation, Bacterial Communities and Cancer.

Friday, August 24th, 2012

A new study published online in the journal Science concluded that a significant disturbance in the human body can profoundly alter the makeup of an otherwise stable microbial community coexisting within it and that changes in the internal ecology can result in unexpected and drastic consequences for human health. In a series of experiments using mice prone to intestinal inflammation the researchers found that inflammation caused simplification in diverse communities of gut microbes and allowed a new bacterial population  to establish a foothold. These pathogens then may damage host cells increasing the risk of developing colorectal cancer. Bacteria taxa often invading the disturbed intestinal ecosystem were E.Coli and related bacteria. By putting E. coli bacteria in mice raised in a sterile environment the researchers found that the presence of  E. coli promoted  tumor formation but when the region of the E. coli genome responsible for DNA damage was removed the ability of the E. coli to cause tumors was significantly decreased.  Researchers also found an E. coli variant with the suspected genes in a high percentage of human patients with colorectal cancer and irritable bowel disease.

There first study looked at determining a clear connection between the physiological condition of intestinal inflammation and a subsequent change in microbial communities in the gut. They used mice that are genetically prone to inflammation because they lack the gene that suppresses the inflammation response. The researchers compared bacterial communities in the inflamed gut of this group of mice with those bacteria  in healthy field mice. They found the diversity of different kinds of bacteria was lower in the mice with genetically facilitated inflammation but there was little difference in the microbial diversity between those that had inflammation and those that had cancer and this indicated that inflammation was the critical factor affecting microbe populations. They said ” A shift in the microbial community is associated with inflammation.” “It is interesting that the microbial community is actually  changing with the disease state, which indicates that it is either responding to or contributing to the disease state.”

Next they studied whether or not there was a relationship between E. coli and colorectal cancer. For this they raised sterile (bacteria free) mice that were genetically prone to inflammation  and inoculated each mouse with either E. coli variant (NC lOl) or Enterococcus faecalis, another common gut bacteria.  Both groups of the inflammation prone mice developed severe gut inflammation (colitis) but of significance, 80 percent of the E. coli infected mice also developed cxolorectal cancer, while the other group remained cancer-free. The researchers said it was the presence of the  E. coli in an inflammed environment that lead to the cancer rather than the inflammation itself.

Next they wanted to know what was it in the E. coli that caused cancer. Knowing that some strains of E.coli have a set of genes known as “the pks island” that have been implicated in pathways causing DNA damage, they innoculated mice with a modified NC lOl  E. coli that lacked the pks island and the mice still developed inflammation but  had a dramatically  reduced rate of tumors. Researchers concluded that host-microbial interactions that allow E. coli to cause inflammation are distinct from the interactions that cause the inflammation to progress to cancer.

Their next step was to look at human subjects to see if there was an association of pks containing bacteria with colorectal cancer. Subjects included 24 healthy people, 35 people with irritable bowel disease (including inflammation) , and 21 with colorectal cancer.  Researchers said “Remarkably, we found the bug with pks in only 5 out of 24 controls (29% in healthy people), but if you look at people with inflammatory bowel disease, the bug and pks were present in 14 out of 35 (40%), and with people with colorectal cancer it was 15 out of 21 (66.7%).”  “These are exciting results because they suggest there may be a direct link between changes in tyhe gut microbiome and the progression from inflammation to cancer.”

Are Exercise and Caffeine Protective Against Sun Exposure Skin Cancer?

Friday, April 13th, 2012

A new study reported at the American Association of Cancer Research last week concluded that the combined effects of exercise and caffeine consumption may prevent skin cancer and also prevent inflammation related to other obesity-linked diseases. These results were found in a mouse model study but the researcher believes  “we may extrapolate these findings to humans and anticipates that we we would benefit from these combination treatments as well.”

Using mice at high risk of developing skin cancer researchers evaluated the effects of caffeine and exercise and found that mice that took a dose of caffeine and exercised on a running wheel had 62% fewer skin tumors. In addition, the volume of tumors also decreased by 85% compared with mice that did not exercise or take caffeine.  Positive effects were also found for either intervention alone but to a lesser degree.  Findings were a 27% reduction in skin tumors for caffeine only mice and a 61% reduction in tumor size. They found the tumor activity was reduced by 35% and the tumor volume by 70% in exercise-only mice. They also found that combined exercise and caffeine reduced weight and inflammation when mice were fed a high-fat diet of omega-6 fatty acid-rich  foods for two weeks.  These results were again higher when the two interventions were combined than with either one alone.

How Does Mate Tea act on Colon Cancer Cells?

Friday, February 3rd, 2012

An invitro study published in Molecular Nutrition & Food Research concluded that “caffeine derivatives in mate tea not only induced death in human colon cancer cells, they also reduced important markers of inflammation.” Inflammation can trigger the progression of cancer. In the study, researchers isolated, purified, and then treated human colon cancer cells with caffeoylquinic acid (CQA) from mate tea and as they increased the CQA concentration cancer cells died as a result of apoptosis. In other words, “cancer cells self-destruct because its DNA has been damaged.” The researchers identified the mechanism that led to cell death and have completed a follow up study in which they compare the development of colon cancer in rats that drank mate tea as their only source of water with a control group that drank only water. These results will be published soon.
The researcher concluded “We believe there’s ample evidence to support drinking mate tea for its bioactive benefits especially if you have reason to be concerned about colon cancer. Mate tea bags are available in health food stores and are increasingly available in large supermarkets.”